ID D4KZ13_9FIRM Unreviewed; 314 AA.
AC D4KZ13;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Glycosyltransferases involved in cell wall biogenesis {ECO:0000313|EMBL:CBL12603.1};
GN ORFNames=RO1_20710 {ECO:0000313|EMBL:CBL12603.1};
OS Roseburia intestinalis XB6B4.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Roseburia.
OX NCBI_TaxID=718255 {ECO:0000313|EMBL:CBL12603.1, ECO:0000313|Proteomes:UP000008953};
RN [1] {ECO:0000313|EMBL:CBL12603.1, ECO:0000313|Proteomes:UP000008953}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=XB6B4 {ECO:0000313|EMBL:CBL12603.1,
RC ECO:0000313|Proteomes:UP000008953};
RG metaHIT consortium -- http://www.metahit.eu/;
RA Pajon A., Turner K., Parkhill J., Bernalier A.;
RT "The genome sequence of Roseburia intestinalis XB6B4.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBL12603.1, ECO:0000313|Proteomes:UP000008953}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=XB6B4 {ECO:0000313|EMBL:CBL12603.1,
RC ECO:0000313|Proteomes:UP000008953};
RA Pajon A.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 2 family. GtrB
CC subfamily. {ECO:0000256|ARBA:ARBA00038152}.
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DR EMBL; FP929050; CBL12603.1; -; Genomic_DNA.
DR RefSeq; WP_006855913.1; NC_021012.1.
DR AlphaFoldDB; D4KZ13; -.
DR CAZy; GT2; Glycosyltransferase Family 2.
DR GeneID; 61434479; -.
DR KEGG; rix:RO1_20710; -.
DR PATRIC; fig|718255.3.peg.3240; -.
DR HOGENOM; CLU_033536_0_1_9; -.
DR Proteomes; UP000008953; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR CDD; cd04187; DPM1_like_bac; 1.
DR InterPro; IPR001173; Glyco_trans_2-like.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR48090:SF8; PROPHAGE BACTOPRENOL GLUCOSYL TRANSFERASE HOMOLOG; 1.
DR PANTHER; PTHR48090; UNDECAPRENYL-PHOSPHATE 4-DEOXY-4-FORMAMIDO-L-ARABINOSE TRANSFERASE-RELATED; 1.
DR Pfam; PF00535; Glycos_transf_2; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transferase {ECO:0000313|EMBL:CBL12603.1};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 229..250
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 4..167
FT /note="Glycosyltransferase 2-like"
FT /evidence="ECO:0000259|Pfam:PF00535"
SQ SEQUENCE 314 AA; 36126 MW; 96BA6DA41C3A2B09 CRC64;
MKISLIVPCY NEQEALPIFY RETKKVMESM DCDYEMIFVN DGSKDGTLEL LKEFAKEDTH
VTYIGFSRNF GKEAAMYAGF CNVTGDYAAV MDADMQDPPS LLPQMLDILE NQGYDSVATR
RATRKGEPVI RSWFARMFYR LINKISDADI VDGARDFRLM KRSMVDAIVE MGEYNRFSKG
IFGWIGFKTY WLPYENVNRV AGETKWSFWK LFRYAIDGVI NFSQAPLSVA SWFGMFMTFV
SFIAVVFIII RKLIFGDPVD GWASTVCIIT LIGGIQLFCM GIMGQYIAKT YLEVKKRPHY
IVSDTNREDM EKVK
//
