ID D5EA74_METMS Unreviewed; 197 AA.
AC D5EA74;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Indolepyruvate oxidoreductase subunit IorB {ECO:0000256|ARBA:ARBA00017709};
DE EC=1.2.7.8 {ECO:0000256|ARBA:ARBA00012812};
DE AltName: Full=Indolepyruvate ferredoxin oxidoreductase subunit beta {ECO:0000256|ARBA:ARBA00033011};
GN OrderedLocusNames=Mmah_0549 {ECO:0000313|EMBL:ADE36075.1};
OS Methanohalophilus mahii (strain ATCC 35705 / DSM 5219 / SLP).
OC Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC Methanosarcinales; Methanosarcinaceae; Methanohalophilus.
OX NCBI_TaxID=547558 {ECO:0000313|EMBL:ADE36075.1, ECO:0000313|Proteomes:UP000001059};
RN [1] {ECO:0000313|EMBL:ADE36075.1, ECO:0000313|Proteomes:UP000001059}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 35705 / DSM 5219 / SLP
RC {ECO:0000313|Proteomes:UP000001059};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA Lykidis A., Saunders E., Brettin T., Detter J.C., Han C., Land M.,
RA Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D.,
RA Spring S., Schneider S., Schroeder M., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Methanohalophilus mahii DSM 5219.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyzes the ferredoxin-dependent oxidative decarboxylation
CC of arylpyruvates. {ECO:0000256|ARBA:ARBA00002995}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=CoA + indole-3-pyruvate + 2 oxidized [2Fe-2S]-[ferredoxin] =
CC (indol-3-yl)acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-
CC [ferredoxin]; Xref=Rhea:RHEA:12645, Rhea:RHEA-COMP:10000, Rhea:RHEA-
CC COMP:10001, ChEBI:CHEBI:15378, ChEBI:CHEBI:16526, ChEBI:CHEBI:17640,
CC ChEBI:CHEBI:33737, ChEBI:CHEBI:33738, ChEBI:CHEBI:57271,
CC ChEBI:CHEBI:57287; EC=1.2.7.8;
CC Evidence={ECO:0000256|ARBA:ARBA00033657};
CC -!- SUBUNIT: Heterodimer of the IorA and IorB subunits.
CC {ECO:0000256|ARBA:ARBA00011238}.
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DR EMBL; CP001994; ADE36075.1; -; Genomic_DNA.
DR RefSeq; WP_013037018.1; NC_014002.1.
DR AlphaFoldDB; D5EA74; -.
DR STRING; 547558.Mmah_0549; -.
DR GeneID; 8982697; -.
DR KEGG; mmh:Mmah_0549; -.
DR HOGENOM; CLU_087284_1_1_2; -.
DR OrthoDB; 53326at2157; -.
DR Proteomes; UP000001059; Chromosome.
DR GO; GO:0043805; F:indolepyruvate ferredoxin oxidoreductase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR InterPro; IPR017719; Indolepyruvate_Fd_OxRdtase_bsu.
DR InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR NCBIfam; TIGR03334; IOR_beta; 1.
DR PANTHER; PTHR43854; INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORB; 1.
DR PANTHER; PTHR43854:SF1; INDOLEPYRUVATE OXIDOREDUCTASE SUBUNIT IORB; 1.
DR Pfam; PF01558; POR; 1.
DR SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:ADE36075.1}; Pyruvate {ECO:0000313|EMBL:ADE36075.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000001059}.
FT DOMAIN 16..193
FT /note="Pyruvate/ketoisovalerate oxidoreductase catalytic"
FT /evidence="ECO:0000259|Pfam:PF01558"
SQ SEQUENCE 197 AA; 21041 MW; C7FC58016483D07A CRC64;
MTSDLSYFDL VIAGVGGQGA VKVSDIIGKA AVSDEMSVRA AETHGMAQRG GSVVNYVRLG
CELGSLIPCG SAHGMLALEP VEAMRYIHDV SKDGIVVMNI SPIYPVTVTS GQCTYPDPKE
IAARIEKDYR VVAFDAVALA RQAGNIKTLN VVMLGAISSY LPIAEETLVE CIKNLVPPKT
IDTNLKAFRL GRETTRQ
//
