ID D4GRW0_HALVD Unreviewed; 364 AA.
AC D4GRW0; L9UNJ9;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 68.
DE SubName: Full=M20 family amidohydrolase {ECO:0000313|EMBL:ADE02885.1};
GN OrderedLocusNames=HVO_0419 {ECO:0000313|EMBL:ADE02885.1};
OS Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 /
OS NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Haloferax.
OX NCBI_TaxID=309800 {ECO:0000313|EMBL:ADE02885.1, ECO:0000313|Proteomes:UP000008243};
RN [1] {ECO:0000313|EMBL:ADE02885.1, ECO:0000313|Proteomes:UP000008243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 /
RC VKM B-1768 / DS2 {ECO:0000313|Proteomes:UP000008243};
RX PubMed=20333302; DOI=10.1371/journal.pone.0009605;
RA Hartman A.L., Norais C., Badger J.H., Delmas S., Haldenby S., Madupu R.,
RA Robinson J., Khouri H., Ren Q., Lowe T.M., Maupin-Furlow J.,
RA Pohlschroder M., Daniels C., Pfeiffer F., Allers T., Eisen J.A.;
RT "The complete genome sequence of Haloferax volcanii DS2, a model
RT archaeon.";
RL PLoS ONE 5:E9605-E9605(2010).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
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DR EMBL; CP001956; ADE02885.1; -; Genomic_DNA.
DR RefSeq; WP_004044505.1; NZ_AOHU01000101.1.
DR AlphaFoldDB; D4GRW0; -.
DR STRING; 309800.HVO_0419; -.
DR PaxDb; 309800-C498_16608; -.
DR EnsemblBacteria; ADE02885; ADE02885; HVO_0419.
DR GeneID; 8924963; -.
DR KEGG; hvo:HVO_0419; -.
DR PATRIC; fig|309800.29.peg.3217; -.
DR eggNOG; arCOG01107; Archaea.
DR HOGENOM; CLU_021802_2_0_2; -.
DR OrthoDB; 133929at2157; -.
DR Proteomes; UP000008243; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.360; -; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR001261; ArgE/DapE_CS.
DR InterPro; IPR036264; Bact_exopeptidase_dim_dom.
DR InterPro; IPR002933; Peptidase_M20.
DR InterPro; IPR011650; Peptidase_M20_dimer.
DR PANTHER; PTHR43808; ACETYLORNITHINE DEACETYLASE; 1.
DR PANTHER; PTHR43808:SF8; M20_DIMER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF07687; M20_dimer; 1.
DR Pfam; PF01546; Peptidase_M20; 1.
DR SUPFAM; SSF55031; Bacterial exopeptidase dimerisation domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS00758; ARGE_DAPE_CPG2_1; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000008243};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 167..254
FT /note="Peptidase M20 dimerisation"
FT /evidence="ECO:0000259|Pfam:PF07687"
SQ SEQUENCE 364 AA; 38380 MW; F243615D71426ED3 CRC64;
MDELRDLTET LVSVPSHEDE TAAGDAIEAW LREETDADVA RDDAGNVVAR VNPGVGESLA
LVGHHDVVPP ADRQTTDSGD YVVETRDGRL YGRGAADMKG AVAASMLAFR DAAADADSEV
AFASFVGEEI GGEGVRAALD DGFELDYAVV AEGSTNYSGP NRTDVAVAHR GRRASTLVAS
GTACHASGPE RGENAVYRAT DAVDVVRGLS VPDAEVLDHP VSGSIAVTEI DGGSAWNVIP
DRCEVTLDER TVPGGFADLA RTAELEGVEW VVEQDLPPMA CDDADFAERV LDAARSVHEA
RSDAEPEQTT KPHATDAGWL AQAGTTCVVY GPSEPGEAHT KDESVSLDVL ARCYETYRAL
VANW
//
