ID D4K2G7_9FIRM Unreviewed; 378 AA.
AC D4K2G7;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE SubName: Full=Putative GTPases (G3E family) {ECO:0000313|EMBL:CBL00466.1};
GN ORFNames=FP2_32370 {ECO:0000313|EMBL:CBL00466.1};
OS Faecalibacterium prausnitzii L2-6.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Oscillospiraceae;
OC Faecalibacterium.
OX NCBI_TaxID=718252 {ECO:0000313|EMBL:CBL00466.1, ECO:0000313|Proteomes:UP000008804};
RN [1] {ECO:0000313|EMBL:CBL00466.1, ECO:0000313|Proteomes:UP000008804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L2-6 {ECO:0000313|Proteomes:UP000008804};
RG metaHIT consortium -- http://www.metahit.eu/;
RA Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT "The genome sequence of Faecalibacterium prausnitzii L2/6.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBL00466.1, ECO:0000313|Proteomes:UP000008804}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L2-6 {ECO:0000313|Proteomes:UP000008804};
RA Pajon A.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC Evidence={ECO:0000256|ARBA:ARBA00001702};
CC -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC subfamily. {ECO:0000256|ARBA:ARBA00034320}.
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DR EMBL; FP929045; CBL00466.1; -; Genomic_DNA.
DR AlphaFoldDB; D4K2G7; -.
DR STRING; 718252.FP2_32370; -.
DR KEGG; fpr:FP2_32370; -.
DR PATRIC; fig|718252.3.peg.1439; -.
DR eggNOG; COG0523; Bacteria.
DR HOGENOM; CLU_017452_1_3_9; -.
DR BioCyc; FPRA718252:G1375-2794-MONOMER; -.
DR Proteomes; UP000008804; Chromosome.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd03112; CobW-like; 1.
DR Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036627; CobW-likC_sf.
DR InterPro; IPR011629; CobW-like_C.
DR InterPro; IPR003495; CobW/HypB/UreG_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR13748:SF62; COBW DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13748; COBW-RELATED; 1.
DR Pfam; PF02492; cobW; 1.
DR Pfam; PF07683; CobW_C; 1.
DR SMART; SM00833; CobW_C; 1.
DR SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000008804}.
FT DOMAIN 292..376
FT /note="CobW C-terminal"
FT /evidence="ECO:0000259|SMART:SM00833"
FT REGION 213..273
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 378 AA; 41948 MW; CA88AD620FCA41D1 CRC64;
MTKIDIFSGF LGAGKTTLIK KLIKESFAGQ KVVLIENEFG EIGIDGGFLK ESGIQINELN
AGCICCSLVG DFRAALQQVV EQYHPDRIVI EPSGVGKLSD VTRAVEGVAE HLDVQLSSFV
TVADVNKVKM YMKNFGEFYD DQISHASCII LSRTQNATEE KIAAAVAMLR EKNPTATIVT
TAWDALTGEQ ILKAMSTKDD FKTELIAMAA KANEEHAHED EEEEHEHHHH HDHDDDHDEH
CCCGHHHDHD DDDDEDEHEH HHHHDHDDDD HDEHCCCGHH HHHHGHDADE VFTSWGVETA
KKFSKADIEH ALTELDTGNY GMILRSKGIV DGGADGWLEF DYVPGEWEVR ARGADVGGKL
VVIGSKLDEK AIAALFGC
//
