ID D5P9X4_9MYCO Unreviewed; 228 AA.
AC D5P9X4;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Glutamine amidotransferase, class I {ECO:0000313|EMBL:EFG77119.1};
DE EC=4.1.3.27 {ECO:0000313|EMBL:EFG77119.1};
GN Name=trpG {ECO:0000313|EMBL:EFG77119.1};
GN ORFNames=HMPREF0591_2968 {ECO:0000313|EMBL:EFG77119.1};
OS Mycobacterium parascrofulaceum ATCC BAA-614.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae;
OC Mycobacterium; Mycobacterium simiae complex.
OX NCBI_TaxID=525368 {ECO:0000313|EMBL:EFG77119.1, ECO:0000313|Proteomes:UP000003653};
RN [1] {ECO:0000313|EMBL:EFG77119.1, ECO:0000313|Proteomes:UP000003653}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-614 {ECO:0000313|EMBL:EFG77119.1,
RC ECO:0000313|Proteomes:UP000003653};
RA Muzny D., Qin X., Deng J., Jiang H., Liu Y., Qu J., Song X.-Z., Zhang L.,
RA Thornton R., Coyle M., Francisco L., Jackson L., Javaid M., Korchina V.,
RA Kovar C., Mata R., Mathew T., Ngo R., Nguyen L., Nguyen N., Okwuonu G.,
RA Ongeri F., Pham C., Simmons D., Wilczek-Boney K., Hale W., Jakkamsetti A.,
RA Pham P., Ruth R., San Lucas F., Warren J., Zhang J., Zhao Z., Zhou C.,
RA Zhu D., Lee S., Bess C., Blankenburg K., Forbes L., Fu Q., Gubbala S.,
RA Hirani K., Jayaseelan J.C., Lara F., Munidasa M., Palculict T., Patil S.,
RA Pu L.-L., Saada N., Tang L., Weissenberger G., Zhu Y., Hemphill L.,
RA Shang Y., Youmans B., Ayvaz T., Ross M., Santibanez J., Aqrawi P.,
RA Gross S., Joshi V., Fowler G., Nazareth L., Reid J., Worley K.,
RA Petrosino J., Highlander S., Gibbs R.;
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EFG77119.1}.
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DR EMBL; ADNV01000229; EFG77119.1; -; Genomic_DNA.
DR RefSeq; WP_007167000.1; NZ_GG770553.1.
DR AlphaFoldDB; D5P9X4; -.
DR eggNOG; COG0512; Bacteria.
DR HOGENOM; CLU_014340_1_2_11; -.
DR Proteomes; UP000003653; Unassembled WGS sequence.
DR GO; GO:0004049; F:anthranilate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0008652; P:amino acid biosynthetic process; IEA:UniProt.
DR GO; GO:0009073; P:aromatic amino acid family biosynthetic process; IEA:UniProt.
DR GO; GO:0044271; P:cellular nitrogen compound biosynthetic process; IEA:UniProt.
DR GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0018130; P:heterocycle biosynthetic process; IEA:UniProt.
DR CDD; cd01743; GATase1_Anthranilate_Synthase; 1.
DR Gene3D; 3.40.50.880; -; 1.
DR InterPro; IPR029062; Class_I_gatase-like.
DR InterPro; IPR017926; GATASE.
DR InterPro; IPR006221; TrpG/PapA_dom.
DR NCBIfam; TIGR00566; trpG_papA; 1.
DR PANTHER; PTHR43418:SF4; MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN; 1.
DR PANTHER; PTHR43418; MULTIFUNCTIONAL TRYPTOPHAN BIOSYNTHESIS PROTEIN-RELATED; 1.
DR Pfam; PF00117; GATase; 1.
DR PRINTS; PR00097; ANTSNTHASEII.
DR PRINTS; PR00099; CPSGATASE.
DR PRINTS; PR00096; GATASE.
DR SUPFAM; SSF52317; Class I glutamine amidotransferase-like; 1.
DR PROSITE; PS51273; GATASE_TYPE_1; 1.
PE 4: Predicted;
KW Glutamine amidotransferase {ECO:0000256|PROSITE-ProRule:PRU00605,
KW ECO:0000313|EMBL:EFG77119.1}; Lyase {ECO:0000313|EMBL:EFG77119.1};
KW Transferase {ECO:0000313|EMBL:EFG77119.1}.
FT DOMAIN 4..189
FT /note="Glutamine amidotransferase"
FT /evidence="ECO:0000259|Pfam:PF00117"
FT ACT_SITE 83
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT ACT_SITE 172
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
FT ACT_SITE 174
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00605"
SQ SEQUENCE 228 AA; 24455 MW; 1E5E9AFFCF4CC998 CRC64;
MRILVVDNYD SFVFNLVQYL GQLGVEAEVW RNDDARLSDE AAVAARFDGV LLSPGPGTPE
RAGASIALVG ACAAERTPLL GVCLGHQAIG VAFGATVDRA PELLHGKTSS VFHTNAGVLQ
GLPDPFTATR YHSLTILPES LPPVLEVTAR TRGGVIMGVR HSELPIHGVQ FHPESILTEG
GHRMLANWLA YCGWARDDTL VRRLENEVRA AVQPYFPADP PATGRTSA
//
