ID D5C1Y3_NITHN Unreviewed; 763 AA.
AC D5C1Y3;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=CHASE2 domain protein {ECO:0000313|EMBL:ADE16571.1};
GN OrderedLocusNames=Nhal_3548 {ECO:0000313|EMBL:ADE16571.1};
OS Nitrosococcus halophilus (strain Nc4).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC Nitrosococcus.
OX NCBI_TaxID=472759 {ECO:0000313|EMBL:ADE16571.1, ECO:0000313|Proteomes:UP000001844};
RN [1] {ECO:0000313|Proteomes:UP000001844}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nc4 {ECO:0000313|Proteomes:UP000001844};
RG US DOE Joint Genome Institute;
RA Campbell M.A., Malfatti S.A., Chain P.S.G., Heidelberg J.F., Ward B.B.,
RA Klotz M.G.;
RT "Complete genome sequence of Nitrosococcus halophilus Nc4, a salt-adapted,
RT aerobic obligate ammonia-oxidizing sulfur purple bacterium.";
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001798; ADE16571.1; -; Genomic_DNA.
DR AlphaFoldDB; D5C1Y3; -.
DR STRING; 472759.Nhal_3548; -.
DR KEGG; nhl:Nhal_3548; -.
DR eggNOG; COG2114; Bacteria.
DR eggNOG; COG4252; Bacteria.
DR HOGENOM; CLU_000445_85_1_6; -.
DR OrthoDB; 9806704at2; -.
DR Proteomes; UP000001844; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR007890; CHASE2.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR PANTHER; PTHR43081:SF1; PH-SENSITIVE ADENYLATE CYCLASE RV1264; 1.
DR Pfam; PF05226; CHASE2; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM01080; CHASE2; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001844};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 377..397
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..448
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 484..613
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 763 AA; 85486 MW; 2806C5E01A707A72 CRC64;
MSRPAKAAVL GLLTAWGGFL ATIAPSLGRL ELDLGLLWLF KLRGPRAAPE EVVIVTIDRE
SSDWFGLPNE PDKWPRKLHA RLVHRLTQSG AAVIAFDVIF DEPRNPDQDQ LFAEAIREAG
NVVLFEYLKK KRKRVAIGGK QAEIEIEERL PPVSELASAA AMTAPFPLPK VPVRVNQAWL
FKLGIPTLPV TALQVYARPY YEDFLRLLNE VEMATGETQR LKSEWETAPG QSDLTALAIH
LQKLFQGEAQ LPQSLLARLQ SSESLTHSQG HSVVAALIRV FSSPESLFLD FYGPPHSIST
IPYHRILAGE GEASLPVSFK GKAVFVGFSE QFQPEQKDGF YTVYSQPDGL DISGVEIAAT
VFANLLESRS VTPLPLFLHY LVIVLWGVAI GFLFLFLNAY ALIPTAVALA VGYMSVAYHL
FVSEGLWLPL VIPLLWQLPF GLLGALLWRY LTIGKAIRPY LPDWFWRRWN RHSEPPPAQI
AKGVCLATDV QQYTPLAERL ELNQLYLLLN EYFQNIFEPV KFRGGEISDI RGDAIMAIWV
EAVRKQSLRE QACLAALDIV DAVAEFNHRT PEVSLPTRIG LHYGKMVIGE VGSRDHLEYR
SVGDVANVAS RIENLNKILG TCVLTSGEVI AGLESIFTRK VGCFRVRGRS QPLAIHELVC
RTEEVNKTLR DHCEQFEAAL RIFQRQRWQE ALLAFRALLA SYGNDGPSYF YLRLAGHYAQ
KPPATSWDGI IDLGYVEERR KATRSGLTVT AEHREKSWKK TSM
//
