ID D4K096_9FIRM Unreviewed; 587 AA.
AC D4K096;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 24-JAN-2024, entry version 65.
DE SubName: Full=ABC-type multidrug transport system, ATPase and permease components {ECO:0000313|EMBL:CBK99695.1};
GN ORFNames=FP2_23650 {ECO:0000313|EMBL:CBK99695.1};
OS Faecalibacterium prausnitzii L2-6.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Faecalibacterium.
OX NCBI_TaxID=718252 {ECO:0000313|EMBL:CBK99695.1, ECO:0000313|Proteomes:UP000008804};
RN [1] {ECO:0000313|EMBL:CBK99695.1, ECO:0000313|Proteomes:UP000008804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L2-6 {ECO:0000313|Proteomes:UP000008804};
RG metaHIT consortium -- http://www.metahit.eu/;
RA Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT "The genome sequence of Faecalibacterium prausnitzii L2/6.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBK99695.1, ECO:0000313|Proteomes:UP000008804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L2-6 {ECO:0000313|Proteomes:UP000008804};
RA Pajon A.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; FP929045; CBK99695.1; -; Genomic_DNA.
DR AlphaFoldDB; D4K096; -.
DR STRING; 718252.FP2_23650; -.
DR KEGG; fpr:FP2_23650; -.
DR PATRIC; fig|718252.3.peg.549; -.
DR eggNOG; COG1132; Bacteria.
DR HOGENOM; CLU_000604_84_9_9; -.
DR BioCyc; FPRA718252:G1375-2005-MONOMER; -.
DR Proteomes; UP000008804; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221:SF397; ABC TRANSPORTER, ATP-BINDING TRANSMEMBRANE PROTEIN; 1.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR Pfam; PF00664; ABC_membrane; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000008804};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 23..48
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 60..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 139..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 164..182
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 258..276
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 22..307
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 338..571
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 587 AA; 64068 MW; 82BF4BA79B73A469 CRC64;
MIRLFQRLLL FSGLQKKRLI RSFLAYLVSS FFEMIPIMAI LTVLTGILKQ LSGGVMPERT
IWISLGIMIV SIAGRIVFVD LSANARTLGS FAFGSEKRME IGERLKRAPM GYFNENRLGD
ITAAVTTTLG DLEQQSVTIM ENVAGGFIHA IVISVWLMIY EWRIGLISLA GLAVALIVYS
LIGKVGRKHA PRRQAAQAGL VTAVLEYVQG MGVVKAFGLA EHTGKAVDTA IEESKEANIV
LEKAFSKMTA LYQTVFKLAR AAILVFAPYL LAGGSITPEK CLLLLVSSFM IYAAVEVAGS
MSSVARAVEA SLDRLDNIMD IPSLDENGAD LVPENFNIEV KNMSFGYGEK EVLHQISLSV
PQGSSCAIVG PSGSGKTTLV GLIARFWDVK EGQITLGGRD VREYTSGSLL KNFAIVFQNV
YLFEDTVENN IRFGRPDASE DEIIAVAKKA CCHDFIMTLP DGYQTTIGEG GSSLSGGEKQ
RISIARAILK DAPIVILDEA TASVDPENEQ ELQKAIRELT KGKTILMIAH RLSTVRTADQ
IIVLENGRIV QRGNHEELMR EDGLYRRFVG MRSRAIGWTL KGGKAYG
//
