ID D5E5K0_MYCCM Unreviewed; 332 AA.
AC D5E5K0;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Pyruvate dehydrogenase E1 component, beta subunit {ECO:0000313|EMBL:ADE19348.1};
DE EC=1.2.4.1 {ECO:0000313|EMBL:ADE19348.1};
GN Name=pdhB {ECO:0000313|EMBL:ADE19348.1};
GN OrderedLocusNames=MCRO_0411 {ECO:0000313|EMBL:ADE19348.1};
OS Mycoplasma crocodyli (strain ATCC 51981 / MP145).
OC Bacteria; Mycoplasmatota; Mollicutes; Mycoplasmataceae; Mycoplasma.
OX NCBI_TaxID=512564 {ECO:0000313|EMBL:ADE19348.1, ECO:0000313|Proteomes:UP000001845};
RN [1] {ECO:0000313|Proteomes:UP000001845}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51981 / MP145 {ECO:0000313|Proteomes:UP000001845};
RA Glass J.I., Durkin A.S., Hostetler J., Jackson J., Johnson J., May M.A.,
RA Paralanov V., Radune D., Szczypinski B., Brown D.R.;
RT "The complete genome of Mycoplasma crocodyli MP145.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MP145;
RA Ma Z., Wang X., Liu H.;
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ADE19348.1, ECO:0000313|Proteomes:UP000001845}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 51981 / MP145 {ECO:0000313|Proteomes:UP000001845};
RX PubMed=21460083; DOI=10.1128/JB.00309-11;
RA Brown D.R., Farmerie W.G., May M., Benders G.A., Durkin A.S., Hlavinka K.,
RA Hostetler J., Jackson J., Johnson J., Miller R.H., Paralanov V., Radune D.,
RA Szczypinski B., Glass J.I.;
RT "Genome sequences of Mycoplasma alligatoris A21JP2T and Mycoplasma
RT crocodyli MP145T.";
RL J. Bacteriol. 193:2892-2893(2011).
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
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DR EMBL; CP001991; ADE19348.1; -; Genomic_DNA.
DR RefSeq; WP_013054125.1; NC_014014.1.
DR AlphaFoldDB; D5E5K0; -.
DR STRING; 512564.MCRO_0411; -.
DR KEGG; mcd:MCRO_0411; -.
DR eggNOG; COG0022; Bacteria.
DR HOGENOM; CLU_012907_1_0_14; -.
DR OrthoDB; 8732661at2; -.
DR Proteomes; UP000001845; Chromosome.
DR GO; GO:0004739; F:pyruvate dehydrogenase (acetyl-transferring) activity; IEA:UniProtKB-EC.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:ADE19348.1};
KW Pyruvate {ECO:0000313|EMBL:ADE19348.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001845}.
FT DOMAIN 7..182
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 332 AA; 36490 MW; D29805811BA9C463 CRC64;
MSDKITVNNI QALNNAIDIA MEKDEKVVLF GEDAGFEGGV FRATEGLQAK YGKTRVFDTP
ISEAAIAGVA FGAAVAGLRP IGEIQFQGFS YPAMQQIFTQ AARIRNRSRG RYTAPMVIRM
PMGGGIRALE HHSEALEAIY SHVPGVKVVM PAFPYDTKGL FLSAITDPDP VIFLEPKKIY
RAGKQEIPAG HYTVEIGKAN VLIEGSDVTI VTYGAQVHEV LSAIRKLRAA NNNVSIELID
LRTLKPLDTN TIIESVKKTG RLLIAHEAVK SYSVSAEIMA RVNEKAFEYL KAPMMRVTGY
DITVPLAKGE HYQSVNDDKI IDKLNELMAF KY
//
