ID D4LW73_9FIRM Unreviewed; 667 AA.
AC D4LW73;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 59.
DE SubName: Full=Diguanylate cyclase (GGDEF) domain {ECO:0000313|EMBL:CBL21876.1};
GN ORFNames=CK5_02480 {ECO:0000313|EMBL:CBL21876.1};
OS Blautia obeum A2-162.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae; Blautia.
OX NCBI_TaxID=657314 {ECO:0000313|EMBL:CBL21876.1, ECO:0000313|Proteomes:UP000008955};
RN [1] {ECO:0000313|EMBL:CBL21876.1, ECO:0000313|Proteomes:UP000008955}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A2-162 {ECO:0000313|EMBL:CBL21876.1,
RC ECO:0000313|Proteomes:UP000008955};
RG metaHIT consortium -- http://www.metahit.eu/;
RA Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT "The genome sequence of Ruminococcus obeum A2-162.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBL21876.1, ECO:0000313|Proteomes:UP000008955}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A2-162 {ECO:0000313|EMBL:CBL21876.1,
RC ECO:0000313|Proteomes:UP000008955};
RA Pajon A.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FP929054; CBL21876.1; -; Genomic_DNA.
DR AlphaFoldDB; D4LW73; -.
DR KEGG; rob:CK5_02480; -.
DR PATRIC; fig|657314.3.peg.959; -.
DR HOGENOM; CLU_020864_1_0_9; -.
DR Proteomes; UP000008955; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR028082; Peripla_BP_I.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR30146:SF152; HTH-TYPE TRANSCRIPTIONAL REGULATOR EBGR-RELATED; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 536..667
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 667 AA; 76579 MW; C9F956284282A7E9 CRC64;
MKEHRRYNIG ILIGGVHTYF PKEHILGIAE AAEELDANVC FFLGTQTKDF FEDMLGGTHK
NSFDYQFNTI HDYSLIGGLD GLIINYGTLG LQLKNESAER FALKFNSIPT VFLTEIVHEP
NCHSLICDNK QGIRLVMAHL IEKHHCSNIL FVSGPAQNTD AKERKAAYFE MMERYHLPVS
DKMIAQGDYS EFVDRQVNQL LDDNPNAEAI VFANDEMAFA GYRVCEKRGL KVGKDILITG
FDDCERASGM DPALTTVVQD GVLMGRMAVY DLIYKLDGKD ALSRRVPVSL CIRESCGCQE
KNGKTPNTPL NFVDQIHKLN RTITNMKLEL INFQRKSWFI PSLARNLNDC MDDEHAFLLE
AMENMRELRT KCTYLFLLDE PVVYRKDDKW KCPENLRLAA YYKKEEVDAF HLYDRLPVSK
EGGICQLMED GERHQFMIFL LFSGERQYGL LACDIQQEEF PFFYVISLQI GLSLRYLEIS
KAEAARRREM TKDLEMIRER NRILGIMSAN DELTGLLNLR GFTEEAKKFC HEEQGQRTYL
ICGDLDHLKE INDNWGHPAG NFALRSVAEI LRGCIRSDDV LARVGGDEFL ILLKCTEKGY
QETFRKRVKD ACTYFNQKSD KPFLVEISLG IAEFCSGPQT DIQQVIATAD QFLYEAKKHR
RKSIRRP
//
