ID D4B352_ARTBC Unreviewed; 1012 AA.
AC D4B352;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 03-MAY-2023, entry version 57.
DE RecName: Full=mRNA 3'-end-processing protein RNA14 {ECO:0000256|RuleBase:RU369035};
GN ORFNames=ARB_02886 {ECO:0000313|EMBL:EFE30207.1};
OS Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton
OS mentagrophytes).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Trichophyton.
OX NCBI_TaxID=663331 {ECO:0000313|EMBL:EFE30207.1, ECO:0000313|Proteomes:UP000008866};
RN [1] {ECO:0000313|Proteomes:UP000008866}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC MYA-4681 / CBS 112371 {ECO:0000313|Proteomes:UP000008866};
RX PubMed=21247460; DOI=10.1186/gb-2011-12-1-r7;
RA Burmester A., Shelest E., Gloeckner G., Heddergott C., Schindler S.,
RA Staib P., Heidel A., Felder M., Petzold A., Szafranski K., Feuermann M.,
RA Pedruzzi I., Priebe S., Groth M., Winkler R., Li W., Kniemeyer O.,
RA Schroeckh V., Hertweck C., Hube B., White T.C., Platzer M., Guthke R.,
RA Heitman J., Woestemeyer J., Zipfel P.F., Monod M., Brakhage A.A.;
RT "Comparative and functional genomics provide insights into the
RT pathogenicity of dermatophytic fungi.";
RL Genome Biol. 12:R7.1-R7.16(2011).
CC -!- FUNCTION: Component of the cleavage factor IA (CFIA) complex, which is
CC involved in the endonucleolytic cleavage during polyadenylation-
CC dependent pre-mRNA 3'-end formation. {ECO:0000256|ARBA:ARBA00002863,
CC ECO:0000256|RuleBase:RU369035}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU369035}.
CC Cytoplasm {ECO:0000256|RuleBase:RU369035}. Note=Nucleus and/or
CC cytoplasm. {ECO:0000256|RuleBase:RU369035}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFE30207.1}.
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DR EMBL; ABSU01000032; EFE30207.1; -; Genomic_DNA.
DR RefSeq; XP_003010847.1; XM_003010801.1.
DR AlphaFoldDB; D4B352; -.
DR STRING; 663331.D4B352; -.
DR GeneID; 9524962; -.
DR KEGG; abe:ARB_02886; -.
DR eggNOG; KOG1914; Eukaryota.
DR HOGENOM; CLU_007630_1_1_1; -.
DR OMA; VQLWSVY; -.
DR OrthoDB; 23291at2759; -.
DR Proteomes; UP000008866; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006378; P:mRNA polyadenylation; IEA:UniProtKB-UniRule.
DR Gene3D; 1.25.40.1040; -; 2.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR045243; Rna14-like.
DR InterPro; IPR008847; Suf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR19980:SF0; CLEAVAGE STIMULATION FACTOR SUBUNIT 3; 1.
DR PANTHER; PTHR19980; RNA CLEAVAGE STIMULATION FACTOR; 1.
DR Pfam; PF05843; Suf; 1.
DR SMART; SM00386; HAT; 5.
DR SUPFAM; SSF48452; TPR-like; 2.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|RuleBase:RU369035};
KW mRNA processing {ECO:0000256|RuleBase:RU369035};
KW Nucleus {ECO:0000256|RuleBase:RU369035};
KW Reference proteome {ECO:0000313|Proteomes:UP000008866}.
FT DOMAIN 678..987
FT /note="Suppressor of forked"
FT /evidence="ECO:0000259|Pfam:PF05843"
FT REGION 1..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 194..234
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 622..658
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 843..951
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..22
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..70
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 78..104
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..227
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 633..647
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 843..888
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 889..919
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 920..937
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1012 AA; 113030 MW; 453B67FA3BAE5E4D CRC64;
MAEEGAEQGY LQSQNLNTDA DAAAGSDSDD YDPSETIQEQ FPANIAASNY NTIPHMSPFA
SSSTSTPAPG ANLPERMPGE SYNNNDSTFS LPTSGAEPKG STTISQIGVF EEGSTGDEDG
GDAEYEPPAA ALSAQVQNSI STSADMSQRS LSENINEPVS HFHVQQQNIA SDQNTPPVSI
NLPASDSHVA YNVQNDSAPK PMQGKSKTPG RSAIQSANSS LPSTPPVAAA ASRTRLPHDR
VGILEDRIKA DPRGDTDAWL ELISEHRSRN KLDSARQVYE RFFKVFPSAA EQWVEYATME
SENNELYKLE QIFTKCLLSI PNVQLWSLYL DYVRRRNNLT TDTSGDARRT ITSAYDLALQ
HIGIDKDSGN IWVDYIQFLR SGPGNIGGSG WQDQQKMDLL RKAYQRAICI PTQSVNTLWK
EYDQFEMGLN KLTGRKFIQD KSPSYMTARS SYTELQNITK ELVRSSLPHL PPAPGYEGDF
SFSKQVEIWK RWIQWEKDDP LVLKEEDLAS YKQRVLYVYK QALMALRFVP EVFFDTADFC
FQNNMETEGN DFLKQGIEAN PESCLLAFKR ADRLELSSVS EQDPKKRGTL VREPYDKLLD
ALYELIAQVR AQEATDIAKL EEQAAQAEPE QPTQLENDDD DDDETGNPPT QESAKAKEIE
SVKKDYAAKV GVLSKAISFV WIALMRAMRR IQGKGKPGEI AGSRQIFADA RKRGRITSDV
YIASALLEYH CYKDPAATKI FERGAKLFPE DEVFALEYLK HLIDINDITN ARAVFETTVR
RLASNPKNVA KAKPIFAFLH EYESRYGDLV QINNLEARMR ELFPEDPSLK QFSHRFSAPS
FDPTTFQPIL SPSQLKPRTI SSLEEPSSRP SSPSIRHPTS NTHSPKRSFP LDEYSDELNR
PRKFIRAESP LKGAAGRREQ QKRLQSNGSS GGPTAARKQP QQPPPSAGPL PRDVVYLLSI
IPPASTYDAT RFSPEMMVNL LRQIELPSSV SQLRLPQQTG AASHQYPQYG ML
//
