ID D4DWD8_SEROD Unreviewed; 606 AA.
AC D4DWD8;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Alpha amylase, catalytic domain protein {ECO:0000313|EMBL:EFE98193.1};
DE EC=3.2.1.20 {ECO:0000313|EMBL:EFE98193.1};
GN Name=malZ {ECO:0000313|EMBL:EFE98193.1};
GN ORFNames=HMPREF0758_0238 {ECO:0000313|EMBL:EFE98193.1};
OS Serratia odorifera DSM 4582.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Serratia.
OX NCBI_TaxID=667129 {ECO:0000313|EMBL:EFE98193.1, ECO:0000313|Proteomes:UP000005723};
RN [1] {ECO:0000313|EMBL:EFE98193.1, ECO:0000313|Proteomes:UP000005723}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 4582 {ECO:0000313|EMBL:EFE98193.1,
RC ECO:0000313|Proteomes:UP000005723};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 13 family.
CC {ECO:0000256|ARBA:ARBA00008061}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFE98193.1}.
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DR EMBL; ADBY01000012; EFE98193.1; -; Genomic_DNA.
DR RefSeq; WP_004954705.1; NZ_GG753567.1.
DR AlphaFoldDB; D4DWD8; -.
DR STRING; 667129.HMPREF0758_0238; -.
DR HOGENOM; CLU_006462_6_4_6; -.
DR OrthoDB; 9805159at2; -.
DR Proteomes; UP000005723; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0032450; F:maltose alpha-glucosidase activity; IEA:UniProtKB-EC.
DR CDD; cd11338; AmyAc_CMD; 1.
DR CDD; cd02857; E_set_CDase_PDE_N; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR006047; Glyco_hydro_13_cat_dom.
DR InterPro; IPR004185; Glyco_hydro_13_lg-like_dom.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR014756; Ig_E-set.
DR InterPro; IPR017069; MalZ.
DR PANTHER; PTHR10357; ALPHA-AMYLASE FAMILY MEMBER; 1.
DR PANTHER; PTHR10357:SF210; MALTODEXTRIN GLUCOSIDASE; 1.
DR Pfam; PF00128; Alpha-amylase; 1.
DR Pfam; PF02903; Alpha-amylase_N; 1.
DR PIRSF; PIRSF036918; Maltodextrin_glucosidase; 1.
DR SMART; SM00642; Aamy; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF51011; Glycosyl hydrolase domain; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000313|EMBL:EFE98193.1};
KW Hydrolase {ECO:0000313|EMBL:EFE98193.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000005723}.
FT DOMAIN 124..518
FT /note="Glycosyl hydrolase family 13 catalytic"
FT /evidence="ECO:0000259|SMART:SM00642"
FT ACT_SITE 333
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR036918-50"
FT ACT_SITE 370
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR036918-50"
FT SITE 445
FT /note="Transition state stabilizer"
FT /evidence="ECO:0000256|PIRSR:PIRSR036918-51"
SQ SEQUENCE 606 AA; 68997 MW; AD79B07FF67B548D CRC64;
MLDAWHQPVP PFVVKKGQRL DITLWLQGDD LPKQVFLRAE PDNEEWLLEM KARAVDGRQR
YQASLPLNEG EATRRYCFKL LWQDRQRWFG PLGWSLMPIG QLAQFALEEP DSGAGWVADQ
LFYQIFPDRF ASSGAAYNLQ SGSYYHHAAG TGVIRRDWQH PLEAQHDAST FYGGDLDGIV
QRLPYLKRLG VTALYLNPIF KAPSVHKYDT EDYYQVDPHF GGNAAFRRLR VSTHKVGMKL
LLDGVFNHTG DSHPWFDRHQ QTEQGACHHP DSPYRNWFNF YPDGTALTWK GNASLPKLNY
AEPAVARAIY GDEDSVVRHW LKPPYSIDGW RLDVVHMLGE NGGASGNLQH LAGIHRAARE
VNPHAYIMGE HFGDARRWLH AGVEDAAMNY MGFALPLRGF LAGLDVALQP LKLDAAETAH
WMDSYRAGLP HNRQLIMFNQ LDSHDTPRFL TLLGGNLPRM QMAAVWLMSW IGVPCLYYGD
EIGLDGDNDP FCRKPFPWDE SQWNYALLNL FQRMAALRKK SKALRRGGCQ VLFAHGETLV
FVRTYQHERV LVALQRDASN HEIALPYSPL LPPGDWQRQE GLGDMQSCDD GVVLRLAEQS
VTLWTL
//
