ID D4H1V0_DENA2 Unreviewed; 647 AA.
AC D4H1V0;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Diguanylate cyclase/phosphodiesterase with extracellular sensor {ECO:0000313|EMBL:ADD66927.1};
GN OrderedLocusNames=Dacet_0121 {ECO:0000313|EMBL:ADD66927.1};
OS Denitrovibrio acetiphilus (strain DSM 12809 / NBRC 114555 / N2460).
OC Bacteria; Deferribacterota; Deferribacteres; Deferribacterales;
OC Geovibrionaceae; Denitrovibrio.
OX NCBI_TaxID=522772 {ECO:0000313|EMBL:ADD66927.1, ECO:0000313|Proteomes:UP000002012};
RN [1] {ECO:0000313|EMBL:ADD66927.1, ECO:0000313|Proteomes:UP000002012}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12809 / NBRC 114555 / N2460
RC {ECO:0000313|Proteomes:UP000002012};
RX PubMed=21304711; DOI=10.4056/sigs.892105;
RA Kiss H., Lang E., Lapidus A., Copeland A., Nolan M., Glavina Del Rio T.,
RA Chen F., Lucas S., Tice H., Cheng J.F., Han C., Goodwin L., Pitluck S.,
RA Liolios K., Pati A., Ivanova N., Mavromatis K., Chen A., Palaniappan K.,
RA Land M., Hauser L., Chang Y.J., Jeffries C.D., Detter J.C., Brettin T.,
RA Spring S., Rohde M., Goker M., Woyke T., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Denitrovibrio acetiphilus type strain
RT (N2460).";
RL Stand. Genomic Sci. 2:270-279(2010).
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DR EMBL; CP001968; ADD66927.1; -; Genomic_DNA.
DR RefSeq; WP_013009475.1; NC_013943.1.
DR AlphaFoldDB; D4H1V0; -.
DR STRING; 522772.Dacet_0121; -.
DR PaxDb; 522772-Dacet_0121; -.
DR KEGG; dap:Dacet_0121; -.
DR eggNOG; COG2199; Bacteria.
DR eggNOG; COG2200; Bacteria.
DR HOGENOM; CLU_000445_109_1_0; -.
DR InParanoid; D4H1V0; -.
DR OrthoDB; 9777298at2; -.
DR Proteomes; UP000002012; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd01948; EAL; 1.
DR Gene3D; 3.30.110.200; -; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 6.20.270.20; LapD/MoxY periplasmic domain; 1.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR032244; LapD_MoxY_N.
DR InterPro; IPR042461; LapD_MoxY_peri_C.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR PANTHER; PTHR33121; CYCLIC DI-GMP PHOSPHODIESTERASE PDEF; 1.
DR PANTHER; PTHR33121:SF32; RNASE E SPECIFICITY FACTOR CSRD; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF16448; LapD_MoxY_N; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50885; HAMP; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002012};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..27
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 170..222
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 264..398
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 407..647
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 647 AA; 72164 MW; 0057024CDDAECB43 CRC64;
MTLFRQIQIF VTLLLVVMLI VVLKINFDST REFVRTQLYS DAKNTANSLS LSLSTVAGDE
AAMVTMMRAM FDGGYYEEIK LINAEGKVIG DISQKPVIEG VPGFFIRMVD FENIPAEAQI
SSGWTIFGTL SVKGHPGLSY IRLWDSFKYL GMWFVIIGLS ALAATHMALR LIFRPLGAVR
EQAAAIENNE FIINKNIPST PEMKQVVITM NSMVSKAQAI YNREIETLKN YQELLYKDQS
TGLFNRKYFV SQLSAYLQAE NENSSGEVVI LSFEGMEDAA AEAGHSVISK LFSFCVDEMQ
SISGKVPNSV PACLNNREFA LILPGCDTAE ALVMAKTATD NINNYIKSIE EIKDILGVFC
GAASYRYDED MGKVLSKVDY AVTLAKSKES GAVERYVDDG SHIVLGKMEW KHMIETALGE
DRFILTSQPV VSDGGELHQE IYVNMVDSDG KVQRAGFFMP MVISLNLANS LDRYVLEKTV
DYLTGNKEHT LAINITDMFL NDRGAFSWFR KLLVSAKHLR ERLTFEISDS AIKHHLDICL
DFSGLIKGLG FTFGVDRFAM SQESLENLQQ LKPDYLKVDY DYLINSEDGD VAAALKSLQT
ITDSLGIKLI ATKIDSEELR QKLEDNNIKY FQGRGVAGIN PLGKNNE
//
