ID D4GXN3_HALVD Unreviewed; 784 AA.
AC D4GXN3;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=DNA repair helicase Rad3 {ECO:0000313|EMBL:ADE04644.1};
DE EC=3.6.4.12 {ECO:0000313|EMBL:ADE04644.1};
GN Name=rad3a {ECO:0000313|EMBL:ADE04644.1};
GN OrderedLocusNames=HVO_1351 {ECO:0000313|EMBL:ADE04644.1};
OS Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 /
OS NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii).
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Haloferacaceae; Haloferax.
OX NCBI_TaxID=309800 {ECO:0000313|EMBL:ADE04644.1, ECO:0000313|Proteomes:UP000008243};
RN [1] {ECO:0000313|EMBL:ADE04644.1, ECO:0000313|Proteomes:UP000008243}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 /
RC VKM B-1768 / DS2 {ECO:0000313|Proteomes:UP000008243};
RX PubMed=20333302; DOI=10.1371/journal.pone.0009605;
RA Hartman A.L., Norais C., Badger J.H., Delmas S., Haldenby S., Madupu R.,
RA Robinson J., Khouri H., Ren Q., Lowe T.M., Maupin-Furlow J.,
RA Pohlschroder M., Daniels C., Pfeiffer F., Allers T., Eisen J.A.;
RT "The complete genome sequence of Haloferax volcanii DS2, a model
RT archaeon.";
RL PLoS ONE 5:E9605-E9605(2010).
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DR EMBL; CP001956; ADE04644.1; -; Genomic_DNA.
DR RefSeq; WP_013035586.1; NZ_AOHU01000091.1.
DR AlphaFoldDB; D4GXN3; -.
DR STRING; 309800.HVO_1351; -.
DR PaxDb; 309800-C498_11983; -.
DR EnsemblBacteria; ADE04644; ADE04644; HVO_1351.
DR GeneID; 8925852; -.
DR KEGG; hvo:HVO_1351; -.
DR eggNOG; arCOG00770; Archaea.
DR HOGENOM; CLU_313456_0_0_2; -.
DR OrthoDB; 27512at2157; -.
DR Proteomes; UP000008243; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR006555; ATP-dep_Helicase_C.
DR InterPro; IPR045028; DinG/Rad3-like.
DR InterPro; IPR014013; Helic_SF1/SF2_ATP-bd_DinG/Rad3.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010614; RAD3-like_helicase_DEAD.
DR PANTHER; PTHR11472:SF65; DNA HELICASE REPD; 1.
DR PANTHER; PTHR11472; DNA REPAIR DEAD HELICASE RAD3/XP-D SUBFAMILY MEMBER; 1.
DR Pfam; PF06733; DEAD_2; 1.
DR Pfam; PF13307; Helicase_C_2; 1.
DR SMART; SM00491; HELICc2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51193; HELICASE_ATP_BIND_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:ADE04644.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:ADE04644.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008243}.
FT DOMAIN 11..376
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51193"
FT REGION 162..195
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 388..408
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 342..376
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 784 AA; 85835 MW; 0435EE8EC7ED03D7 CRC64;
MAVATGPQSV TWQEVFGHPE AYPEQADGIE TAIQTARDDG FAVVEGACGT GKTMLALTAG
IDLVRDPDSD YERVFVLTSV KQQLRQFEAD LRTINENLPT DWTPVSGLTL VGKSDVCPYS
REGCGGIDDA TVYDRCEALR DRTRGLVGDG GRTSAEALAK DAREQQTGLL DTGSTAAGPD
YLETAGDPTP YPTSMPEYED VEYCPFYANF LADLPEDGDP IEAVPFDFDD KGLIGTEDLV
SLAAGAGSCP HSVMGALLPH VEVVVGNYYH AFDPTTVGTF TGALVDDSTF VICDEAHMLE
PRVRDLVSVG VGDRTLRDAE SEFTRVIQPV KFDDAGKSTV DADLVRGELQ EADVTLRELE
ETRDFIRDLR EELDRRVTAH LDREYGGWRA DPTELDDEEL PLRDPEEPGV DELTEWAEER
GHDEGTWVRA EATGSAVARI LDSVEEDDKR RAAPAAGRAL STWAYADHEK HFREIELERT
WDEMEPPESW RRAYNARLSV HNCVPGEAIA ERLGDFGGGV LMSATLEPID VFRRVTGLDA
LADDGRPVAE RTFGLGFPES NRASFAVDVP KFTHSNRGPP GEENETRLAY TDAAVEVCER
SPGNVLVGMP NYAEAEWMAG ALEARVDKPV LLDESSDDGA TERLKRDFFG GEGKVLVTSL
RGTLTEGVDY SGDKLSAAVV CGVPLINTSS PRTRAVKTAY DREFGDGFET ALTVPAVRKA
RQAIGRVIRG TDEVGVRVFV DARYARDSWN GVRDYLPAQE REEFRPVSPD MLGFGLDQFW
SSAE
//
