ID D5P330_9MYCO Unreviewed; 540 AA.
AC D5P330;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 65.
DE SubName: Full=Acyl transferase domain protein {ECO:0000313|EMBL:EFG79508.1};
DE Flags: Fragment;
GN Name=pks7 {ECO:0000313|EMBL:EFG79508.1};
GN ORFNames=HMPREF0591_0574 {ECO:0000313|EMBL:EFG79508.1};
OS Mycobacterium parascrofulaceum ATCC BAA-614.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium simiae complex.
OX NCBI_TaxID=525368 {ECO:0000313|EMBL:EFG79508.1, ECO:0000313|Proteomes:UP000003653};
RN [1] {ECO:0000313|EMBL:EFG79508.1, ECO:0000313|Proteomes:UP000003653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-614 {ECO:0000313|EMBL:EFG79508.1,
RC ECO:0000313|Proteomes:UP000003653};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Lipid metabolism. {ECO:0000256|ARBA:ARBA00005189}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFG79508.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; ADNV01000069; EFG79508.1; -; Genomic_DNA.
DR AlphaFoldDB; D5P330; -.
DR eggNOG; COG3321; Bacteria.
DR HOGENOM; CLU_554985_0_0_11; -.
DR Proteomes; UP000003653; Unassembled WGS sequence.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.30.70.3290; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR PANTHER; PTHR43775; FATTY ACID SYNTHASE; 1.
DR PANTHER; PTHR43775:SF51; PHENOLPHTHIOCEROL_PHTHIOCEROL POLYKETIDE SYNTHASE SUBUNIT E; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF00550; PP-binding; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00823; PKS_PP; 1.
DR SMART; SM01294; PKS_PP_betabranch; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 1.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EFG79508.1}.
FT DOMAIN 388..463
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EFG79508.1"
SQ SEQUENCE 540 AA; 56742 MW; 706043488804F0C6 CRC64;
AAGVVVGRAG PAGRTGFAFP GQGSQWPGMG RQLHQHFPAF ADAFDEAAAA MDAHLRTPLR
EVMWGTDAES LRRTEFAQPA LFVLEVALAA LWRSWGVTPD VVLGHSVGEI AAAHVAGVLS
LPDASRIVAA RGELMGRLPA GGTMVAVSAG EAEVAPMLTD GVGIAAVNGP DAVVLSGERQ
AVAALADRLS GTGRRTHRLA VSHAFHSALM EPMLDEFTHR VADIEPRQPR ICLISNVSGD
PAGPGYGSAR YWVEHVRRPV RFLAGVRAAE AMGVTAFVEV GPGAALSAAV DQSLTTERPI
SVVTLPKAGP EAESVLTAAG RLFAAGLDIG WPAALAGSGG RRVDLPTYGF ARQRFWLGGG
RDALPAKAGR VPDLAGQLHG LPPAEQQRRL VELVCEHAAA VAGHADGRAV DRDRAFADLG
FDSLTGVELR NRLTAATGLA LSRTLIFDYP TPAALADRLR QQLFRGDGDE SDEDKLWSSL
RRIPLAELRR TGLLDKLLLL AGEPESVANE PVTGDDPIDS LSADALIAMA LNSTEEDGKR
//
