ID D4JFJ6_9FIRM Unreviewed; 503 AA.
AC D4JFJ6;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Predicted metal-dependent phosphoesterases (PHP family) {ECO:0000313|EMBL:CBK88968.1};
GN ORFNames=EC1_16590 {ECO:0000313|EMBL:CBK88968.1};
OS Faecalitalea cylindroides T2-87.
OC Bacteria; Bacillota; Erysipelotrichia; Erysipelotrichales;
OC Erysipelotrichaceae; Faecalitalea.
OX NCBI_TaxID=717960 {ECO:0000313|EMBL:CBK88968.1, ECO:0000313|Proteomes:UP000008801};
RN [1] {ECO:0000313|EMBL:CBK88968.1, ECO:0000313|Proteomes:UP000008801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T2-87 {ECO:0000313|EMBL:CBK88968.1,
RC ECO:0000313|Proteomes:UP000008801};
RG metaHIT consortium -- http://www.metahit.eu/;
RA Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT "The genome sequence of Eubacterium cylindroides T2-87.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBK88968.1, ECO:0000313|Proteomes:UP000008801}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T2-87 {ECO:0000313|EMBL:CBK88968.1,
RC ECO:0000313|Proteomes:UP000008801};
RA Pajon A.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FP929041; CBK88968.1; -; Genomic_DNA.
DR AlphaFoldDB; D4JFJ6; -.
DR STRING; 717960.EC1_16590; -.
DR KEGG; euc:EC1_16590; -.
DR PATRIC; fig|717960.3.peg.1148; -.
DR HOGENOM; CLU_498538_0_0_9; -.
DR Proteomes; UP000008801; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd07438; PHP_HisPPase_AMP; 1.
DR Gene3D; 1.10.150.650; -; 1.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR InterPro; IPR004013; PHP_dom.
DR InterPro; IPR003141; Pol/His_phosphatase_N.
DR InterPro; IPR016195; Pol/histidinol_Pase-like.
DR InterPro; IPR010432; RDD.
DR PANTHER; PTHR42924; EXONUCLEASE; 1.
DR PANTHER; PTHR42924:SF3; POLIIIAC DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02811; PHP; 1.
DR Pfam; PF06271; RDD; 1.
DR SMART; SM00481; POLIIIAc; 1.
DR SUPFAM; SSF89550; PHP domain-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 45..75
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..162
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 211..277
FT /note="Polymerase/histidinol phosphatase N-terminal"
FT /evidence="ECO:0000259|SMART:SM00481"
SQ SEQUENCE 503 AA; 57240 MW; 7D0AC3AEBB91C088 CRC64;
MDVKKYNIKD LTLAYFNKKS QIYRSGGYKQ ARVLTRDKED YINHFFAFLI DINICLLPVY
IWVIEFLLIL CGLISPHFFD LLFYIMYGCL FVVSVLLLGL FTARSKGQSF GYVLTDLKLV
RRDKREAMAL NLIMRQALGI GIPLMILGYF FGTPGILAWW LLNGIIVLIT PNQQSLFDLV
FGLVTVNEPE INITFDNKKP EPKVQHDICP IDLHIRSNYS DDGYYDVEEI FKQAKQLKME
VISITDHNCA RANAAATRFA ELYGIQYIPG VELDAQYNGT RVRVLGYYID WTKDIFEILE
SDSLLREKEC SIQRVKKFEE FSGISIDVDS IISNSRFQTI TATDITKMVF NNERVRSMSF
VKRYIDQAST QSEAMARFKR DLFGKGGPCY VKGNYPELDS AIEAIHQAGG IAILSSWQLD
NISDEMIERM ISLGIDGVEV FSPNVHDETI AAVLKIVQKY KLLVSCGSDY HGPTKPNRRL
GETNCPEKGL ALVKILTKAA KKD
//
