ID D4GRT7_HALVD Unreviewed; 548 AA.
AC D4GRT7;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 30-NOV-2016, sequence version 2.
DT 27-MAR-2024, entry version 83.
DE SubName: Full=Sensor box histidine kinase {ECO:0000313|EMBL:ADE02185.2};
DE EC=2.7.13.3 {ECO:0000313|EMBL:ADE02185.2};
GN OrderedLocusNames=HVO_A0629 {ECO:0000313|EMBL:ADE02185.2};
OS Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 /
OS NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii).
OG Plasmid pHV4 {ECO:0000313|EMBL:ADE02185.2,
OG ECO:0000313|Proteomes:UP000008243}.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Haloferax.
OX NCBI_TaxID=309800 {ECO:0000313|EMBL:ADE02185.2, ECO:0000313|Proteomes:UP000008243};
RN [1] {ECO:0000313|EMBL:ADE02185.2, ECO:0000313|Proteomes:UP000008243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 /
RC VKM B-1768 / DS2 {ECO:0000313|Proteomes:UP000008243};
RX PubMed=20333302; DOI=10.1371/journal.pone.0009605;
RA Hartman A.L., Norais C., Badger J.H., Delmas S., Haldenby S., Madupu R.,
RA Robinson J., Khouri H., Ren Q., Lowe T.M., Maupin-Furlow J.,
RA Pohlschroder M., Daniels C., Pfeiffer F., Allers T., Eisen J.A.;
RT "The complete genome sequence of Haloferax volcanii DS2, a model
RT archaeon.";
RL PLoS ONE 5:E9605-E9605(2010).
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DR EMBL; CP001955; ADE02185.2; -; Genomic_DNA.
DR AlphaFoldDB; D4GRT7; -.
DR PaxDb; 309800-C498_00935; -.
DR EnsemblBacteria; ADE02185; ADE02185; HVO_A0629.
DR KEGG; hvo:HVO_A0629; -.
DR eggNOG; arCOG02364; Archaea.
DR eggNOG; arCOG06712; Archaea.
DR Proteomes; UP000008243; Plasmid pHV4.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF13426; PAS_9; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Kinase {ECO:0000313|EMBL:ADE02185.2}; Membrane {ECO:0000256|SAM:Phobius};
KW Plasmid {ECO:0000313|EMBL:ADE02185.2};
KW Reference proteome {ECO:0000313|Proteomes:UP000008243};
KW Transferase {ECO:0000313|EMBL:ADE02185.2};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 47..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 82..151
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 154..206
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 203..273
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 331..537
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 548 AA; 59887 MW; 02BE6C5DA61DF494 CRC64;
MNDSPLDGLD ARAIALAYLG FGTAGILGGE LLLSATLGAP PAPEAELVKG LAFVAVSTAF
VWALVSRKNR RIERQQASVR SSLDQLRTVV AASPVPIIAV TPEGRVTRWN DAATETFGWG
REEVLGGPLP YDAGADSEDS EEIIRRTIAE NGLSDVQVER QPADGDLREF RLSTAVVRDA
DGEVAEIVGV FVDVTEQQRR ERRLREFEQA VEQAGHAIYL TTPDGEITYV NPAFEETTGY
DAAEVIGEPA SILSSGEMPE TYYERLWRAL QSGETWQERI IDRRKSGELY TAIQTIAPIE
SNGDIDGYVA IQSDVTESEV TRQRLGVLNR MFRHNLRNRM NVIEGYAELI RQNEATDTDE
ELAEAAEAIV EAADDLASLS EKAQTVSDAL ESEGTPRRVS ALVEDAVSRA ESTYPEAAVR
TDIETGLYAR VDSRVGAALD ELIANALKHG GETVRIDVRR TEADDSKLVV RVDDDGPGIP
DEEWRVIKRG EETPLEHGTG MGLWLVHWVV KKAGGSMELE PSSLGGTAVT LKLPIGSERP
RTWFSTDE
//
