ID D5EVS3_PRER2 Unreviewed; 329 AA.
AC D5EVS3;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=L-ornithine N(alpha)-acyltransferase {ECO:0000256|ARBA:ARBA00039866};
DE EC=2.3.2.30 {ECO:0000256|ARBA:ARBA00039058};
GN Name=phyA {ECO:0000313|EMBL:ADE82274.1};
GN OrderedLocusNames=PRU_2322 {ECO:0000313|EMBL:ADE82274.1};
OS Prevotella ruminicola (strain ATCC 19189 / JCM 8958 / 23).
OC Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Prevotellaceae;
OC Xylanibacter.
OX NCBI_TaxID=264731 {ECO:0000313|EMBL:ADE82274.1, ECO:0000313|Proteomes:UP000000927};
RN [1] {ECO:0000313|EMBL:ADE82274.1, ECO:0000313|Proteomes:UP000000927}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19189 / JCM 8958 / 23 {ECO:0000313|Proteomes:UP000000927};
RX PubMed=20585943; DOI=10.1007/s00248-010-9692-8;
RG North American Consortium for Rumen Bacteria;
RA Purushe J., Fouts D.E., Morrison M., White B.A., Mackie R.I.,
RA Coutinho P.M., Henrissat B., Nelson K.E.;
RT "Comparative genome analysis of Prevotella ruminicola and Prevotella
RT bryantii: insights into their environmental niche.";
RL Microb. Ecol. 60:721-729(2010).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a (3R)-hydroxyacyl-[ACP] + L-ornithine = a lyso-ornithine
CC lipid + H(+) + holo-[ACP]; Xref=Rhea:RHEA:20633, Rhea:RHEA-COMP:9685,
CC Rhea:RHEA-COMP:9945, ChEBI:CHEBI:15378, ChEBI:CHEBI:46911,
CC ChEBI:CHEBI:64479, ChEBI:CHEBI:78827, ChEBI:CHEBI:138482;
CC EC=2.3.2.30; Evidence={ECO:0000256|ARBA:ARBA00036203};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:20634;
CC Evidence={ECO:0000256|ARBA:ARBA00036203};
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- SIMILARITY: Belongs to the acetyltransferase family. OlsB subfamily.
CC {ECO:0000256|ARBA:ARBA00038095}.
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DR EMBL; CP002006; ADE82274.1; -; Genomic_DNA.
DR RefSeq; WP_013064261.1; NC_014033.1.
DR AlphaFoldDB; D5EVS3; -.
DR STRING; 264731.PRU_2322; -.
DR GeneID; 69977359; -.
DR KEGG; pru:PRU_2322; -.
DR eggNOG; COG3176; Bacteria.
DR HOGENOM; CLU_033329_0_0_10; -.
DR Proteomes; UP000000927; Chromosome.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR PANTHER; PTHR37323; GCN5-RELATED N-ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR37323:SF1; L-ORNITHINE N(ALPHA)-ACYLTRANSFERASE; 1.
DR Pfam; PF13444; Acetyltransf_5; 1.
DR SUPFAM; SSF55729; Acyl-CoA N-acyltransferases (Nat); 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Lipid biosynthesis {ECO:0000256|ARBA:ARBA00022516};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00022516};
KW Reference proteome {ECO:0000313|Proteomes:UP000000927};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 329 AA; 37822 MW; 29AF296A2E3ADD00 CRC64;
MEQEIIQPIA KEVLKSELTP DRQLRMTNKS HNEIYIITAH NAPNVMKEIG RLREIAFREA
GGGTGKSMDI DEFDTCDNCY KQLIVWNPEA EEIIGGYRYL LGTDWEYDEK GQPILATSHM
FHFSDRFIKD YAPWTIELGR SFVSLPYQSS RMGAKSLFAL DNLWDGLGAL TVIKPNVKYF
FGKMTMYPSY IRKGRDMILY FLKKHFDDKD KLIIPMKPLE LETDPKELES LFGGTSFKDD
YRVLNGEIRK LGYNIPPLVN AYMSLSPTMK LFGTAINYGF GDVEETGILI AVDEILEEKR
VRHIDSFIKE HPEALKITSG ANQVIYKEK
//
