ID D4EA24_SEROD Unreviewed; 1759 AA.
AC D4EA24;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE SubName: Full=Conjugative transfer relaxase protein TraI {ECO:0000313|EMBL:EFE93292.1};
DE EC=3.6.1.- {ECO:0000313|EMBL:EFE93292.1};
GN Name=traI {ECO:0000313|EMBL:EFE93292.1};
GN ORFNames=HMPREF0758_5024 {ECO:0000313|EMBL:EFE93292.1};
OS Serratia odorifera DSM 4582.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Serratia.
OX NCBI_TaxID=667129 {ECO:0000313|EMBL:EFE93292.1, ECO:0000313|Proteomes:UP000005723};
RN [1] {ECO:0000313|EMBL:EFE93292.1, ECO:0000313|Proteomes:UP000005723}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 4582 {ECO:0000313|EMBL:EFE93292.1,
RC ECO:0000313|Proteomes:UP000005723};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFE93292.1}.
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DR EMBL; ADBY01000080; EFE93292.1; -; Genomic_DNA.
DR RefSeq; WP_004966169.1; NZ_GG753568.1.
DR STRING; 667129.HMPREF0758_5024; -.
DR HOGENOM; CLU_001748_2_1_6; -.
DR OrthoDB; 1634048at2; -.
DR Proteomes; UP000005723; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR CDD; cd17933; DEXSc_RecD-like; 1.
DR CDD; cd18809; SF1_C_RecD; 1.
DR Gene3D; 2.30.30.940; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR014129; Conjug_relaxase_TraI.
DR InterPro; IPR009767; DNA_helicase_TraI_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014059; TraI/TrwC_relax.
DR InterPro; IPR040668; TraI_2B.
DR InterPro; IPR040987; TraI_N.
DR InterPro; IPR014862; TrwC.
DR NCBIfam; NF041492; MobF; 1.
DR NCBIfam; TIGR02686; relax_trwC; 1.
DR NCBIfam; TIGR02760; TraI_TIGR; 1.
DR PANTHER; PTHR43788; DNA2/NAM7 HELICASE FAMILY MEMBER; 1.
DR PANTHER; PTHR43788:SF8; HELICASE WITH ZINC FINGER 2; 1.
DR Pfam; PF13604; AAA_30; 1.
DR Pfam; PF18272; ssDNA_TraI_N; 1.
DR Pfam; PF18340; TraI_2B; 1.
DR Pfam; PF07057; TraI_C; 1.
DR Pfam; PF08751; TrwC; 1.
DR SUPFAM; SSF55464; Origin of replication-binding domain, RBD-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000313|EMBL:EFE93292.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000005723}.
FT DOMAIN 10..284
FT /note="TrwC relaxase"
FT /evidence="ECO:0000259|Pfam:PF08751"
FT DOMAIN 580..632
FT /note="TraI N-terminal subdomain"
FT /evidence="ECO:0000259|Pfam:PF18272"
FT DOMAIN 638..717
FT /note="TraI 2B/2B-like"
FT /evidence="ECO:0000259|Pfam:PF18340"
FT DOMAIN 1460..1616
FT /note="DNA helicase TraI type C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07057"
FT REGION 1723..1759
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1736..1759
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1759 AA; 189030 MW; 7EEE913A73578259 CRC64;
MMSIGQVGPA GKAGDYYTHQ DNYYVLGSMD ERWVGEGAEA LGLSGKVDVK DFVAVLEGKL
PDGSDLTRMV GNENKHRPGY DLTFSAPKSV SIMAMLGGDK RLIAAHNHAV EVAVREIEKM
ASTRVMTDGV SETKLTGNLV VALFNHDTSR DLDPQLHTHA VVANVTQHDG KWQTLSSDTV
GKTGFIESVY ANQVAGGQIY RHILQREVEA MGYETEPTGP HGMWEFKSTE AVREPFSKRS
HAIDAAAGPD ASLKSRDMAT LDTRKAKVTP DQAELFVAWM QQMKSTGFDP KSYQAETQSR
TMVTPSPTPL EAGGDTLVDK AVEQAISALS DRQVNFTHNQ VANKAISYLS GEPGMLDAVR
DGIDRAIERE QLIPLDKEKG VFTSDIHLLD ELSVAQLSRT HIDESAVVIG APRPDPRTGS
LPAYSDAVQT LAQHAPTMAV LSGIGGASVN RARVAEVVAL AREQGRDATV LTVDRQSQQY
LQQSVHLDEG RVLTRAALDS EALFAPNSTL VVDQAEKLTL KETVTLLDGA VRNNVQLVLM
DTEKRKGTGN ALSVMKEAGV PRYQFSGRQA VPAEVVSEPD KAQRFGQLAK GVVQALAEDR
PSVAQVNGPA DQRMLTAMIR DELKETGLLG REETHVATLT PVWLDSKNRG AIDTYREGMV
MERWDADSKQ RERFVIDRVG AQTRNLVLRS AAGEKQTLAV RELDKDWSLF RPGIIAVAEG
ERLRVLGQEG RGKDAMKAGT ELTVLRAGAG ELQVKVAGEP DATQKLGVRT LAVGSDAFSS
VKVAQAYVEG LGASVSSTSA VYAAVKKNEL NSATLSGIAR SGGHITLYSA LDARKTQEKV
AQHPAYRLAG EQVKQLAGEE GLDAAIAGQK SSLFTPQQQA IHLAIPTLEG DNVAFAQAKL
LAGSLSFAAK GVSIDAIQTE IDAQVKRGEL LKVDVAPGVG ADLLVSRASF EAEKSIIRLI
ADGKDSMPAL MSEAAKNQLA SSQKSLTHGQ KESVGLILST TDRFVAIQGY AGVGKTTQFK
AVLAGIDQLP ESERPRVVGL APTHRAVGEM QAAGVDAQTL ASFLHDEGMK VASGEKPDYR
NTLFVVDESS MVGNSDMARA YALIAEGNGR AVMSGDEAQL QPIAPGTPFR LAQGRSAIDM
AVMKEIVRQT PELKPAVYKI IDNDVPGALD VVRAVAPANV PRQANAWVPA QSVMELAVDI
ADIHEAIVSD YMGRTEAARR DTLIITHLNA DRHIINAHIH GERKAAGELK GDAVSLPVLE
TANIRDGELR KLGTWARNRG AVVLLDNTYY RMAAIDSQSR TVSLQDSEGN TRQFSPSSAV
REGVTLYNPR TLEVSVGDRM RFSKSDVERG HVANSTWTVE AIKGDIVTLS DGHQTRTVNP
RLQQHDRHVD LAYAITAHGA QGASERYAIT LEGVDGGREQ MVNRASAYVA LSRAKDHVQV
YTDDEAGWLK AIGKAKERTT AHDAVLGMAP GSQKAAADLY GKAVTLADNA LGRAVLRGSN
LTGNTLAHYV SPGKKYPQPH AMLPMYDANG KPAGAWLAPL ADMQGKSVGG LPTQGRVLGS
DNAQFVALQA SQNNETRMAA SMDAGIRLAA QHPDSGVVVR LQGEGVPFNP QAMTGGKIWV
NDDTLKATAL GSLSSDSAIK LPETPEERQQ RELQAQADKL GREPGAPDPQ RLAGLNDEQL
RALLIRGELR AEDVKAHLPD AVVRDVLGQD AALQRDAAIR QVAREPASTR SRLQQDEQNL
VRDVHPEREL SKEKTLGGD
//
