ID D4GHC2_PANAM Unreviewed; 367 AA.
AC D4GHC2;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=YahK {ECO:0000313|EMBL:ADD75437.1};
GN Name=yahK {ECO:0000313|EMBL:ADD75437.1};
GN OrderedLocusNames=PANA_0270 {ECO:0000313|EMBL:ADD75437.1};
OS Pantoea ananatis (strain LMG 20103).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Pantoea.
OX NCBI_TaxID=706191 {ECO:0000313|EMBL:ADD75437.1, ECO:0000313|Proteomes:UP000001702};
RN [1] {ECO:0000313|EMBL:ADD75437.1, ECO:0000313|Proteomes:UP000001702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 20103 {ECO:0000313|EMBL:ADD75437.1,
RC ECO:0000313|Proteomes:UP000001702};
RX PubMed=20348253; DOI=10.1128/JB.00060-10;
RA De Maayer P., Chan W.Y., Venter S.N., Toth I.K., Birch P.R., Joubert F.,
RA Coutinho T.A.;
RT "Genome sequence of Pantoea ananatis LMG20103, the causative agent of
RT Eucalyptus blight and dieback.";
RL J. Bacteriol. 192:2936-2937(2010).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|ARBA:ARBA00008072}.
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DR EMBL; CP001875; ADD75437.1; -; Genomic_DNA.
DR AlphaFoldDB; D4GHC2; -.
DR STRING; 706191.PANA_0270; -.
DR KEGG; pam:PANA_0270; -.
DR eggNOG; COG1064; Bacteria.
DR HOGENOM; CLU_026673_20_2_6; -.
DR Proteomes; UP000001702; Chromosome.
DR GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05283; CAD1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR047109; CAD-like.
DR InterPro; IPR029752; D-isomer_DH_CS1.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR42683; ALDEHYDE REDUCTASE; 1.
DR PANTHER; PTHR42683:SF85; CINNAMYL ALCOHOL DEHYDROGENASE 6-RELATED; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00065; D_2_HYDROXYACID_DH_1; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001702}.
FT DOMAIN 22..356
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 367 AA; 39978 MW; A7EE958EB31CE227 CRC64;
MIKKSRHTLT GDTMNITHAY AAQDAKSKLA PFDFKPRELR AHDVQLEVLF CGVCHSDLHQ
ARNEWKNTIF PVVPGHEIVG RVTAVGPETQ KYKVGDLVGV GCLVDSCRSC PSCQEGLEQY
CENGFVGTYN GEDRLTGAIT YGGYSTSMVV DEDFVLRIPA NLELAGVAPL LCAGITTYSP
LRHWNVGPGK KVGIVGLGGL GHMGVKIAHA MGAHVVLFTT SPSKIEDGKR LGADEVVISK
DADQMAQHAN SFDFILNTVA AQHDLNPFIT LLKRDGNMTL VGAPEHDHPA PQVFNLIFKR
RSIAGSLIGG IAETQEMLDF CGEHGITSDI ELIAMNQIND AYERMLKSDV KYRFVIDINT
LRDESAA
//
