ID D4GR19_HALVD Unreviewed; 271 AA.
AC D4GR19; L9V2P0;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 24-JAN-2024, entry version 72.
DE SubName: Full=IclR family transcription regulator {ECO:0000313|EMBL:ADE01890.1};
GN OrderedLocusNames=HVO_A0342 {ECO:0000313|EMBL:ADE01890.1};
OS Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 /
OS NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii).
OG Plasmid pHV4 {ECO:0000313|EMBL:ADE01890.1,
OG ECO:0000313|Proteomes:UP000008243}.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Haloferax.
OX NCBI_TaxID=309800 {ECO:0000313|EMBL:ADE01890.1, ECO:0000313|Proteomes:UP000008243};
RN [1] {ECO:0000313|EMBL:ADE01890.1, ECO:0000313|Proteomes:UP000008243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 /
RC VKM B-1768 / DS2 {ECO:0000313|Proteomes:UP000008243};
RX PubMed=20333302; DOI=10.1371/journal.pone.0009605;
RA Hartman A.L., Norais C., Badger J.H., Delmas S., Haldenby S., Madupu R.,
RA Robinson J., Khouri H., Ren Q., Lowe T.M., Maupin-Furlow J.,
RA Pohlschroder M., Daniels C., Pfeiffer F., Allers T., Eisen J.A.;
RT "The complete genome sequence of Haloferax volcanii DS2, a model
RT archaeon.";
RL PLoS ONE 5:E9605-E9605(2010).
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DR EMBL; CP001955; ADE01890.1; -; Genomic_DNA.
DR RefSeq; WP_004043255.1; NZ_AOHU01000058.1.
DR AlphaFoldDB; D4GR19; -.
DR PaxDb; 309800-C498_10341; -.
DR EnsemblBacteria; ADE01890; ADE01890; HVO_A0342.
DR GeneID; 8923252; -.
DR KEGG; hvo:HVO_A0342; -.
DR PATRIC; fig|309800.29.peg.2011; -.
DR eggNOG; arCOG02798; Archaea.
DR HOGENOM; CLU_062618_6_1_2; -.
DR OrthoDB; 14763at2157; -.
DR Proteomes; UP000008243; Plasmid pHV4.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR014757; Tscrpt_reg_IclR_C.
DR InterPro; IPR005471; Tscrpt_reg_IclR_N.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30136; HELIX-TURN-HELIX TRANSCRIPTIONAL REGULATOR, ICLR FAMILY; 1.
DR PANTHER; PTHR30136:SF35; TRANSCRIPTIONAL REGULATORY PROTEIN; 1.
DR Pfam; PF09339; HTH_IclR; 1.
DR Pfam; PF01614; IclR; 1.
DR SMART; SM00346; HTH_ICLR; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS51077; HTH_ICLR; 1.
DR PROSITE; PS51078; ICLR_ED; 1.
PE 4: Predicted;
KW Plasmid {ECO:0000313|EMBL:ADE01890.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000008243};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 13..72
FT /note="HTH iclR-type"
FT /evidence="ECO:0000259|PROSITE:PS51077"
FT DOMAIN 73..260
FT /note="IclR-ED"
FT /evidence="ECO:0000259|PROSITE:PS51078"
SQ SEQUENCE 271 AA; 30647 MW; CE8B9B2184CFB378 CRC64;
MADEHTTGSP RTLKTVSRAF DVVRALEELD GARVTELANH LDLSKSVVYN YLSTLRAEKF
VVKEEDTYRL SLQFLLVGEY VRYQNILYRI GKPEIEELAE KTGEYAHLAT EQHGLGVNLY
KVSGEKAVGS DYQVNKLQRA DYLHFSATGK AILAHLPKER VEWIIDQYGL PGKTEATITT
REELFEELET IRDRGYSLND EEEIKGLQAI GAPVTNRHGR VLGSISVSGP VRRMKQPEYH
EQLIESVVNT ANVIEVNVNM EESDDDFPTF S
//
