ID D4JXL4_9FIRM Unreviewed; 505 AA.
AC D4JXL4;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 24-JAN-2024, entry version 50.
DE SubName: Full=Amino acid carrier protein {ECO:0000313|EMBL:CBK98763.1};
GN ORFNames=FP2_12380 {ECO:0000313|EMBL:CBK98763.1};
OS Faecalibacterium prausnitzii L2-6.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Faecalibacterium.
OX NCBI_TaxID=718252 {ECO:0000313|EMBL:CBK98763.1, ECO:0000313|Proteomes:UP000008804};
RN [1] {ECO:0000313|EMBL:CBK98763.1, ECO:0000313|Proteomes:UP000008804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L2-6 {ECO:0000313|Proteomes:UP000008804};
RG metaHIT consortium -- http://www.metahit.eu/;
RA Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT "The genome sequence of Faecalibacterium prausnitzii L2/6.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBK98763.1, ECO:0000313|Proteomes:UP000008804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L2-6 {ECO:0000313|Proteomes:UP000008804};
RA Pajon A.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC ECO:0000256|RuleBase:RU363064}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FP929045; CBK98763.1; -; Genomic_DNA.
DR AlphaFoldDB; D4JXL4; -.
DR KEGG; fpr:FP2_12380; -.
DR PATRIC; fig|718252.3.peg.2597; -.
DR eggNOG; COG1115; Bacteria.
DR HOGENOM; CLU_024867_1_2_9; -.
DR BioCyc; FPRA718252:G1375-1049-MONOMER; -.
DR Proteomes; UP000008804; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR InterPro; IPR001463; Na/Ala_symport.
DR NCBIfam; TIGR00835; agcS; 1.
DR PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR PANTHER; PTHR30330:SF3; TRANSCRIPTIONAL REGULATOR, LRP FAMILY-RELATED; 1.
DR Pfam; PF01235; Na_Ala_symp; 1.
DR PRINTS; PR00175; NAALASMPORT.
DR PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW ECO:0000256|RuleBase:RU363064};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW Reference proteome {ECO:0000313|Proteomes:UP000008804};
KW Symport {ECO:0000256|RuleBase:RU363064};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU363064};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU363064};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT TRANSMEM 15..34
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 79..99
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 105..130
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 159..179
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 199..217
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 229..249
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 255..278
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 323..344
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 364..390
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 411..432
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
FT TRANSMEM 438..460
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU363064"
SQ SEQUENCE 505 AA; 53701 MW; 56B2AEDAB6803311 CRC64;
MVDIVTRVNN VVNGFVWGPF GLALLFCTGL WLSVRTGFFQ FRRMGYWLRH TIGAIFTNKD
VTAHTSKEDM AISQFQSMCT ALAGTIGTGN IVGVATAIVS GGPGAIFWMW VMALLGMMTS
FAENVLGVYY RRKNEKGEWN GGAMYYLTDG LGAKPGCRAV GRVLAVLFSC FCILASFGIG
NMSQINSIAG NMNAAFHLPY LATGLALMVV TALIVIGGLK RVAAVTEKLV PLMALFYVAG
ALIIVVMHAG NIPAAVAAIF KGAFNLNAAG GGALGYGISQ TITWGFKRGA FSNEAGLGSA
VMVNSASNVK EPVHQGMWGV FEVFADTIVV CTLTALVILT TGVVDLESGA VLAGVQDNAL
VGQAFTAAFG SFGPKFIAVS ILLFAYSTTL GWSHYGTKAV EYLFGTAGSR IYKVVFVCMT
VVGATMKLGL AWDLSDTFNG LMMIPNLIGV LALSGTVVDI TKNYFARRVR GEDIEPMWSA
FEEYQKEEEA EAAAEKAELE KAANK
//
