ID D4GK96_PANAM Unreviewed; 536 AA.
AC D4GK96;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=Multicopper oxidase CueO {ECO:0000256|ARBA:ARBA00041027};
DE EC=1.16.3.4 {ECO:0000256|ARBA:ARBA00038978};
DE AltName: Full=Copper efflux oxidase {ECO:0000256|ARBA:ARBA00042896};
DE AltName: Full=Cuprous oxidase {ECO:0000256|ARBA:ARBA00043090};
GN Name=cueO {ECO:0000313|EMBL:ADD75925.1};
GN OrderedLocusNames=PANA_0758 {ECO:0000313|EMBL:ADD75925.1};
OS Pantoea ananatis (strain LMG 20103).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Pantoea.
OX NCBI_TaxID=706191 {ECO:0000313|EMBL:ADD75925.1, ECO:0000313|Proteomes:UP000001702};
RN [1] {ECO:0000313|EMBL:ADD75925.1, ECO:0000313|Proteomes:UP000001702}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 20103 {ECO:0000313|EMBL:ADD75925.1,
RC ECO:0000313|Proteomes:UP000001702};
RX PubMed=20348253; DOI=10.1128/JB.00060-10;
RA De Maayer P., Chan W.Y., Venter S.N., Toth I.K., Birch P.R., Joubert F.,
RA Coutinho T.A.;
RT "Genome sequence of Pantoea ananatis LMG20103, the causative agent of
RT Eucalyptus blight and dieback.";
RL J. Bacteriol. 192:2936-2937(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=4 Cu(+) + 4 H(+) + O2 = 4 Cu(2+) + 2 H2O;
CC Xref=Rhea:RHEA:30083, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:15379, ChEBI:CHEBI:29036, ChEBI:CHEBI:49552; EC=1.16.3.4;
CC Evidence={ECO:0000256|ARBA:ARBA00036588};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:30084;
CC Evidence={ECO:0000256|ARBA:ARBA00036588};
CC -!- SUBUNIT: Monomer. {ECO:0000256|ARBA:ARBA00011245}.
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DR EMBL; CP001875; ADD75925.1; -; Genomic_DNA.
DR AlphaFoldDB; D4GK96; -.
DR STRING; 706191.PANA_0758; -.
DR KEGG; pam:PANA_0758; -.
DR eggNOG; COG2132; Bacteria.
DR HOGENOM; CLU_009100_2_4_6; -.
DR Proteomes; UP000001702; Chromosome.
DR GO; GO:0005507; F:copper ion binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR CDD; cd04232; CuRO_1_CueO_FtsP; 1.
DR CDD; cd13867; CuRO_2_CueO_FtsP; 1.
DR Gene3D; 2.60.40.420; Cupredoxins - blue copper proteins; 3.
DR InterPro; IPR011707; Cu-oxidase-like_N.
DR InterPro; IPR011706; Cu-oxidase_C.
DR InterPro; IPR045087; Cu-oxidase_fam.
DR InterPro; IPR002355; Cu_oxidase_Cu_BS.
DR InterPro; IPR008972; Cupredoxin.
DR InterPro; IPR006311; TAT_signal.
DR InterPro; IPR019546; TAT_signal_bac_arc.
DR NCBIfam; TIGR01409; TAT_signal_seq; 1.
DR PANTHER; PTHR48267:SF1; BILIRUBIN OXIDASE; 1.
DR PANTHER; PTHR48267; CUPREDOXIN SUPERFAMILY PROTEIN; 1.
DR Pfam; PF07731; Cu-oxidase_2; 1.
DR Pfam; PF07732; Cu-oxidase_3; 1.
DR Pfam; PF10518; TAT_signal; 1.
DR SUPFAM; SSF49503; Cupredoxins; 3.
DR PROSITE; PS00080; MULTICOPPER_OXIDASE2; 1.
DR PROSITE; PS51318; TAT; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000001702};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 59..169
FT /note="Plastocyanin-like"
FT /evidence="ECO:0000259|Pfam:PF07732"
FT DOMAIN 407..535
FT /note="Plastocyanin-like"
FT /evidence="ECO:0000259|Pfam:PF07731"
SQ SEQUENCE 536 AA; 58411 MW; CCB3EBB4ED038C8F CRC64;
MLIMQRRHFL KLSAALGAAG ALPLWSRSLM AATRPPLLIP ALLEADANGL YSLTAMEGTT
QWQGKAVPTW GYNGSLLGPA IRLKRGTTAT INIHNRLKEA TTLHWHGLDI PGEVDGGPQG
VIAPGAMRQV TFTPDQPAAT CWYHPHLHGK TGHQVAQGLA GLILLEDQPS GTLRLPSQWG
TDDVPLIFQD KQLSQSGEHI DYQLDVMRAA VGWFGDMMLT NGVQYPQHAV PRGWLRLRLL
NGCNARSLHI AASDKRPLYV IASDGGLLSE PVKVDSLPLL PGERFEIMVD TSDGNAFDIV
TLPVTQMGMT LAPFDRPLPL VNILPLRIMA SATLPDQLAT LPAVPKTEGL TARWLQLSMD
PQLDQQGMQA LMARYGEKAM GKGGQHAMPM GNDASGMKHD SGAETMDHQN MDHGAMSAAA
YDFHNGNKIN GLAFDMTRPA FNVKQGAVEK WTISGEGDSM LHPFHIHGTQ FRILSENGKP
PAAHRQGWKD MVNVDGWRSE VLVRFNHAAA ADHAYMAHCH LLEHEDTGMM LGFTVT
//
