ID D5G555_TUBMM Unreviewed; 1249 AA.
AC D5G555;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 24-JAN-2024, entry version 57.
DE SubName: Full=(Perigord truffle) hypothetical protein {ECO:0000313|EMBL:CAZ79640.1};
GN ORFNames=GSTUM_00000261001 {ECO:0000313|EMBL:CAZ79640.1};
OS Tuber melanosporum (strain Mel28) (Perigord black truffle).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes;
OC Pezizales; Tuberaceae; Tuber.
OX NCBI_TaxID=656061 {ECO:0000313|EMBL:CAZ79640.1, ECO:0000313|Proteomes:UP000006911};
RN [1] {ECO:0000313|EMBL:CAZ79640.1, ECO:0000313|Proteomes:UP000006911}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mel28 {ECO:0000313|EMBL:CAZ79640.1,
RC ECO:0000313|Proteomes:UP000006911};
RX PubMed=20348908; DOI=10.1038/nature08867;
RA Martin F., Kohler A., Murat C., Balestrini R., Coutinho P.M., Jaillon O.,
RA Montanini B., Morin E., Noel B., Percudani R., Porcel B., Rubini A.,
RA Amicucci A., Amselem J., Anthouard V., Arcioni S., Artiguenave F.,
RA Aury J.M., Ballario P., Bolchi A., Brenna A., Brun A., Buee M.,
RA Cantarel B., Chevalier G., Couloux A., Da Silva C., Denoeud F.,
RA Duplessis S., Ghignone S., Hilselberger B., Iotti M., Marcais B., Mello A.,
RA Miranda M., Pacioni G., Quesneville H., Riccioni C., Ruotolo R.,
RA Splivallo R., Stocchi V., Tisserant E., Viscomi A.R., Zambonelli A.,
RA Zampieri E., Henrissat B., Lebrun M.H., Paolocci F., Bonfante P.,
RA Ottonello S., Wincker P.;
RT "Perigord black truffle genome uncovers evolutionary origins and mechanisms
RT of symbiosis.";
RL Nature 464:1033-1038(2010).
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex. Involved in pre-tRNA
CC splicing, probably by affecting the interaction of pre-tRNA with
CC splicing endonuclease. {ECO:0000256|ARBA:ARBA00025147}.
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DR EMBL; FN429996; CAZ79640.1; -; Genomic_DNA.
DR RefSeq; XP_002835483.1; XM_002835437.1.
DR AlphaFoldDB; D5G555; -.
DR STRING; 656061.D5G555; -.
DR EnsemblFungi; CAZ79640; CAZ79640; GSTUM_00000261001.
DR GeneID; 9186338; -.
DR KEGG; tml:GSTUM_00000261001; -.
DR eggNOG; KOG2020; Eukaryota.
DR HOGENOM; CLU_003712_0_0_1; -.
DR InParanoid; D5G555; -.
DR OMA; IAKRSWG; -.
DR OrthoDB; 2721902at2759; -.
DR Proteomes; UP000006911; Unassembled WGS sequence.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR045478; Exportin-5_C.
DR InterPro; IPR045065; XPO1/5.
DR PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR PANTHER; PTHR11223:SF3; EXPORTIN-5; 1.
DR Pfam; PF19273; Exportin-5; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006911};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 132..197
FT /note="Exportin-1/Importin-beta-like"
FT /evidence="ECO:0000259|Pfam:PF08389"
FT DOMAIN 359..1203
FT /note="Exportin-5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF19273"
FT REGION 1..31
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1212..1249
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 16..31
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1249 AA; 140419 MW; 86A5C05137E3B8F2 CRC64;
MNGGGVPGDA VGSPTTNGGG PANGRALQQP QPLDQIKQAL QIVYDPHSSN DSRKQAGAFL
ESAKSDKEAP YHGFTLACDR GHDAVVRHFG LLLLEQAVRF SWVDYTAEES GMVRGWVLSL
AENVKIDGRD PVYLRNKIAQ LWVEVAKRSW ASEWLDMDEL LVRLWDNSTQ QGNPAQRDLV
LSILENLVED VFNREDSVAG IRNTPLSKAC IDIFTPLDVL KENFPGREPS AVLRCGEGGW
LTRLTEMLEK CLEAGVNGNT EVEACAVKVL GTLKACMSWA IPKAIAAAKI VETVGRALMV
EKISVQMVAV ECLHTLFTRI FFEDDDFQKI VCPMYYSQTV ELLANIFDWI RVDATDIDEE
RYLFLKRYAE MIANLGGFVE EKSGLMPVEA DLVGFMKLLF QICSHDSLSV SIPVMNAWTR
IIRKDLLSGH EAIGPLIPGL IALATARLIR YESVTDESNR SIIFLNEDLD TMPDRHAFLG
NYRRFCQSIV ECLVRKSPFD IFPYILAQAD ASLSDLCSKE PPFTAETYRK NSGPFLQLDA
HFTVVEASLR GYMKWIDTIG KNPTNNNSRN ELEQRLTEWC ERVLSMNFGD PMIRRRVIQL
MVTVSTSALD KKADLMLKIL EHVLLTRPPE YPANHAYTDA VKELMGVCTT EIQRLAMKMP
DHLMLVYEGL QTKINEIIST ENVDDRTRIA FHTFLFTINH RTKNIDPAIR QSRLESYIHP
VRETWRDPGL TESLQTFQGF CTILGLDKVQ EYLISRRVNE IPDFTKHVLD TEGQALQNEL
AEKFKALPIR ATKAFLAVST EQLRKPSNAY NIACALWHES IPMILPNLLQ FLTHAHAFHN
AGNWAGLQPE LQAVIRKILT DRFWQAGIST GSRDEFYENV TKTKTTMEGL ASSIRGAIRM
VREACYSILW CMSRLDVHFY GLNELPGPLA LALFADAHAL SSHQMSILLN MTRYIIDDCP
TTLRAHFLTP LLASLFTQVD RKISGEWDEL IRKGQISLGE DKLAEEMKEE SILRQLTYTA
VLIVAGLLDP QRPGETVNTN SGFLDQLALP EMQAAGPGEQ TMREFILSSD CVLEPLILFC
THALRMRDSR CCGIIIRVFR SIVPEFQADR ADIREFICRE VFIAAIEALH TDYFVDVQKD
LAQLIAAIFT LYSPTSGTPR SLLLNLPGLT EAKVDACYKK LTAAGSTRQQ RALILELLDG
LRGVAISEKG KLQRPQVGKQ RSQAEKRQQQ QYAEKRESPD LGGVADMFA
//
