ID   D5EB40_METMS            Unreviewed;       840 AA.
AC   D5EB40;
DT   15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT   15-JUN-2010, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE            EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN   OrderedLocusNames=Mmah_0868 {ECO:0000313|EMBL:ADE36391.1};
OS   Methanohalophilus mahii (strain ATCC 35705 / DSM 5219 / SLP).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanohalophilus.
OX   NCBI_TaxID=547558 {ECO:0000313|EMBL:ADE36391.1, ECO:0000313|Proteomes:UP000001059};
RN   [1] {ECO:0000313|EMBL:ADE36391.1, ECO:0000313|Proteomes:UP000001059}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35705 / DSM 5219 / SLP
RC   {ECO:0000313|Proteomes:UP000001059};
RG   US DOE Joint Genome Institute (JGI-PGF);
RA   Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA   Lykidis A., Saunders E., Brettin T., Detter J.C., Han C., Land M.,
RA   Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D.,
RA   Spring S., Schneider S., Schroeder M., Klenk H.-P., Eisen J.A.;
RT   "The complete genome of Methanohalophilus mahii DSM 5219.";
RL   Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC         histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR   EMBL; CP001994; ADE36391.1; -; Genomic_DNA.
DR   RefSeq; WP_013037334.1; NC_014002.1.
DR   AlphaFoldDB; D5EB40; -.
DR   STRING; 547558.Mmah_0868; -.
DR   GeneID; 8983032; -.
DR   KEGG; mmh:Mmah_0868; -.
DR   HOGENOM; CLU_007294_0_0_2; -.
DR   OrthoDB; 3369at2157; -.
DR   Proteomes; UP000001059; Chromosome.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   CDD; cd00130; PAS; 4.
DR   Gene3D; 3.30.450.40; -; 2.
DR   Gene3D; 3.30.450.20; PAS domain; 4.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR001610; PAC.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR000700; PAS-assoc_C.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013655; PAS_fold_3.
DR   NCBIfam; TIGR00229; sensory_box; 4.
DR   PANTHER; PTHR43304:SF1; PAC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43304; PHYTOCHROME-LIKE PROTEIN CPH1; 1.
DR   Pfam; PF13185; GAF_2; 2.
DR   Pfam; PF08447; PAS_3; 3.
DR   Pfam; PF13426; PAS_9; 1.
DR   SMART; SM00065; GAF; 2.
DR   SMART; SM00086; PAC; 3.
DR   SMART; SM00091; PAS; 4.
DR   SUPFAM; SSF55781; GAF domain-like; 2.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 4.
DR   PROSITE; PS50113; PAC; 2.
DR   PROSITE; PS50112; PAS; 3.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000001059}.
FT   DOMAIN          1..74
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          169..206
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   DOMAIN          210..262
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          507..559
FT                   /note="PAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50113"
FT   DOMAIN          720..789
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
SQ   SEQUENCE   840 AA;  97099 MW;  A249F7B08CA3EB40 CRC64;
     MKSVLEDIVN ASPAIVFVWK EEERWPVEFV SKNISLFDYT PDDFISGALR YSDIIHPDDL
     EMVTEEVEKH LESGDEQFNL TYRVLTGKKD VRWVEERTII HHDPDNTYYE GIIMDITSRK
     MEEKKIIDGA MGMKKALETV INSSPVIVFL WRAEDDWPVE FVSENITQFG YEVEEFTSDN
     LVYGDIVHPD DIEKVRQGMA RCVAEGNRQF NKEYRILTKD GDVRWVDERT KIQHSDTGDV
     TYLQGIIVDI TERKNVENAL FLEEKRHEAL LKLYAMSDSS IQEIMDYARE QAVLLTESKI
     GFLAFLDETE TNYAVISWSN GKQSSDKAPA ESYSIWDEAL YHRTPIMNNE YLADKDTDQK
     LIQRNLSVPI FEGGRIAGIV GVANKGEDYT PTDVRQLKLL MQGMWNIIQQ KLADEELYQY
     MEELKRSSEI KSVLSDVIKN SPAVVFIWWA EEDWPVEFVS ENITQFGYTV HDFLSGKLVY
     ADIVHPYDLE RVQKELAKRI DAGHTDFNQE YRIMTKFGDV RWIDERTFIK YDEDGKVTYL
     QGIIVDITER KHANDFMHLQ YDLDSVLSSA TSNRETFNRL LDLALRITPI DSGALYLVDD
     KTGDLDLVAH HGLSEQFVNS TSHYERNSVQ TRLVMSGQAV YKHHSELSAI TSGKNLRYEG
     LHGTAIIPIR YHNEIIAALY LSSHSEYEIP DKSRHDLETI AKQIGEVLSN MHKEASVQKE
     INDLQILIDN VKEGIIVTDK KGALLYTNKI LEKWIRYSAD ELKKMDITDL YPLRYRHVLD
     SVEETLNQNR TYSEDIRLHS STGREIPCRV TFKNIKWNEK DCILGIYEHI NTSATSSHNT
//