ID D4GQA4_HALVD Unreviewed; 342 AA.
AC D4GQA4; L9UUV3;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 80.
DE SubName: Full=Orc1-type DNA replication protein {ECO:0000313|EMBL:ADE02243.1};
GN Name=orc12 {ECO:0000313|EMBL:ADE02243.1};
GN OrderedLocusNames=HVO_A0072 {ECO:0000313|EMBL:ADE02243.1};
OS Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 /
OS NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii).
OG Plasmid pHV4 {ECO:0000313|EMBL:ADE02243.1,
OG ECO:0000313|Proteomes:UP000008243}.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Haloferax.
OX NCBI_TaxID=309800 {ECO:0000313|EMBL:ADE02243.1, ECO:0000313|Proteomes:UP000008243};
RN [1] {ECO:0000313|EMBL:ADE02243.1, ECO:0000313|Proteomes:UP000008243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 /
RC VKM B-1768 / DS2 {ECO:0000313|Proteomes:UP000008243};
RX PubMed=20333302; DOI=10.1371/journal.pone.0009605;
RA Hartman A.L., Norais C., Badger J.H., Delmas S., Haldenby S., Madupu R.,
RA Robinson J., Khouri H., Ren Q., Lowe T.M., Maupin-Furlow J.,
RA Pohlschroder M., Daniels C., Pfeiffer F., Allers T., Eisen J.A.;
RT "The complete genome sequence of Haloferax volcanii DS2, a model
RT archaeon.";
RL PLoS ONE 5:E9605-E9605(2010).
CC -!- SIMILARITY: Belongs to the BlaI transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00011046}.
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DR EMBL; CP001955; ADE02243.1; -; Genomic_DNA.
DR RefSeq; WP_004043363.1; NZ_AOHU01000087.1.
DR AlphaFoldDB; D4GQA4; -.
DR PaxDb; 309800-C498_10891; -.
DR EnsemblBacteria; ADE02243; ADE02243; HVO_A0072.
DR GeneID; 8923646; -.
DR KEGG; hvo:HVO_A0072; -.
DR PATRIC; fig|309800.29.peg.2089; -.
DR eggNOG; arCOG00467; Archaea.
DR HOGENOM; CLU_025112_0_0_2; -.
DR OrthoDB; 270161at2157; -.
DR Proteomes; UP000008243; Plasmid pHV4.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd18139; HLD_clamp_RarA; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR005650; BlaI_family.
DR InterPro; IPR014277; Orc1/Cdc6_arc.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR NCBIfam; TIGR02928; orc1/cdc6 family replication initiation protein; 1.
DR PANTHER; PTHR10763; CELL DIVISION CONTROL PROTEIN 6-RELATED; 1.
DR PANTHER; PTHR10763:SF22; ORC1-TYPE DNA REPLICATION PROTEIN 3; 1.
DR Pfam; PF13401; AAA_22; 1.
DR Pfam; PF03965; Penicillinase_R; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plasmid {ECO:0000313|EMBL:ADE02243.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008243}.
FT DOMAIN 39..184
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 323..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 342 AA; 38912 MW; AE7C42819E01B31B CRC64;
MIRDARVLRA GFVPREVEHR DAEVNHLSSV LEPITNGEPA DTAIVTGPSG AGKTCISKFV
TERLREEVLD VEATYVNCWR NYTRFRTLYQ ILDDLGATID IHRQSTPHDE LVDRLQQHDG
PRTVVILDEV DQLEDPSVIY DLHSLPQFAI ICIANKEEEL FGRVDDRLVS RLRSSEHVRM
DKYHDEQLYD ILSARAKWGL DEDIITDDQL YRVADAAAGD ARLAIGILRT AAGKADRENH
ERITDDILLD AAEDARAQIK QKSLDSLTPH QRVVYDIVRE HGPVGPSEIH ERYTEDVDDP
RTKRTIRTYL SKMEQYNLLE AEGTSRDREY SLVDSAAASP MQ
//
