ID D4JXG3_9FIRM Unreviewed; 487 AA.
AC D4JXG3;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=FP2_11810 {ECO:0000313|EMBL:CBK98712.1};
OS Faecalibacterium prausnitzii L2-6.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Faecalibacterium.
OX NCBI_TaxID=718252 {ECO:0000313|EMBL:CBK98712.1, ECO:0000313|Proteomes:UP000008804};
RN [1] {ECO:0000313|EMBL:CBK98712.1, ECO:0000313|Proteomes:UP000008804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L2-6 {ECO:0000313|Proteomes:UP000008804};
RG metaHIT consortium -- http://www.metahit.eu/;
RA Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT "The genome sequence of Faecalibacterium prausnitzii L2/6.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBK98712.1, ECO:0000313|Proteomes:UP000008804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L2-6 {ECO:0000313|Proteomes:UP000008804};
RA Pajon A.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FP929045; CBK98712.1; -; Genomic_DNA.
DR AlphaFoldDB; D4JXG3; -.
DR STRING; 718252.FP2_11810; -.
DR KEGG; fpr:FP2_11810; -.
DR PATRIC; fig|718252.3.peg.2526; -.
DR eggNOG; COG2205; Bacteria.
DR eggNOG; COG3452; Bacteria.
DR HOGENOM; CLU_559905_0_0_9; -.
DR BioCyc; FPRA718252:G1375-996-MONOMER; -.
DR Proteomes; UP000008804; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.350; CHASE domain; 1.
DR InterPro; IPR006189; CHASE_dom.
DR InterPro; IPR042240; CHASE_sf.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR PANTHER; PTHR43047:SF72; OSMOSENSING HISTIDINE PROTEIN KINASE SLN1; 1.
DR PANTHER; PTHR43047; TWO-COMPONENT HISTIDINE PROTEIN KINASE; 1.
DR Pfam; PF03924; CHASE; 1.
DR Pfam; PF00512; HisKA; 1.
DR SMART; SM01079; CHASE; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50839; CHASE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000008804};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 108..195
FT /note="CHASE"
FT /evidence="ECO:0000259|PROSITE:PS50839"
SQ SEQUENCE 487 AA; 54596 MW; 6119A4977A323634 CRC64;
MALKKFARRD VILPAAVFLL TFAAALFSLR LLSLNQEKDE RLRAVYAAES TISRVSSQLN
RYLAESNFIK KYIEAGHVLR EEEFAGISGN MRDGSSVIKT HELAKDGVVS QVYPVAGNEA
AIGLDVLHNP ARKKEANLAR NSGMYTIAGP FELVQGGTGA LLFDPIYTYS KKGERSFWGF
SILVLQWDNF MEEVELDKME DAGYRYQIWK KDTYTGEKIV IAESEEDFPG NALEVACSVP
NDTWYFEIIP KAGWFSDQQL SLDIAIAAII GMMAAYACWE LMNRHRKDLQ HEAALEKSAQ
EARAANEAKT RFLFNMSHDI RTPMNAIIGF SELLEKHIDE KDRVLDYTEK IRSSSAFLLS
LINYVLEMAR IESGKAVLKE ETGDLCADAD ALGRLRALCP AEKADLHLPY GYRTSLYCER
PHQSAGDLVE CHQQRHQVYA RGRTYCGVGE GTAGGGAEDG PLYLYRSGRR HRHERGVSAP
YLRGVHP
//
