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Database: UniProt
Entry: D4AWQ0_ARTBC
LinkDB: D4AWQ0_ARTBC
Original site: D4AWQ0_ARTBC 
ID   D4AWQ0_ARTBC            Unreviewed;      1490 AA.
AC   D4AWQ0;
DT   18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT   18-MAY-2010, sequence version 1.
DT   31-JUL-2019, entry version 52.
DE   SubName: Full=RNA helicase/RNAse III, putative {ECO:0000313|EMBL:EFE32431.1};
GN   ORFNames=ARB_00616 {ECO:0000313|EMBL:EFE32431.1};
OS   Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371)
OS   (Trichophyton mentagrophytes).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC   Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX   NCBI_TaxID=663331 {ECO:0000313|EMBL:EFE32431.1, ECO:0000313|Proteomes:UP000008866};
RN   [1] {ECO:0000313|Proteomes:UP000008866}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-4681 / CBS 112371 {ECO:0000313|Proteomes:UP000008866};
RX   PubMed=21247460; DOI=10.1186/gb-2011-12-1-r7;
RA   Burmester A., Shelest E., Gloeckner G., Heddergott C., Schindler S.,
RA   Staib P., Heidel A., Felder M., Petzold A., Szafranski K.,
RA   Feuermann M., Pedruzzi I., Priebe S., Groth M., Winkler R., Li W.,
RA   Kniemeyer O., Schroeckh V., Hertweck C., Hube B., White T.C.,
RA   Platzer M., Guthke R., Heitman J., Woestemeyer J., Zipfel P.F.,
RA   Monod M., Brakhage A.A.;
RT   "Comparative and functional genomics provide insights into the
RT   pathogenicity of dermatophytic fungi.";
RL   Genome Biol. 12:R7.1-R7.16(2011).
CC   -!- SIMILARITY: Belongs to the helicase family. Dicer subfamily.
CC       {ECO:0000256|PROSITE-ProRule:PRU00657}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:EFE32431.1}.
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DR   EMBL; ABSU01000015; EFE32431.1; -; Genomic_DNA.
DR   RefSeq; XP_003013071.1; XM_003013025.1.
DR   STRING; 63400.XP_003013071.1; -.
DR   EnsemblFungi; EFE32431; EFE32431; ARB_00616.
DR   GeneID; 9523151; -.
DR   KEGG; abe:ARB_00616; -.
DR   eggNOG; KOG0701; Eukaryota.
DR   eggNOG; COG0571; LUCA.
DR   Proteomes; UP000008866; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004525; F:ribonuclease III activity; IEA:InterPro.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   CDD; cd00593; RIBOc; 2.
DR   Gene3D; 1.10.1520.10; -; 2.
DR   Gene3D; 3.30.160.380; -; 1.
DR   InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR   InterPro; IPR038248; Dicer_dimer_sf.
DR   InterPro; IPR005034; Dicer_dimerisation_dom.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000999; RNase_III_dom.
DR   InterPro; IPR036389; RNase_III_sf.
DR   Pfam; PF00270; DEAD; 1.
DR   Pfam; PF03368; Dicer_dimer; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF00636; Ribonuclease_3; 2.
DR   SMART; SM00490; HELICc; 1.
DR   SMART; SM00535; RIBOc; 2.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF69065; SSF69065; 2.
DR   PROSITE; PS51327; DICER_DSRBF; 1.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
DR   PROSITE; PS00517; RNASE_3_1; 2.
DR   PROSITE; PS50142; RNASE_3_2; 2.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000313|EMBL:EFE32431.1};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000008866};
KW   Helicase {ECO:0000313|EMBL:EFE32431.1};
KW   Hydrolase {ECO:0000313|EMBL:EFE32431.1};
KW   Nucleotide-binding {ECO:0000313|EMBL:EFE32431.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008866};
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00657}.
FT   DOMAIN      137    273       Helicase ATP-binding.
FT                                {ECO:0000259|PROSITE:PS51192}.
FT   DOMAIN      442    623       Helicase C-terminal.
FT                                {ECO:0000259|PROSITE:PS51194}.
FT   DOMAIN      657    751       Dicer dsRNA-binding fold.
FT                                {ECO:0000259|PROSITE:PS51327}.
FT   DOMAIN     1020   1165       RNase III. {ECO:0000259|PROSITE:PS50142}.
FT   DOMAIN     1208   1389       RNase III. {ECO:0000259|PROSITE:PS50142}.
FT   REGION        1     53       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COILED      605    625       {ECO:0000256|SAM:Coils}.
SQ   SEQUENCE   1490 AA;  168937 MW;  0077C592BB65DD4B CRC64;
     MAAAKPELPG QMLALEEHKW GRKRSRSSSG SGDMPQNEAA QKAGFDSLED APDTIRPRGY
     QREMLEASIK QNIIVAVSLC ICLLHIWLKR LLIPQPDGHW QWKDSNVSEL YTSLKTLRYD
     QLNDQAPSNT IGHIYSAILR IRYELERCSN DKLVWFLAPR VPLAEQQYRA ISEQLPAYQT
     KILTGADNLE RWSTQQIWDA FLLNTRIVVS TPQILLDVLS NGFITLRRIA LLVFDEDQLS
     ETNDLPSILG LTASPTSKLI EDSLSLLMES RQLEQNLDAF CKTPAIHREE MMQYVHIPEL
     RRISYQKDSI IPHNMEMKFL HMLDDIDIES DPFFQRHKGK TDSKSTEKCL RALARKTPCL
     DQLKRCFTKI SHMYGELGHW ASSAFISEIY RRTREKRAKL VDHSWSEWDR DDSSFMCNAL
     EPVVAIMGER CWNSTPDAVS QKVEHLIDLL SSELTGSSRG IIFVEQRATA VMLSHLISHY
     PELTHIKSDY FLGNSAFSDR KADLTELSKP GDMKNSIADL KSGKKNLLVA TSVLEEGIDV
     SACDLVVCFD PPKQLRSFVQ RRGRARKKSS KFVIFYAEDD TATYKDWEAM EDIMKERYLS
     NKEFIERLRE EDDEEEVEYE SLRIESTGYG VTPGLVLWDC LLTIYYSVRA LLTLENARAH
     LSHFCSTIPC EFTDTQPDFI ISKTGIKDML TAKVLLPTVL DLQFREFEGI QAWKREKMAK
     RDAAFQAYLQ LYKAGLVNDH LMPEHCRTTD EEIAHIEKRS SMTTCSEVFN PWKMVSDRWH
     STDTFYQSSI VISSGTEELP RMILILPIPL PCNFTVKLFW NETSTLSASV SPQELTVSDE
     DIVSAPLATH ILLSSVFPSR MNGTSRDFSC IFVPELAKGH GGLESWCTKV SKSILGRDIE
     SGSLRSMGDF GLARRTDIYA RAWVAERFVW MKHVRAEDDS ESVEDEEEEG ETLHVEGEKW
     PKRADFLHPV ANSTDSKPHH TARNCIPARQ SCISMLPVGF AKFALFIPSL IHTIGRYLLA
     EELSKTILSP IGFQNIQLVL TAITATSARE DTNYQRLEFL GDSALKLHAS MQLLAEHPLW
     HEGILSKKKD SIVSNSRLWK AAVDTGLDQF ILTTCFTGAK WRPLYNSTYT DNAGKIGEKS
     TRKLSTKTLA DVVESLIGVA IIDGGENKVL RCLELFLPEI NWLPSGERIE ILYDSAPDFN
     DDCPRDILSK IEPLIDYSFT KKALLAASLS HPSNPISGMT YQRLEFLGDS ILDNIVTRAL
     FRCKKEIPHQ DMHLIRTALV NADFLAFLCM NTSTDETRED VCVSPTGEVE VTSSTRQVSL
     WQYMSHSSTD IVETQQAMAR TFEELRDQIE NALRSGARYP WTLLSTLNAP KFFSDIIESI
     LGAIFIDSRG SILACQKFLT RIGLMDYLQR VLEDDGIDFM HPKQRLGVVA QSLSVQYVVS
     EVHVKPGVTQ WKCQVLVGDE EISRVDDGVS QNQARAKAAD LALEVLRTKN
//
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