ID D5CS89_SIDLE Unreviewed; 515 AA.
AC D5CS89;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=PAS/PAC sensor signal transduction histidine kinase {ECO:0000313|EMBL:ADE11825.1};
GN OrderedLocusNames=Slit_1592 {ECO:0000313|EMBL:ADE11825.1};
OS Sideroxydans lithotrophicus (strain ES-1).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Gallionellaceae; Sideroxydans.
OX NCBI_TaxID=580332 {ECO:0000313|EMBL:ADE11825.1, ECO:0000313|Proteomes:UP000001625};
RN [1] {ECO:0000313|EMBL:ADE11825.1, ECO:0000313|Proteomes:UP000001625}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ES-1 {ECO:0000313|EMBL:ADE11825.1,
RC ECO:0000313|Proteomes:UP000001625};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Munk A.C., Detter J.C., Han C., Tapia R., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Ivanova N., Emerson D., Woyke T.;
RT "Complete sequence of Sideroxydans lithotrophicus ES-1.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP001965; ADE11825.1; -; Genomic_DNA.
DR RefSeq; WP_013029723.1; NC_013959.1.
DR AlphaFoldDB; D5CS89; -.
DR STRING; 580332.Slit_1592; -.
DR KEGG; slt:Slit_1592; -.
DR eggNOG; COG4585; Bacteria.
DR HOGENOM; CLU_528815_0_0_4; -.
DR OrthoDB; 9813412at2; -.
DR Proteomes; UP000001625; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR CDD; cd00130; PAS; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF13188; PAS_8; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:ADE11825.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001625};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 237..289
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 419..505
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 515 AA; 56904 MW; 23425987B3AF5676 CRC64;
MPTVVVVIAA LALFAGAYLV LVSSFGFFRP APVRASQHYQ DLFHNSVAGI FVINADAFAQ
FTIEEMNEAA TGFISTACQG RLISELVQNL PNEKSTFFVR LIDALNSVVT NDCDLEYGTA
CWHMTENRSI PLKVRLIPSA KIGNDRKIMG FLQNAGEIEE TRDLLTARAN DFIALAEQSP
DTIARYDLKG HCIYANRAFN KLAAASSQTQ PFLPVHDYYG MNHLQRILGV LDSGMDDEME
CTWLTATGET VTSHIRLIPE HGATGEVIGV LSIGRDISTL KETERHLRDS RALLRDLTAR
REIEEGLVRK EMARKMHEEY GQLLSALRMK LAMLSMRYGK DSAILKVQID DALVLLDGTI
SHMRDIVSSM YPSVLNTGIS SALEWLADDC LAGTGMHYEV HVDEGITGIS EGFTGIVFKI
VQIALSNVLL HAEANAVAIT FEERNKGYRL EVRDDGKGFD LDRSRRNSLG MVAMEELSNM
LSGEIVFLSE PGKGTVVEVC FPLVDATQPV MFEAL
//
