ID D4M0A4_9FIRM Unreviewed; 2439 AA.
AC D4M0A4;
DT 18-MAY-2010, integrated into UniProtKB/TrEMBL.
DT 18-MAY-2010, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=DNA methylase {ECO:0000313|EMBL:CBL27464.1};
GN ORFNames=RTO_30660 {ECO:0000313|EMBL:CBL27464.1};
OS [Ruminococcus] torques L2-14.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Mediterraneibacter.
OX NCBI_TaxID=657313 {ECO:0000313|EMBL:CBL27464.1, ECO:0000313|Proteomes:UP000008956};
RN [1] {ECO:0000313|EMBL:CBL27464.1, ECO:0000313|Proteomes:UP000008956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L2-14 {ECO:0000313|EMBL:CBL27464.1,
RC ECO:0000313|Proteomes:UP000008956};
RG metaHIT consortium -- http://www.metahit.eu/;
RA Pajon A., Turner K., Parkhill J., Duncan S., Flint H.;
RT "The genome sequence of Ruminococcus torques L2-14.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CBL27464.1, ECO:0000313|Proteomes:UP000008956}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L2-14 {ECO:0000313|EMBL:CBL27464.1,
RC ECO:0000313|Proteomes:UP000008956};
RA Pajon A.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FP929055; CBL27464.1; -; Genomic_DNA.
DR KEGG; rto:RTO_30660; -.
DR PATRIC; fig|657313.3.peg.2948; -.
DR HOGENOM; CLU_000181_0_1_9; -.
DR Proteomes; UP000008956; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR GO; GO:0008170; F:N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0006306; P:DNA methylation; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR003356; DNA_methylase_A-5.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR41313; ADENINE-SPECIFIC METHYLTRANSFERASE; 1.
DR PANTHER; PTHR41313:SF1; DNA METHYLASE ADENINE-SPECIFIC DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF02384; N6_Mtase; 1.
DR Pfam; PF04851; ResIII; 1.
DR PRINTS; PR00507; N12N6MTFRASE.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Methyltransferase {ECO:0000313|EMBL:CBL27464.1};
KW Transferase {ECO:0000313|EMBL:CBL27464.1}.
FT DOMAIN 2015..2187
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 266..390
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 665..700
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2414..2439
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1735..1785
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2357..2384
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 266..288
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 289..303
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 335..350
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..371
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..387
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2439 AA; 278102 MW; 359FD5259955DCDA CRC64;
MARKYDLISE LYNRTCKTVV SNPQNWQAFL ASACRNYKLR YDEQLLVYAQ RPDATAVLEI
EQWNKIFGRW VNRGARGIAV FADENRSRQR LTHYFDISDT HESRYSRTVP IWDMRQEYEA
DVIETLESTF GEIENKSSLA EAIMGAARNA AEDNIPDYLQ DLYYATEGSS FEEVEEDIVA
FIYKNVVTNS VAYMMMSRLG VDTDGYFELD DFRDVTNFNT QETLNALGFA TSDIAEMGLT
EISKTITALN RQNRIIVGQD RNEYNKVENN DERSLDNERT DLHDGGRLQP SESETSTAAG
SDVGQIRSDE ERVSEGTSQS PLLQSPDEGR TDTALGGSGT ESQQDGGNNP EADGTERGSD
RTDESGGYDE MGSSDERSSQ LGTGNRESGS DIRLEYYDRT HEDKSLPFFG RDEVINEILR
TTPHLSASLE EIKDYYERNL DNKDRTEYIK SIFNNDYTEL TLEDGRTVGY KTFENVLHLW
EGKYDSRTAQ SFYDWAVIAR HFEAMRLLGE LSDSIKPLPS MDGQMTFILD GQAEEKKPSA
FTFSQEIIDA VLTNGSGFSE GKMRIYEQFE KSLSAKENAD FLKNEYGWGG SYPVIIGAGI
DESHDGKGIT ITKGIGKENP HITLSWSQVE KRIGELIRMD RYLNPKEKEH YPRWLESQEE
RRTKIAETKR NREILSNAPP EQEVEPTEKE PEEAEQPQDV QYEYHLGDKV YIGASEYEIL
SVDDERVMLY DYDMLLFNKE FSRTEFDRKV RENPMNEHLI VKEEPAEERN EAEEVQTNMG
SMPIEDYREI VASQSGFDSY DEMHRQGYRI GNGYDKEPEP VVPAWEQKKK VKGFDLHPDV
PMADRHTFNL RENEVETVGK KERFRRNIMA IQLLKKCQEE NRFATPEEQI ILSKYVGWGG
LSEAFDENNS AWATEYLELS SVLTPEEYAS ARESTLTAFY TPPEVITTIY KAMEQMGFKE
GNLLEPSCGI GNFIGMLPDS MQDSKIYGVE LDTISAGIAQ QLYQKTTIAA QGFEETNLPD
SFFDGVVGNV PFGDFKVSDK RYDKHKFLIH DYFFAKSLDK LRPGGVMAFV TSKGTMDKET
LAVRKYIAQR AELLGAIRLP NNTFKGNAGT EVVSDILILQ KRDRLIDIEP DWVHLDTDEN
GIKMNSYFVQ HPEMILGEMK MVSGRFGMEA TCVPYENADL AAQLDEAVAN IHGEITEYET
EEELEEEDNS IPADPTVRNF SYTVVGDKIY YRENSRMTPV EVSATAENRI KGMIAIRNSV
RTLIELQTED YPDSEIKAEQ ERLNRLYDTF SGKYGLINSR ANTSAFSQDS SFSLLSALEI
IGEDGELERK ADMFSKRTIK PHTPVTSVDT ASEALAVSLG EKATIDMDYM MELSGKSENE
IFEDLKGVIF LNPLYEYGNS YEPKYLMADE YLSGNVREKL RIAKNSAELY PEDYKVNVEA
LQKVQPKDLT ASEISVRLGA TWLPPDDVQE FIFHLLETPR YAQWNIKVHF SPFTSEWNIE
GKSYDKGNVR AYNTYGTSRI NAYKIIEETL NLKDVRIFDY IEDDEGKKKA VLNKKETAIA
QSKQEMIKQE FQDWIWSDPE RRERLCKSYN EKFNSVRPRE YDGSHIIFNG MNPEIELREH
QKNAVAHILY GGNTLLAHAV GAGKTFEMVA AAQESKRLGL CNKSLFVVPN HLTEQWAAEY
LQLYPAANIL VATKKDFETK NRKKFCGRIA TGDYDAVIIG HSQFEKIPMS IERQRAILEQ
QLEEITEGIA ELKRNRGENF SVKQLEKSKK SIKQKLDKLN DQTKKDDVVT FEELGVDRLF
VDESHYYKNL YLYTKMRNVG GIAQTEAQKS SDLFMKCRYL DEITGGRGTV FATGTPISNS
MVELYTIQRY LQYNTLVKNG LQHFDAWAST FGETITAVEL TPEGTGYRAK TRFAKFYNLP
ELMAMFKEVA DIKTADMLNL PVPEAKYHNI AVKPSEMQKE MVASLAERAE QVRGGGVDSS
VDNMLKITND GRKLALDQRM LNDMLPDFEG SKINACVDNI YRIWEKNTDK KSAQLVFCDL
STPKNDGTFS VYNDIRKKLI ERGIPESEVK FIHEADTDMK KKELFQKTRK GEVRVLLGST
QKMGAGTNVQ DKLIALHDVD CPWRPSDLEQ RSGRIVRQGN ENPQVDIYRY VTEQTFDAYL
YQLVEGKQKF ASQIMTSKSP VRSAEDIDET ALSYAEIKML ATGNPYIKEK MDLDIQVQKL
KMLKSNFLSE KYGLEDKVIK FYPQQIAYLK SRVEGLTKDV ETAKLHPKPI DEQPLGMMVS
GVSYSEKSEA GQAIINTCKS MNSPDAIPLG EYRGFQMELY FDTVQRNYVV KLKGETSRDV
PLGDDSHGNI VRIDNGIERF EEALADTKNS LENTEKQFET AKQEIEKPFA KEEELKAKTA
RLDELNILLN MDKKENEIVG GEPDEGEAVG GRKEKSYER
//
