ID D4H8N4_DENA2 Unreviewed; 409 AA.
AC D4H8N4;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Phosphoglycerate mutase {ECO:0000313|EMBL:ADD68383.1};
DE Flags: Precursor;
GN OrderedLocusNames=Dacet_1617 {ECO:0000313|EMBL:ADD68383.1};
OS Denitrovibrio acetiphilus (strain DSM 12809 / NBRC 114555 / N2460).
OC Bacteria; Deferribacterota; Deferribacteres; Deferribacterales;
OC Geovibrionaceae; Denitrovibrio.
OX NCBI_TaxID=522772 {ECO:0000313|EMBL:ADD68383.1, ECO:0000313|Proteomes:UP000002012};
RN [1] {ECO:0000313|EMBL:ADD68383.1, ECO:0000313|Proteomes:UP000002012}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 12809 / NBRC 114555 / N2460
RC {ECO:0000313|Proteomes:UP000002012};
RX PubMed=21304711; DOI=10.4056/sigs.892105;
RA Kiss H., Lang E., Lapidus A., Copeland A., Nolan M., Glavina Del Rio T.,
RA Chen F., Lucas S., Tice H., Cheng J.F., Han C., Goodwin L., Pitluck S.,
RA Liolios K., Pati A., Ivanova N., Mavromatis K., Chen A., Palaniappan K.,
RA Land M., Hauser L., Chang Y.J., Jeffries C.D., Detter J.C., Brettin T.,
RA Spring S., Rohde M., Goker M., Woyke T., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Denitrovibrio acetiphilus type strain
RT (N2460).";
RL Stand. Genomic Sci. 2:270-279(2010).
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DR EMBL; CP001968; ADD68383.1; -; Genomic_DNA.
DR RefSeq; WP_013010897.1; NC_013943.1.
DR AlphaFoldDB; D4H8N4; -.
DR STRING; 522772.Dacet_1617; -.
DR PaxDb; 522772-Dacet_1617; -.
DR KEGG; dap:Dacet_1617; -.
DR eggNOG; COG0406; Bacteria.
DR HOGENOM; CLU_006383_1_1_0; -.
DR InParanoid; D4H8N4; -.
DR OrthoDB; 4697614at2; -.
DR Proteomes; UP000002012; Chromosome.
DR GO; GO:0003873; F:6-phosphofructo-2-kinase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IEA:InterPro.
DR GO; GO:0006000; P:fructose metabolic process; IEA:InterPro.
DR CDD; cd07067; HP_PGM_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.1240; Phosphoglycerate mutase-like; 1.
DR InterPro; IPR003094; 6Pfruct_kin.
DR InterPro; IPR013079; 6Phosfructo_kin.
DR InterPro; IPR013078; His_Pase_superF_clade-1.
DR InterPro; IPR029033; His_PPase_superfam.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10606:SF44; 6-PHOSPHOFRUCTO 2-KINASE_FRUCTOSE 2,6-BISPHOSPHATASE LONG FORM; 1.
DR PANTHER; PTHR10606; 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE; 1.
DR Pfam; PF01591; 6PF2K; 1.
DR Pfam; PF00300; His_Phos_1; 1.
DR PIRSF; PIRSF000709; 6PFK_2-Ptase; 1.
DR PRINTS; PR00991; 6PFRUCTKNASE.
DR SMART; SM00855; PGAM; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF53254; Phosphoglycerate mutase-like; 1.
PE 4: Predicted;
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002012}.
FT DOMAIN 3..176
FT /note="6-phosphofructo-2-kinase"
FT /evidence="ECO:0000259|Pfam:PF01591"
FT BINDING 217..224
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-2"
FT BINDING 265
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR613078-2"
SQ SEQUENCE 409 AA; 48061 MW; 5B5C4A9EC6E024D4 CRC64;
MQTKERKKLC IAMMGLPARG KSTHAKKILE NLSKENLNVR IFNNGDLRRK YIKENTASFE
FYNPDNHKAV KIRENIALVN IRDARDFLNG IGHIAIIDAA NVTSNRRQTI IEEMSDYNIL
FIECVNEQED FLKICIDTKT ELLEFSHLPK EEATQNFLKR IEYYKSRYDN LTDEPNYIVI
DSLNNKIIRE KDAGIPYYHL IRDILVSGWI HNLYLVRHGQ TYFNLDNRIG GDSELTERGI
RQGADLAKHF RNTDIHYIFT STKKRTMAIA YEIKKEIPDV EIVPFEEFDE INTGDCDSIT
YDELRLNFPE LYEARSKDKY NFTYPNGESY RTMRERVQFG LKKALFLSGG AENIVIIGHR
GVNRIILSLF EFRDVEDVPY IYIPQDKYFQ ITATQYKKLI EMKKFTEFD
//
