ID D5H1X4_LACCS Unreviewed; 510 AA.
AC D5H1X4;
DT 15-JUN-2010, integrated into UniProtKB/TrEMBL.
DT 15-JUN-2010, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:CBL50009.1};
GN OrderedLocusNames=LCRIS_00562 {ECO:0000313|EMBL:CBL50009.1};
OS Lactobacillus crispatus (strain ST1).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=748671 {ECO:0000313|EMBL:CBL50009.1, ECO:0000313|Proteomes:UP000002371};
RN [1] {ECO:0000313|EMBL:CBL50009.1, ECO:0000313|Proteomes:UP000002371}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ST1 {ECO:0000313|EMBL:CBL50009.1,
RC ECO:0000313|Proteomes:UP000002371};
RX PubMed=20435723; DOI=10.1128/JB.00399-10;
RA Ojala T., Kuparinen V., Koskinen J.P., Alatalo E., Holm L., Auvinen P.,
RA Edelman S., Westerlund-Wikstrom B., Korhonen T.K., Paulin L., Kankainen M.;
RT "Genome sequence of Lactobacillus crispatus ST1.";
RL J. Bacteriol. 192:3547-3548(2010).
RN [2]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ST1;
RA Ojala T., Kuparinen V., Koskinen J.P., Alatalo E., Holm L., Auvinen P.,
RA Edelman S., Westerlund-Wikstroem B., Korhonen T.K., Paulin L.,
RA Kankainen M.;
RT "Genome Sequence of Lactobacillus crispatus ST1.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the BlaI transcriptional regulatory family.
CC {ECO:0000256|ARBA:ARBA00011046}.
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DR EMBL; FN692037; CBL50009.1; -; Genomic_DNA.
DR RefSeq; WP_013085979.1; NC_014106.1.
DR AlphaFoldDB; D5H1X4; -.
DR KEGG; lcr:LCRIS_00562; -.
DR PATRIC; fig|748671.3.peg.542; -.
DR eggNOG; COG2865; Bacteria.
DR HOGENOM; CLU_024970_0_1_9; -.
DR Proteomes; UP000002371; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR Gene3D; 3.30.565.60; -; 1.
DR Gene3D; 3.30.950.30; Schlafen, AAA domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR005650; BlaI_family.
DR InterPro; IPR025831; RecG_C.
DR InterPro; IPR038475; RecG_C_sf.
DR InterPro; IPR007421; Schlafen_AlbA_2_dom.
DR InterPro; IPR038461; Schlafen_AlbA_2_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR30595:SF6; ATP-DEPENDENT DNA HELICASE; 1.
DR PANTHER; PTHR30595; GLPR-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF13749; HATPase_c_4; 1.
DR Pfam; PF03965; Penicillinase_R; 1.
DR Pfam; PF04326; SLFN_AlbA_2; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE 3: Inferred from homology;
FT DOMAIN 20..141
FT /note="Schlafen AlbA-2"
FT /evidence="ECO:0000259|Pfam:PF04326"
FT DOMAIN 340..403
FT /note="ATP-dependent DNA helicase RecG C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13749"
SQ SEQUENCE 510 AA; 58672 MW; AD0646E7EB2528B2 CRC64;
MDFLNFKAIT QTGNFKTPSE NENIEYKEAS WKLPKSFWET VSSFANTSGG IIVLGIAEDK
SKHEFSITGV DNVEDIETQI FNDNNNISCL NRPVIQNNDV QISFFQNKTI IQVIIHPEPF
NTRPITAFGK AYIRTGDGDQ VATKEQLKYF TVESQSEINT HLLPSTYTIE DLDAESIKEY
RKIIEEKGII NTNSQLSDQD FLYSIGVFRK DRLSNSNEYH LTDSGLLFFG KYISITDRFP
RFQLDYQQYN SDNSTNWNDR VSAGDMNYPT LNIFSFYNLV LAKIETNIPD PFIQGSDLSR
TSYHNDLIIA AKEALVNCLM HSYYDGMVGV KIVDRPSYFE FTNPGTMRVS KESFLRGQYS
SIRNTEIASL FRRIGVSETA ASGGPRILNT VLQNNLNDPE INIDYEINTT RIRIFKTFAI
DNQEKLTEPE KFIMSFASRN PNFSINDIVK DPQNHFGKQT TIRKYVNSLV EKHLLSNEKI
GKKYIYNLQK NNDYLNRVKH LKHLEDNLLK
//
