ID D4GPZ2_HALVD Unreviewed; 378 AA.
AC D4GPZ2; L9VIQ1;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Mandelate racemase-like protein / muconate lactonizing enzyme-like protein {ECO:0000313|EMBL:ADE01606.1};
GN OrderedLocusNames=HVO_B0345 {ECO:0000313|EMBL:ADE01606.1};
OS Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 /
OS NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii).
OG Plasmid pHV3 {ECO:0000313|EMBL:ADE01606.1,
OG ECO:0000313|Proteomes:UP000008243}.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Haloferax.
OX NCBI_TaxID=309800 {ECO:0000313|EMBL:ADE01606.1, ECO:0000313|Proteomes:UP000008243};
RN [1] {ECO:0000313|EMBL:ADE01606.1, ECO:0000313|Proteomes:UP000008243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 /
RC VKM B-1768 / DS2 {ECO:0000313|Proteomes:UP000008243};
RX PubMed=20333302; DOI=10.1371/journal.pone.0009605;
RA Hartman A.L., Norais C., Badger J.H., Delmas S., Haldenby S., Madupu R.,
RA Robinson J., Khouri H., Ren Q., Lowe T.M., Maupin-Furlow J.,
RA Pohlschroder M., Daniels C., Pfeiffer F., Allers T., Eisen J.A.;
RT "The complete genome sequence of Haloferax volcanii DS2, a model
RT archaeon.";
RL PLoS ONE 5:E9605-E9605(2010).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001953; ADE01606.1; -; Genomic_DNA.
DR RefSeq; WP_004041196.1; NZ_AOHU01000021.1.
DR AlphaFoldDB; D4GPZ2; -.
DR PaxDb; 309800-C498_01935; -.
DR EnsemblBacteria; ADE01606; ADE01606; HVO_B0345.
DR GeneID; 8919235; -.
DR KEGG; hvo:HVO_B0345; -.
DR PATRIC; fig|309800.29.peg.373; -.
DR eggNOG; arCOG01168; Archaea.
DR HOGENOM; CLU_030273_3_0_2; -.
DR OrthoDB; 42605at2157; -.
DR Proteomes; UP000008243; Plasmid pHV3.
DR GO; GO:0016836; F:hydro-lyase activity; IEA:UniProt.
DR GO; GO:0009063; P:amino acid catabolic process; IEA:InterPro.
DR CDD; cd03316; MR_like; 1.
DR Gene3D; 3.20.20.120; Enolase-like C-terminal domain; 1.
DR Gene3D; 3.30.390.10; Enolase-like, N-terminal domain; 1.
DR InterPro; IPR036849; Enolase-like_C_sf.
DR InterPro; IPR029017; Enolase-like_N.
DR InterPro; IPR029065; Enolase_C-like.
DR InterPro; IPR018110; Mandel_Rmase/mucon_lact_enz_CS.
DR InterPro; IPR013342; Mandelate_racemase_C.
DR InterPro; IPR013341; Mandelate_racemase_N_dom.
DR InterPro; IPR046945; RHMD-like.
DR PANTHER; PTHR13794; ENOLASE SUPERFAMILY, MANDELATE RACEMASE; 1.
DR PANTHER; PTHR13794:SF58; MITOCHONDRIAL ENOLASE SUPERFAMILY MEMBER 1; 1.
DR Pfam; PF13378; MR_MLE_C; 1.
DR Pfam; PF02746; MR_MLE_N; 1.
DR SFLD; SFLDS00001; Enolase; 1.
DR SMART; SM00922; MR_MLE; 1.
DR SUPFAM; SSF51604; Enolase C-terminal domain-like; 1.
DR SUPFAM; SSF54826; Enolase N-terminal domain-like; 1.
DR PROSITE; PS00908; MR_MLE_1; 1.
DR PROSITE; PS00909; MR_MLE_2; 1.
PE 4: Predicted;
KW Plasmid {ECO:0000313|EMBL:ADE01606.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008243}.
FT DOMAIN 145..241
FT /note="Mandelate racemase/muconate lactonizing enzyme C-
FT terminal"
FT /evidence="ECO:0000259|SMART:SM00922"
FT REGION 341..363
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 378 AA; 41240 MW; 49661C1C1C7B7E2B CRC64;
MHVTDIEVIP ISHRLPDGQG LGDARGFGHD RATTLIRVDT DTGEVGWGEA FAPGSVIAPV
VDEFFRDDVV GMDPFDVRRL AEESYTDPYH FGGSVFVQSA LSGIDVALWD LVGKATGKPV
HRLLGGTPRE TLTAYASTMY FTEADRDIAA PIRDAVDEGF SAAKIKIGTG TDSDVERVRT
ARQLLGDDAR LMVDINGNYR PRQAIRTAKA IEEFDITWME EPVPPENLSG YREVKRGVDV
PLAAGEAHYG RFEFKRLVDD RTVDVAQPNL GRCGGLSEAS RIADLASTEN VAVRPHVWNS
AVGLAAAVQF AASVSDYPHT RHVPDPMLVE FDRSENPLRD EILKSPFDPT GGEVDVPQAP
GLGVEIDEDA VERYRADN
//
