ID   D4K0R3_9FIRM            Unreviewed;       340 AA.
AC   D4K0R3;
DT   18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT   18-MAY-2010, sequence version 1.
DT   24-JAN-2024, entry version 54.
DE   SubName: Full=Threonine aldolase {ECO:0000313|EMBL:CBK99862.1};
DE            EC=4.1.2.5 {ECO:0000313|EMBL:CBK99862.1};
GN   ORFNames=FP2_25470 {ECO:0000313|EMBL:CBK99862.1};
OS   Faecalibacterium prausnitzii L2-6.
OC   Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC   Faecalibacterium.
OX   NCBI_TaxID=718252 {ECO:0000313|EMBL:CBK99862.1, ECO:0000313|Proteomes:UP000008804};
RN   [1] {ECO:0000313|EMBL:CBK99862.1, ECO:0000313|Proteomes:UP000008804}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L2-6 {ECO:0000313|Proteomes:UP000008804};
RG   metaHIT consortium -- http://www.metahit.eu/;
RA   Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT   "The genome sequence of Faecalibacterium prausnitzii L2/6.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:CBK99862.1, ECO:0000313|Proteomes:UP000008804}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L2-6 {ECO:0000313|Proteomes:UP000008804};
RA   Pajon A.;
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the threonine aldolase family.
CC       {ECO:0000256|ARBA:ARBA00006966}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FP929045; CBK99862.1; -; Genomic_DNA.
DR   AlphaFoldDB; D4K0R3; -.
DR   STRING; 718252.FP2_25470; -.
DR   KEGG; fpr:FP2_25470; -.
DR   PATRIC; fig|718252.3.peg.736; -.
DR   eggNOG; COG2008; Bacteria.
DR   HOGENOM; CLU_049619_1_0_9; -.
DR   BioCyc; FPRA718252:G1375-2175-MONOMER; -.
DR   Proteomes; UP000008804; Chromosome.
DR   GO; GO:0004793; F:threonine aldolase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   Gene3D; 3.90.1150.10; Aspartate Aminotransferase, domain 1; 1.
DR   Gene3D; 3.40.640.10; Type I PLP-dependent aspartate aminotransferase-like (Major domain); 1.
DR   InterPro; IPR001597; ArAA_b-elim_lyase/Thr_aldolase.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   PANTHER; PTHR48097; L-THREONINE ALDOLASE-RELATED; 1.
DR   PANTHER; PTHR48097:SF5; LOW SPECIFICITY L-THREONINE ALDOLASE; 1.
DR   Pfam; PF01212; Beta_elim_lyase; 1.
DR   SUPFAM; SSF53383; PLP-dependent transferases; 1.
PE   3: Inferred from homology;
KW   Lyase {ECO:0000313|EMBL:CBK99862.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008804}.
FT   DOMAIN          16..293
FT                   /note="Aromatic amino acid beta-eliminating lyase/threonine
FT                   aldolase"
FT                   /evidence="ECO:0000259|Pfam:PF01212"
SQ   SEQUENCE   340 AA;  36992 MW;  CF48A77B27105D7F CRC64;
     MLYFENDYCE GAHPAILQKL TETNFEKVSG YGTDPYCASA KEKIRAACAC PEADVFFISG
     GTQANSIVIA STLRRWEGVV AAATGHVAGH EAGAIEFTGH KVIGLPQKNG KLDAATVEDF
     CKTFYADSNH DHMVFPGMVY ISHPTEYGTL YSKAELEALS AVCHTYHMPL FVDGARLGYA
     LVSEGTDVTL ADLARLTDVF YIGGTKVGAL CGEAVVFPHG APAHFMTMVK QQGALLAKGR
     LMGIQFDVLF TDGLYTRISR NAIETANALK KGLAAKGCRF FMDSPTNQLF VVLENARLTA
     LEGKAKFGFW EKFDDSHTVV RIATSWATKM EEIEQLIALM
//