ID D4HW92_ERWAC Unreviewed; 333 AA.
AC D4HW92;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=UTP--glucose-1-phosphate uridylyltransferase {ECO:0000256|ARBA:ARBA00019048};
DE EC=2.7.7.9 {ECO:0000256|ARBA:ARBA00012415};
DE AltName: Full=Alpha-D-glucosyl-1-phosphate uridylyltransferase {ECO:0000256|ARBA:ARBA00031455};
DE AltName: Full=UDP-glucose pyrophosphorylase {ECO:0000256|ARBA:ARBA00031959};
DE AltName: Full=Uridine diphosphoglucose pyrophosphorylase {ECO:0000256|ARBA:ARBA00032341};
GN Name=galF {ECO:0000313|EMBL:CBA21335.1};
GN OrderedLocusNames=EAMY_2241 {ECO:0000313|EMBL:CBA21335.1};
OS Erwinia amylovora (strain CFBP1430).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Erwiniaceae; Erwinia.
OX NCBI_TaxID=665029 {ECO:0000313|EMBL:CBA21335.1, ECO:0000313|Proteomes:UP000001841};
RN [1] {ECO:0000313|EMBL:CBA21335.1, ECO:0000313|Proteomes:UP000001841}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CFBP1430 {ECO:0000313|Proteomes:UP000001841};
RX PubMed=20192826; DOI=10.1094/MPMI-23-4-0384;
RA Smits T.H., Rezzonico F., Kamber T., Blom J., Goesmann A., Frey J.E.,
RA Duffy B.;
RT "Complete genome sequence of the fire blight pathogen Erwinia amylovora
RT CFBP 1430 and comparison to other Erwinia spp.";
RL Mol. Plant Microbe Interact. 23:384-393(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-
CC alpha-D-glucose; Xref=Rhea:RHEA:19889, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:46398, ChEBI:CHEBI:58601,
CC ChEBI:CHEBI:58885; EC=2.7.7.9;
CC Evidence={ECO:0000256|ARBA:ARBA00000872};
CC -!- SIMILARITY: Belongs to the UDPGP type 2 family.
CC {ECO:0000256|ARBA:ARBA00006890}.
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DR EMBL; FN434113; CBA21335.1; -; Genomic_DNA.
DR AlphaFoldDB; D4HW92; -.
DR STRING; 665029.EAMY_2241; -.
DR KEGG; eam:EAMY_2241; -.
DR eggNOG; COG1210; Bacteria.
DR HOGENOM; CLU_029499_1_2_6; -.
DR Proteomes; UP000001841; Chromosome.
DR GO; GO:0003983; F:UTP:glucose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR GO; GO:0006011; P:UDP-glucose metabolic process; IEA:InterPro.
DR CDD; cd02541; UGPase_prokaryotic; 1.
DR InterPro; IPR005771; GalU_uridylyltTrfase_bac/arc.
DR InterPro; IPR005835; NTP_transferase_dom.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR43197; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR43197:SF2; UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR Pfam; PF00483; NTP_transferase; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000313|EMBL:CBA21335.1};
KW Transferase {ECO:0000313|EMBL:CBA21335.1}.
FT DOMAIN 40..308
FT /note="Nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF00483"
SQ SEQUENCE 333 AA; 37019 MW; B9C091967BBD65A8 CRC64;
MVEARCIFFG LRLYLRIISL MHNEFVFQHH SYGKIMTKLK AVIPVAGLGM HMLPATKAIP
KEMLPVVDKP MIQYIIDECV AAGIKEIVLV THASKNAVEN HFDTSYELEA LLEARVKRSL
LSEVKSICPP GVTIMNVRQP QPLGLANALL CARPMLHDEA FVVVLPDVLL DNASADPLRY
NLAAMVARFE ETGRSQVLAH HMPDADLSEY SVITTEEPLD FPGKVSSILE FVEKPENPEA
LNSDLAAVGR YVLSADIWPE LEALEPGAWG RYQLTDAIVS LNKKTPVDAQ LLSGDSFDCG
RKLGYMKAFV TWGLRNHSQG RAFRDEIQKI LAK
//
