ID D5C172_NITHN Unreviewed; 644 AA.
AC D5C172;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Aconitate hydratase {ECO:0000313|EMBL:ADE14629.1};
GN OrderedLocusNames=Nhal_1482 {ECO:0000313|EMBL:ADE14629.1};
OS Nitrosococcus halophilus (strain Nc4).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC Nitrosococcus.
OX NCBI_TaxID=472759 {ECO:0000313|EMBL:ADE14629.1, ECO:0000313|Proteomes:UP000001844};
RN [1] {ECO:0000313|Proteomes:UP000001844}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nc4 {ECO:0000313|Proteomes:UP000001844};
RG US DOE Joint Genome Institute;
RA Campbell M.A., Malfatti S.A., Chain P.S.G., Heidelberg J.F., Ward B.B.,
RA Klotz M.G.;
RT "Complete genome sequence of Nitrosococcus halophilus Nc4, a salt-adapted,
RT aerobic obligate ammonia-oxidizing sulfur purple bacterium.";
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001798; ADE14629.1; -; Genomic_DNA.
DR RefSeq; WP_013032520.1; NC_013960.1.
DR AlphaFoldDB; D5C172; -.
DR STRING; 472759.Nhal_1482; -.
DR KEGG; nhl:Nhal_1482; -.
DR eggNOG; COG1048; Bacteria.
DR HOGENOM; CLU_006714_2_3_6; -.
DR OrthoDB; 9764318at2; -.
DR Proteomes; UP000001844; Chromosome.
DR GO; GO:0003994; F:aconitate hydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.30.499.10; Aconitase, domain 3; 2.
DR Gene3D; 3.20.19.10; Aconitase, domain 4; 1.
DR InterPro; IPR015931; Acnase/IPM_dHydase_lsu_aba_1/3.
DR InterPro; IPR001030; Acoase/IPM_deHydtase_lsu_aba.
DR InterPro; IPR015928; Aconitase/3IPM_dehydase_swvl.
DR InterPro; IPR036008; Aconitase_4Fe-4S_dom.
DR InterPro; IPR006250; Aconitase_put.
DR InterPro; IPR000573; AconitaseA/IPMdHydase_ssu_swvl.
DR NCBIfam; TIGR01342; acon_putative; 1.
DR PANTHER; PTHR43160; ACONITATE HYDRATASE B; 1.
DR PANTHER; PTHR43160:SF3; ACONITATE HYDRATASE, MITOCHONDRIAL; 1.
DR Pfam; PF00330; Aconitase; 2.
DR Pfam; PF00694; Aconitase_C; 1.
DR PRINTS; PR00415; ACONITASE.
DR SUPFAM; SSF53732; Aconitase iron-sulfur domain; 1.
DR SUPFAM; SSF52016; LeuD/IlvD-like; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001844}.
FT DOMAIN 8..284
FT /note="Aconitase/3-isopropylmalate dehydratase large
FT subunit alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF00330"
FT DOMAIN 286..407
FT /note="Aconitase/3-isopropylmalate dehydratase large
FT subunit alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF00330"
FT DOMAIN 511..577
FT /note="Aconitase A/isopropylmalate dehydratase small
FT subunit swivel"
FT /evidence="ECO:0000259|Pfam:PF00694"
SQ SEQUENCE 644 AA; 70970 MW; 011A9FE08BA8F7EB CRC64;
MVQNVTQKLI ANHLISGEME PGAEIALRID QTLTQDATGT LVMLEFEAMG IPRVKTELSV
QYVDHNLIQE DFKNPDDHLF LRSACKKFGL WYSRPGNGVS HPVHMERFGV PGKTLLGSDS
HTPAAGSLGM LAIGAGGLEV AMAMAGEPFY MKMPKVWGVK LTGRLPDWVS AKDVILEMLR
RHDVDGGRGK IIEYYGPGLA NLTAMDRHVI ANMGAELGAT TTVFPADGAV KEFLKTQGRE
EAWAELVAEP NADYDEHEEI NLSELEPLIA LPSSPGKVVP VREVAGREIY QTYIGSSANP
GLRDFAIAAL IVDGKQVHDR VSFDINPTSR QILENLISLE LLGKLIHAGA RLHQAGCNGC
IGMGQAPATG RISLRTVPRN FPGRSGTKED QVYLCSPETA AASALTGEIT DPRTLAMDYP
PFREPKSIRI NISMLSPPAE KEEEVELEKG PNIQPLPPFE PLPDDLEGPV LLKVGDDIST
DEIMPAGARV LPFRSNIPEI SKFVFEPIDE NYYQRAMEHQ QQGSWVVGGE NYGQGSSREH
AALAPRYLGL KAVLAKSFAR IHWQNLVNFG ILPLTFVKPD DWERIDQSDV LYLANVRNAI
QRGEKLTVSN KTKQEDYELR HSMSPRQVEM ILEGSLINLI RKKQ
//
