ID   D4JZH1_9FIRM            Unreviewed;       442 AA.
AC   D4JZH1;
DT   18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT   18-MAY-2010, sequence version 1.
DT   24-JAN-2024, entry version 65.
DE   RecName: Full=serine--tRNA ligase {ECO:0000256|ARBA:ARBA00012840};
DE            EC=6.1.1.11 {ECO:0000256|ARBA:ARBA00012840};
DE   AltName: Full=Seryl-tRNA synthetase {ECO:0000256|ARBA:ARBA00031113};
GN   ORFNames=FP2_20240 {ECO:0000313|EMBL:CBK99420.1};
OS   Faecalibacterium prausnitzii L2-6.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Faecalibacterium.
OX   NCBI_TaxID=718252 {ECO:0000313|EMBL:CBK99420.1, ECO:0000313|Proteomes:UP000008804};
RN   [1] {ECO:0000313|EMBL:CBK99420.1, ECO:0000313|Proteomes:UP000008804}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L2-6 {ECO:0000313|Proteomes:UP000008804};
RG   metaHIT consortium -- http://www.metahit.eu/;
RA   Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT   "The genome sequence of Faecalibacterium prausnitzii L2/6.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CBK99420.1, ECO:0000313|Proteomes:UP000008804}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L2-6 {ECO:0000313|Proteomes:UP000008804};
RA   Pajon A.;
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FP929045; CBK99420.1; -; Genomic_DNA.
DR   AlphaFoldDB; D4JZH1; -.
DR   STRING; 718252.FP2_20240; -.
DR   KEGG; fpr:FP2_20240; -.
DR   PATRIC; fig|718252.3.peg.202; -.
DR   eggNOG; COG0172; Bacteria.
DR   HOGENOM; CLU_023797_0_1_9; -.
DR   BioCyc; FPRA718252:G1375-1714-MONOMER; -.
DR   Proteomes; UP000008804; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0004828; F:serine-tRNA ligase activity; IEA:UniProtKB-EC.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProt.
DR   GO; GO:0006434; P:seryl-tRNA aminoacylation; IEA:InterPro.
DR   Gene3D; 1.10.287.40; Serine-tRNA synthetase, tRNA binding domain; 1.
DR   InterPro; IPR002314; aa-tRNA-synt_IIb.
DR   InterPro; IPR006195; aa-tRNA-synth_II.
DR   InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR   InterPro; IPR002317; Ser-tRNA-ligase_type_1.
DR   InterPro; IPR015866; Ser-tRNA-synth_1_N.
DR   InterPro; IPR042103; SerRS_1_N_sf.
DR   InterPro; IPR010978; tRNA-bd_arm.
DR   NCBIfam; TIGR00414; serS; 1.
DR   PANTHER; PTHR11778:SF7; SERINE--TRNA LIGASE, CYTOPLASMIC-RELATED; 1.
DR   PANTHER; PTHR11778; SERYL-TRNA SYNTHETASE; 1.
DR   Pfam; PF02403; Seryl_tRNA_N; 1.
DR   Pfam; PF00587; tRNA-synt_2b; 1.
DR   PIRSF; PIRSF001529; Ser-tRNA-synth_IIa; 1.
DR   PRINTS; PR00981; TRNASYNTHSER.
DR   SUPFAM; SSF55681; Class II aaRS and biotin synthetases; 1.
DR   SUPFAM; SSF46589; tRNA-binding arm; 1.
DR   PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE   4: Predicted;
KW   Aminoacyl-tRNA synthetase {ECO:0000256|ARBA:ARBA00023146,
KW   ECO:0000313|EMBL:CBK99420.1}; ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:CBK99420.1};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Protein biosynthesis {ECO:0000256|ARBA:ARBA00022917};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008804}.
FT   DOMAIN          154..423
FT                   /note="Aminoacyl-transfer RNA synthetases class-II family
FT                   profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50862"
FT   COILED          91..118
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   442 AA;  50015 MW;  713E8931CF5CE6C1 CRC64;
     MLDIKFVRDN PDAVKENIKK KFQDAKLPLV DEVIEKDAKY RECLKEVETL KAARNKLSKA
     NGPLFGQLKK CDDEAKKAEL QAQIDANNAA VKADADKMAE LEAEEAKLAE RIQEIMYTIP
     QMIDPSVPIG PDDTYNVEAQ RFGEPVVPDF PIPYHTEIME SFDGIDMDAA GRVAGNGFYY
     LLGNIARLHE AVLAYARDFM IDKGFTYVIP PFMMHGNVVQ GVMSFPEMDA MMYKIEGEDL
     YLIGTSEHTM IGRFIDQTLD EAALPLTLTS YSPCFRKEKG AHGIEERGIY RIHQFEKQEM
     IVVCRPEESA DWYEKLWKNS VELFRSMEIP VRQLNCCSGD LADLKVKSCD IEAWSPRQQK
     YFEVCSCSNL GDAQARRLHI RVKGKDGKTY LAHTLNNTCV APPRMLIAFL ENHLQADGSV
     TIPKVLQPYM GGLEVMVPVH KK
//