ID D5C2E2_NITHN Unreviewed; 508 AA.
AC D5C2E2;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Efflux transporter, RND family, MFP subunit {ECO:0000313|EMBL:ADE14801.1};
GN OrderedLocusNames=Nhal_1673 {ECO:0000313|EMBL:ADE14801.1};
OS Nitrosococcus halophilus (strain Nc4).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Chromatiales; Chromatiaceae;
OC Nitrosococcus.
OX NCBI_TaxID=472759 {ECO:0000313|EMBL:ADE14801.1, ECO:0000313|Proteomes:UP000001844};
RN [1] {ECO:0000313|Proteomes:UP000001844}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Nc4 {ECO:0000313|Proteomes:UP000001844};
RG US DOE Joint Genome Institute;
RA Campbell M.A., Malfatti S.A., Chain P.S.G., Heidelberg J.F., Ward B.B.,
RA Klotz M.G.;
RT "Complete genome sequence of Nitrosococcus halophilus Nc4, a salt-adapted,
RT aerobic obligate ammonia-oxidizing sulfur purple bacterium.";
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC family. {ECO:0000256|ARBA:ARBA00009477}.
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DR EMBL; CP001798; ADE14801.1; -; Genomic_DNA.
DR RefSeq; WP_013032688.1; NC_013960.1.
DR AlphaFoldDB; D5C2E2; -.
DR STRING; 472759.Nhal_1673; -.
DR KEGG; nhl:Nhal_1673; -.
DR eggNOG; COG0845; Bacteria.
DR HOGENOM; CLU_018816_13_4_6; -.
DR OrthoDB; 9806939at2; -.
DR Proteomes; UP000001844; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 2.40.30.170; -; 1.
DR Gene3D; 2.40.420.20; -; 1.
DR Gene3D; 6.10.140.730; -; 1.
DR InterPro; IPR032317; HlyD_D23.
DR InterPro; IPR006143; RND_pump_MFP.
DR InterPro; IPR032693; YtkA-like_dom.
DR NCBIfam; TIGR01730; RND_mfp; 1.
DR PANTHER; PTHR30097; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR PANTHER; PTHR30097:SF15; CATION EFFLUX SYSTEM PROTEIN CUSB; 1.
DR Pfam; PF16576; HlyD_D23; 1.
DR Pfam; PF13115; YtkA; 1.
DR SUPFAM; SSF111369; HlyD-like secretion proteins; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000001844}.
FT DOMAIN 66..140
FT /note="YtkA-like"
FT /evidence="ECO:0000259|Pfam:PF13115"
FT DOMAIN 210..423
FT /note="RND efflux pump membrane fusion protein barrel-
FT sandwich"
FT /evidence="ECO:0000259|Pfam:PF16576"
FT REGION 28..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 508 AA; 55041 MW; 399D4E22F0A49EF6 CRC64;
MTRFILLFIA GAALLALGIV IGWQLPPSPP PDATPPERTG SDVPIRSRGI GQPTYRSGPF
RVGVAVEPAA PQVGENRLKV VLEDRKGNPV SGAQIRAVAE MPAMGAMPAM QAPAEMQEIE
PGLYQGTFDL PMEGSWPLTL AISASGMADR QISFDMATGR AGLQLTSGAT RIDGSGEATL
EEAPPGTVTL DARRRQLIGV ETAEAKLVEM VRTIRAVGRV IYDETRLTDV SLKFDAWIGK
LYVNYLGAKV QKGQPLFTVY GPELLAAQQE YLEIKRRAGR SDVTQALLEA ARKRLSLWDM
TPGEIAALER RDVPYDYVPI HAPRSGTVVA KNVVEGTAQQ AGATLLRIAD LSRVWVEAEV
YEAELPLVGE GMKAEIHLPY LPDQRFQGVV DYVYPYLEGQ SRTGRIRITL ANPNGVLKPD
MYAEVKLKAE LGQRLTVPEE AVIIAGETRV VFEDLGGGRL APRLVQTGQQ ANGLMEILSG
LESGDRVVTS GNFLIAAESR LKAGIQQW
//
