ID D5ES75_PRER2 Unreviewed; 725 AA.
AC D5ES75;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 27-MAR-2024, entry version 64.
DE SubName: Full=Alpha-1,2-mannosidase family protein {ECO:0000313|EMBL:ADE81912.1};
GN OrderedLocusNames=PRU_1159 {ECO:0000313|EMBL:ADE81912.1};
OS Prevotella ruminicola (strain ATCC 19189 / JCM 8958 / 23).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Xylanibacter.
OX NCBI_TaxID=264731 {ECO:0000313|EMBL:ADE81912.1, ECO:0000313|Proteomes:UP000000927};
RN [1] {ECO:0000313|EMBL:ADE81912.1, ECO:0000313|Proteomes:UP000000927}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19189 / JCM 8958 / 23 {ECO:0000313|Proteomes:UP000000927};
RX PubMed=20585943; DOI=10.1007/s00248-010-9692-8;
RG North American Consortium for Rumen Bacteria;
RA Purushe J., Fouts D.E., Morrison M., White B.A., Mackie R.I.,
RA Coutinho P.M., Henrissat B., Nelson K.E.;
RT "Comparative genome analysis of Prevotella ruminicola and Prevotella
RT bryantii: insights into their environmental niche.";
RL Microb. Ecol. 60:721-729(2010).
CC -!- COFACTOR:
CC Name=Ca(2+); Xref=ChEBI:CHEBI:29108;
CC Evidence={ECO:0000256|ARBA:ARBA00001913};
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DR EMBL; CP002006; ADE81912.1; -; Genomic_DNA.
DR RefSeq; WP_013063899.1; NC_014033.1.
DR AlphaFoldDB; D5ES75; -.
DR STRING; 264731.PRU_1159; -.
DR CAZy; GH92; Glycoside Hydrolase Family 92.
DR KEGG; pru:PRU_1159; -.
DR eggNOG; COG3537; Bacteria.
DR HOGENOM; CLU_003690_2_2_10; -.
DR Proteomes; UP000000927; Chromosome.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.70.98.10; -; 1.
DR Gene3D; 1.20.1050.60; alpha-1,2-mannosidase; 1.
DR Gene3D; 1.20.1610.10; alpha-1,2-mannosidases domains; 1.
DR Gene3D; 3.30.2080.10; GH92 mannosidase domain; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR014718; GH-type_carb-bd.
DR InterPro; IPR005887; GH92_a_mannosidase_put.
DR InterPro; IPR041371; GH92_N.
DR InterPro; IPR012939; Glyco_hydro_92.
DR NCBIfam; TIGR01180; aman2_put; 1.
DR PANTHER; PTHR12143; PEPTIDE N-GLYCANASE PNGASE -RELATED; 1.
DR PANTHER; PTHR12143:SF39; SECRETED PROTEIN-RELATED; 1.
DR Pfam; PF07971; Glyco_hydro_92; 1.
DR Pfam; PF17678; Glyco_hydro_92N; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Reference proteome {ECO:0000313|Proteomes:UP000000927};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..725
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003071710"
FT DOMAIN 35..221
FT /note="Glycosyl hydrolase family 92 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF17678"
FT DOMAIN 251..712
FT /note="Glycosyl hydrolase family 92"
FT /evidence="ECO:0000259|Pfam:PF07971"
SQ SEQUENCE 725 AA; 80625 MW; 34067EFEC7553018 CRC64;
MKCLNKFILA LTMTAVSGQV MAADACQHKN EFTNYVNPWI GTGGHGHVFL GANVPFGVIQ
LGPTEHTHGW DWCSGYHISD SVLVGFGHTH LSGTGIGDLG DIGFLPVAHC SATETKFSHA
NESVRPGYYA IRLQQPNVFV ELTATKRVGF HRYTFGADNH KGMLRIDLRQ GTGWDNWRKS
GFSVESPTMV TGFRQSSGWA RNQHVFFAAE FSTPVKVKKQ VGDSIMVLTF EDISKPVMVK
CAISAVSVED AKANLKAELP GWDFKATVAA ANQAWNDELG KIDVDTDDET VRTIFYTALY
HTMTAPSVFS DVTGNYRGAD GKVHHGDFTN YTTFSLWDTY RAAHPLMTLI HPEKQKDMAA
TFQHIFEQQG KLPVWHLMGN ETDCMVGNPG AAVLADMVLK GFVTDKEAAF NAMKTSAMLD
ERSMDLLKKY GYLPYDKDST FQTVAKGLEY ALADDCIAKV AKLLGKKADY KYFYNRSRGY
KHYFDRKTLF MRGRGSDGSF HEPFNPFKSV HTADDYTEGN AWQYTWLVPH DVHGLVSLFP
SEKRFVEKFD SLFIVSGDMG AEASPDISGL IGQYAHGNEP SHHILYMYNY VGQPWKAAKL
LRQTMSELYF NDFDGLSGNE DVGQMSAWYV MSSLGLYQVE PAGGKYIIGS PLFNEAKVNV
GGGKTFTVKA HNNSKENIYV QSAKLNGKPY AKSYLMFQDI VKGGVLELEM GNQPSAWGTQ
IKNRP
//
