ID D5CU13_SIDLE Unreviewed; 447 AA.
AC D5CU13;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Adenylate/guanylate cyclase {ECO:0000313|EMBL:ADE12325.1};
DE EC=4.6.1.2 {ECO:0000313|EMBL:ADE12325.1};
GN OrderedLocusNames=Slit_2097 {ECO:0000313|EMBL:ADE12325.1};
OS Sideroxydans lithotrophicus (strain ES-1).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Gallionellaceae; Sideroxydans.
OX NCBI_TaxID=580332 {ECO:0000313|EMBL:ADE12325.1, ECO:0000313|Proteomes:UP000001625};
RN [1] {ECO:0000313|EMBL:ADE12325.1, ECO:0000313|Proteomes:UP000001625}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ES-1 {ECO:0000313|EMBL:ADE12325.1,
RC ECO:0000313|Proteomes:UP000001625};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Munk A.C., Detter J.C., Han C., Tapia R., Larimer F., Land M.,
RA Hauser L., Kyrpides N., Ivanova N., Emerson D., Woyke T.;
RT "Complete sequence of Sideroxydans lithotrophicus ES-1.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001965; ADE12325.1; -; Genomic_DNA.
DR AlphaFoldDB; D5CU13; -.
DR STRING; 580332.Slit_2097; -.
DR KEGG; slt:Slit_2097; -.
DR eggNOG; COG2114; Bacteria.
DR HOGENOM; CLU_001072_14_1_4; -.
DR Proteomes; UP000001625; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR GO; GO:0004383; F:guanylate cyclase activity; IEA:UniProtKB-EC.
DR GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR CDD; cd07302; CHD; 1.
DR Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR InterPro; IPR001054; A/G_cyclase.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR PANTHER; PTHR11920:SF335; GUANYLATE CYCLASE 32E; 1.
DR PANTHER; PTHR11920; GUANYLYL CYCLASE; 1.
DR Pfam; PF00211; Guanylate_cyc; 1.
DR SMART; SM00044; CYCc; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:ADE12325.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000001625};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 34..56
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 62..80
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 87..107
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 113..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 248..375
FT /note="Guanylate cyclase"
FT /evidence="ECO:0000259|PROSITE:PS50125"
SQ SEQUENCE 447 AA; 49378 MW; 4545E3CA50F93EBA CRC64;
MAAGGMGGMV QHIDSKEVKP EVMDTQEEKL RKSLLIFAAA FMTFAVMLWL AIYWMMGLNF
SSNVPLGYQA VSVASLIYYM RTRNFEVLRF VQLTLFLFAP FIMQWSIGSS VTSSGVALWA
LLAPIGALVV SGWKESIPWF FAYIVLTAVS GFFDFYLGSG TATGIPMNTI GVFFALNFAA
MSSILYFLVR YFVVETEKIK IQLDQQHALL AEEQKKSERV LFNVLPSNIA ERLKNSQGLI
ADGYADVTVM FADLVNFTQL TEQMSPEQMV GLLNTVFSGF DELSEKYGLE KIKTIGDAYM
VVGGLSRERP DYVEDMANMA IDMLDFVARH PALVKRNLGI HIGIATGPVV AGVIGTKRFI
YDLWGDTVNI ASRLTDDARQ GHILTDKLTY NRLRFGYLFE PPNVLNVKGK GEMTSYRMIG
RVAHADGPDT AGNVYHLPAA GGAPASA
//
