ID   D4YK52_9MICO            Unreviewed;       279 AA.
AC   D4YK52;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   SubName: Full=PHP domain protein {ECO:0000313|EMBL:EFG48344.1};
DE            EC=3.1.3.- {ECO:0000313|EMBL:EFG48344.1};
GN   ORFNames=HMPREF0183_0312 {ECO:0000313|EMBL:EFG48344.1};
OS   Brevibacterium mcbrellneri ATCC 49030.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Brevibacteriaceae;
OC   Brevibacterium.
OX   NCBI_TaxID=585530 {ECO:0000313|EMBL:EFG48344.1, ECO:0000313|Proteomes:UP000005714};
RN   [1] {ECO:0000313|EMBL:EFG48344.1, ECO:0000313|Proteomes:UP000005714}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49030 {ECO:0000313|EMBL:EFG48344.1,
RC   ECO:0000313|Proteomes:UP000005714};
RA   Qin X., Bachman B., Battles P., Bell A., Bess C., Bickham C., Chaboub L.,
RA   Chen D., Coyle M., Deiros D.R., Dinh H., Forbes L., Fowler G.,
RA   Francisco L., Fu Q., Gubbala S., Hale W., Han Y., Hemphill L.,
RA   Highlander S.K., Hirani K., Hogues M., Jackson L., Jakkamsetti A.,
RA   Javaid M., Jiang H., Korchina V., Kovar C., Lara F., Lee S., Mata R.,
RA   Mathew T., Moen C., Morales K., Munidasa M., Nazareth L., Ngo R.,
RA   Nguyen L., Okwuonu G., Ongeri F., Patil S., Petrosino J., Pham C., Pham P.,
RA   Pu L.-L., Puazo M., Raj R., Reid J., Rouhana J., Saada N., Shang Y.,
RA   Simmons D., Thornton R., Warren J., Weissenberger G., Zhang J., Zhang L.,
RA   Zhou C., Zhu D., Muzny D., Worley K., Gibbs R.;
RL   Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EFG48344.1}.
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DR   EMBL; ADNU01000012; EFG48344.1; -; Genomic_DNA.
DR   RefSeq; WP_005882053.1; NZ_ADNU01000012.1.
DR   AlphaFoldDB; D4YK52; -.
DR   STRING; 585530.HMPREF0183_0312; -.
DR   eggNOG; COG0613; Bacteria.
DR   OrthoDB; 9804333at2; -.
DR   Proteomes; UP000005714; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   CDD; cd07438; PHP_HisPPase_AMP; 1.
DR   Gene3D; 1.10.150.650; -; 1.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR004013; PHP_dom.
DR   InterPro; IPR003141; Pol/His_phosphatase_N.
DR   InterPro; IPR016195; Pol/histidinol_Pase-like.
DR   PANTHER; PTHR42924; EXONUCLEASE; 1.
DR   PANTHER; PTHR42924:SF3; POLIIIAC DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF02811; PHP; 1.
DR   SMART; SM00481; POLIIIAc; 1.
DR   SUPFAM; SSF89550; PHP domain-like; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:EFG48344.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000005714}.
FT   DOMAIN          2..67
FT                   /note="Polymerase/histidinol phosphatase N-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00481"
SQ   SEQUENCE   279 AA;  30267 MW;  3F17B42AF6BB6ADA CRC64;
     MIDLHTHSAF SDGTQTPEEL LAQASDAGVT TLGLTDHDTV AGWSPAVQAA RTHGVQLVRG
     MEVSCRFQGV SVHMLSYLHN PDGARLTAQT EEIRKARVTR TRKIVDLLSA DFPITWEHVC
     EHVGEGATVG RPHIADALVH QGITRDRSEA FATLLHRDSP YYVSMPVISP IEAIDMIHDA
     GGVAVFAHPA ASSRGQVVTD AGMRTIIEAG LDGLEIDHRD NPLAERQKLR ERAQEYGLIV
     TGSSDYHGAG KPNTLAENTT SPHMCERILE RAHGVDLVV
//