ID D4B309_ARTBC Unreviewed; 1148 AA.
AC D4B309;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Nuclear pore complex protein {ECO:0000256|RuleBase:RU365072};
GN ORFNames=ARB_02843 {ECO:0000313|EMBL:EFE30305.1};
OS Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton
OS mentagrophytes).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=663331 {ECO:0000313|EMBL:EFE30305.1, ECO:0000313|Proteomes:UP000008866};
RN [1] {ECO:0000313|Proteomes:UP000008866}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4681 / CBS 112371 {ECO:0000313|Proteomes:UP000008866};
RX PubMed=21247460; DOI=10.1186/gb-2011-12-1-r7;
RA Burmester A., Shelest E., Gloeckner G., Heddergott C., Schindler S.,
RA Staib P., Heidel A., Felder M., Petzold A., Szafranski K., Feuermann M.,
RA Pedruzzi I., Priebe S., Groth M., Winkler R., Li W., Kniemeyer O.,
RA Schroeckh V., Hertweck C., Hube B., White T.C., Platzer M., Guthke R.,
RA Heitman J., Woestemeyer J., Zipfel P.F., Monod M., Brakhage A.A.;
RT "Comparative and functional genomics provide insights into the
RT pathogenicity of dermatophytic fungi.";
RL Genome Biol. 12:R7.1-R7.16(2011).
CC -!- FUNCTION: Functions as a component of the nuclear pore complex (NPC).
CC {ECO:0000256|RuleBase:RU365072}.
CC -!- SUBUNIT: Part of the nuclear pore complex (NPC).
CC {ECO:0000256|RuleBase:RU365072}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nuclear pore complex
CC {ECO:0000256|RuleBase:RU365072}. Nucleus membrane
CC {ECO:0000256|RuleBase:RU365072}.
CC -!- SIMILARITY: Belongs to the nucleoporin Nup84/Nup107 family.
CC {ECO:0000256|RuleBase:RU365072}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFE30305.1}.
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DR EMBL; ABSU01000031; EFE30305.1; -; Genomic_DNA.
DR RefSeq; XP_003010945.1; XM_003010899.1.
DR AlphaFoldDB; D4B309; -.
DR STRING; 663331.D4B309; -.
DR GeneID; 9525062; -.
DR KEGG; abe:ARB_02843; -.
DR eggNOG; KOG1964; Eukaryota.
DR HOGENOM; CLU_005882_1_0_1; -.
DR OMA; RYQGFCK; -.
DR OrthoDB; 2718743at2759; -.
DR Proteomes; UP000008866; Unassembled WGS sequence.
DR GO; GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005643; C:nuclear pore; IEA:UniProtKB-SubCell.
DR GO; GO:0017056; F:structural constituent of nuclear pore; IEA:UniProtKB-UniRule.
DR GO; GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR Gene3D; 1.10.3450.20; -; 1.
DR Gene3D; 1.20.190.50; -; 1.
DR InterPro; IPR007252; Nup84/Nup107.
DR PANTHER; PTHR13003:SF2; NUCLEAR PORE COMPLEX PROTEIN NUP107; 1.
DR PANTHER; PTHR13003; NUP107-RELATED; 1.
DR Pfam; PF04121; Nup84_Nup100; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|RuleBase:RU365072};
KW mRNA transport {ECO:0000256|ARBA:ARBA00022816};
KW Nuclear pore complex {ECO:0000256|RuleBase:RU365072};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU365072};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000008866};
KW Translocation {ECO:0000256|ARBA:ARBA00023010,
KW ECO:0000256|RuleBase:RU365072};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU365072}.
FT REGION 1..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 891..922
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1108..1148
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..19
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..67
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..111
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 899..915
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1108..1126
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1134..1148
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1148 AA; 128607 MW; 2587F5A612E86F08 CRC64;
MSSVSESSVE ESDSMYSDVS PAPPSHLHDV EIIEIDSSED DGYERDDGRQ AIELDDGDSE
EQDSDIVTDN EFEARPGFGD DASMEDEEDE EDEDVDGDDE DEESRDAEED EESAGDVWKP
NGVHHNGING TAPAPAPVSH PSKLRAGRST QRNLISLTAF ATLMLTHVST ETITLSETPE
PPLLLPTGVK DALHPLQHTA DRVVKQIEAY AQSLDNFRRQ GLQPGDTRAF QEACKLVKKY
QQIAEDTAKE LSQPTGARKS LRSSTLVNLS QSYKPNVSVS KDEEASIRRW QLEADTWGLV
FHLLAVGDPE SHMQAQLNQK TALQTLHRYS TDHDIWETFL RTDHFAVENA VMLKWLENTA
RAGIEVMDST ISKLEMDANR GEGLWAHGWL YTKEAIKGAK RLRSWPQPLE PDDPSVTASL
LSSSHNEPLI TQLDPDAVTR QGLGLQKQDQ SFEEATWLEC WKMIRTGKDW LSIREWAKER
LESWRAISLC GSAGDSSLSA KDPSHSSLLR MMNYRSQESW RAACSVLANN PNSNRYERAV
YALISGETGP AYEVCQSWSD FVYVNCNHIL LSRYRDFCKQ LQRKLSYAPK AEVELRVDPP
QYDSIRNFLD TLVKDPRTAK ESKNPYCTIQ AAILGQSYDQ FFNLQANALT KVAQESGEPT
LIPDISSMRT FDQPTLIAAK DNDSLRLTAH LYLILRAVGL VRSDSHYSAT ASINVVRYID
FLREYGATRD IPLYASLLPR DMGNEVLGKV LIEVTDPSER ESHIQMMKRL KIDTSAMIQS
QWRWVLKEAD KKFNPKPIKL VRTVTTGGDR PGKIGHIMKG FISKSKVSPE DENLIRCIDW
HRYISGQWSR ICILGTHLYK RFITAGKIST AREMYKRAKL HQTLVDMTNR GQGPLLEPLT
ENGVSSPTSD GTSEQQKAKT TEKLTREQLL MQAETMLELE QLIQSFDAIE KWGDLMDDYT
NCSDTTQKPA IKKKLHPALD AITHAIEPLC TEWLIQPIDD AEAKELAFIR STYLPEIILA
YHTALYYAGH ILGREILAQC MTLATVVSSS AIITESFMAS GRMGELVDAL TLSSFAMMGT
GQSKLKRKLP HGGTNDIWRI RPIKLDENEE DGQDDAHDDK KVKLNGGENG IDGNHVSGVS
TPTAVSVV
//
