ID   D4GX06_HALVD            Unreviewed;       530 AA.
AC   D4GX06; L9UVB3;
DT   18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT   18-MAY-2010, sequence version 1.
DT   27-MAR-2024, entry version 64.
DE   SubName: Full=Xanthine/uracil permease family transport protein {ECO:0000313|EMBL:ADE04493.1};
GN   Name=uraA1 {ECO:0000313|EMBL:ADE04493.1};
GN   OrderedLocusNames=HVO_1227 {ECO:0000313|EMBL:ADE04493.1};
OS   Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 /
OS   NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC   Haloferacaceae; Haloferax.
OX   NCBI_TaxID=309800 {ECO:0000313|EMBL:ADE04493.1, ECO:0000313|Proteomes:UP000008243};
RN   [1] {ECO:0000313|EMBL:ADE04493.1, ECO:0000313|Proteomes:UP000008243}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 /
RC   VKM B-1768 / DS2 {ECO:0000313|Proteomes:UP000008243};
RX   PubMed=20333302; DOI=10.1371/journal.pone.0009605;
RA   Hartman A.L., Norais C., Badger J.H., Delmas S., Haldenby S., Madupu R.,
RA   Robinson J., Khouri H., Ren Q., Lowe T.M., Maupin-Furlow J.,
RA   Pohlschroder M., Daniels C., Pfeiffer F., Allers T., Eisen J.A.;
RT   "The complete genome sequence of Haloferax volcanii DS2, a model
RT   archaeon.";
RL   PLoS ONE 5:E9605-E9605(2010).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; CP001956; ADE04493.1; -; Genomic_DNA.
DR   RefSeq; WP_004043715.1; NZ_AOHU01000091.1.
DR   AlphaFoldDB; D4GX06; -.
DR   STRING; 309800.HVO_1227; -.
DR   PaxDb; 309800-C498_12613; -.
DR   EnsemblBacteria; ADE04493; ADE04493; HVO_1227.
DR   GeneID; 8925518; -.
DR   KEGG; hvo:HVO_1227; -.
DR   PATRIC; fig|309800.29.peg.2415; -.
DR   eggNOG; arCOG02805; Archaea.
DR   HOGENOM; CLU_017959_5_4_2; -.
DR   OrthoDB; 76842at2157; -.
DR   Proteomes; UP000008243; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR   InterPro; IPR006043; NCS2.
DR   PANTHER; PTHR11119:SF3; LD30822P; 1.
DR   PANTHER; PTHR11119; XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER; 1.
DR   Pfam; PF00860; Xan_ur_permease; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008243};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        34..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        58..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        89..108
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        120..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        148..166
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        178..195
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        207..232
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        361..384
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        390..410
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        422..445
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        465..488
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   530 AA;  54789 MW;  6AD6EF7B9B167B2D CRC64;
     MVVTDDSSPS SFVQYGIDDK PPLPTALLLG AQHYLTMVGA NIAVPLILAG ALGMPADVIP
     RFVGTFFVVS GIATLMQTTF GNRYPIVQGA PFSMLAPALA VIGVATAADQ SGVAWQSALL
     QLQGAIIVAA VVEVFVGYFG LLGRLRKFIS PVVIAPTIAL IGLSLFNAPQ VASATNNWWL
     LGLTLALIVL FSQYLDTAHP AFKLFPVLLG VIVSYVVAAG LSVAGVIAPG AAGYVNLQTV
     IEAPALMPIY PLQWGFAGGA GTTTVSLPVV GSVAFGIPQF TTSFIIGMLA GVAASMVESF
     GDYHAVARLS GVGAPSERRI NHGIGMEGAM NVFSAVMGGS GSTSYSENIG AIGLTGVASR
     YVVQVGAVVM LVMGFVGYFG QLIATIPDPI VGGLYVAMFG QIVAVGLSNL KYVDLDSSRN
     VFIVGVTMFA GLAVPAYMGN VGSAAAFREG MRQVALVGPV LGTQLVADTV FVIGSTGMAV
     GGLIAFFFDN TIAGTRAERG LEEWEDTVED DDDFESALDR FRGDESATAD
//