ID D5U319_THEAM Unreviewed; 651 AA.
AC D5U319;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 62.
DE SubName: Full=KH-domain/beta-lactamase-domain protein {ECO:0000313|EMBL:ADG91519.1};
GN OrderedLocusNames=Tagg_1253 {ECO:0000313|EMBL:ADG91519.1};
OS Thermosphaera aggregans (strain DSM 11486 / M11TL).
OC Archaea; Thermoproteota; Thermoprotei; Desulfurococcales;
OC Desulfurococcaceae; Thermosphaera.
OX NCBI_TaxID=633148 {ECO:0000313|EMBL:ADG91519.1, ECO:0000313|Proteomes:UP000002376};
RN [1] {ECO:0000313|EMBL:ADG91519.1, ECO:0000313|Proteomes:UP000002376}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11486 / M11TL {ECO:0000313|Proteomes:UP000002376};
RX PubMed=21304709;
RA Spring S., Rachel R., Lapidus A., Davenport K., Tice H., Copeland A.,
RA Cheng J.F., Lucas S., Chen F., Nolan M., Bruce D., Goodwin L., Pitluck S.,
RA Ivanova N., Mavromatis K., Ovchinnikova G., Pati A., Chen A.,
RA Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.C., Brettin T.,
RA Detter J.C., Tapia R., Han C., Heimerl T., Weikl F., Brambilla E.,
RA Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Thermosphaera aggregans type strain (M11TL).";
RL Stand. Genomic Sci. 2:245-259(2010).
RN [2] {ECO:0000313|Proteomes:UP000002376}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11486 / M11TL {ECO:0000313|Proteomes:UP000002376};
RX DOI=10.4056/sigs.821804;
RA Spring S., Rachel R., Lapidus A., Davenport K., Tice H., Copeland A.,
RA Cheng J.-F., Lucas S., Chen F., Nolan M., Bruce D., Goodwin L., Pitluck S.,
RA Ivanova N., Mavromatis K., Ovchinnikova G., Pati A., Chen A.,
RA Palaniappan K., Land M., Hauser L., Chang Y.-J., Jeffries C.C., Brettin T.,
RA Detter J.C., Tapia R., Han C., Heimerl T., Weikl F., Brambilla E.,
RA Goker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.-P.;
RT "Complete genome sequence of Thermosphaera aggregans type strain
RT (M11TLT).";
RL Stand. Genomic Sci. 2:245-259(2010).
RN [3]
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=DSM 11486;
RG US DOE Joint Genome Institute (JGI-PGF);
RA Spring S., Lapidus A., Munk C., Schroeder M., Glavina Del Rio T., Tice H.,
RA Copeland A., Cheng J.-F., Lucas S., Chen F., Nolan M., Bruce D.,
RA Goodwin L., Pitluck S., Ivanova N., Mavromatis K., Ovchinnikova G.,
RA Pati A., Chen A., Palaniappan K., Land M., Hauser L., Chang Y.-J.,
RA Jeffries C.C., Brettin T., Detter J.C., Tapia R., Han C., Chain P.,
RA Heimerl T., Weik F., Goker M., Rachel R., Bristow J., Eisen J.A.,
RA Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.-P.;
RT "Complete genome sequence of Thermosphaera aggregans type strain (M11TL).";
RL Submitted (FEB-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP001939; ADG91519.1; -; Genomic_DNA.
DR RefSeq; WP_013130112.1; NC_014160.1.
DR AlphaFoldDB; D5U319; -.
DR STRING; 633148.Tagg_1253; -.
DR GeneID; 9166296; -.
DR KEGG; tag:Tagg_1253; -.
DR eggNOG; arCOG00543; Archaea.
DR HOGENOM; CLU_009673_5_1_2; -.
DR OrthoDB; 7155at2157; -.
DR Proteomes; UP000002376; Chromosome.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR CDD; cd22532; KH-II_CPSF_arch_rpt1; 1.
DR CDD; cd16295; TTHA0252-CPSF-like_MBL-fold; 1.
DR Gene3D; 3.30.300.20; -; 1.
DR Gene3D; 3.30.300.230; -; 1.
DR Gene3D; 3.40.50.10890; -; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR019975; aCPSF1.
DR InterPro; IPR022712; Beta_Casp.
DR InterPro; IPR033769; KH_arc.
DR InterPro; IPR015946; KH_dom-like_a/b.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR011108; RMMBL.
DR NCBIfam; TIGR03675; arCOG00543; 1.
DR PANTHER; PTHR11203; CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER; 1.
DR PANTHER; PTHR11203:SF37; INTEGRATOR COMPLEX SUBUNIT 11; 1.
DR Pfam; PF10996; Beta-Casp; 1.
DR Pfam; PF17214; KH_7; 1.
DR Pfam; PF16661; Lactamase_B_6; 1.
DR Pfam; PF07521; RMMBL; 1.
DR SMART; SM01027; Beta-Casp; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002376}.
FT DOMAIN 200..423
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
FT DOMAIN 428..551
FT /note="Beta-Casp"
FT /evidence="ECO:0000259|SMART:SM01027"
SQ SEQUENCE 651 AA; 72963 MW; F1BDC99E45933120 CRC64;
MKIDKSVLNK NKLALLGSIV QEIPPELELS NIEFEGPSIV VYVRNRKAIS EHLDLAQNIA
KKVRKRVVIR VSTESRLPVD EAKKKILEIA PREAGLDPNG IYFDETSGEV WVKVEKPGLI
VGRGNYVRHK ILAETGWRAV PMRASPLESK VLREVVAGTL KQSEYRLEFL RRLGDRIHRD
VIFKNNYVRI TALGGFREVG RSSILVETRE SRLLLDMGIN TGVMDDPFKA FPYIDVDSLK
LEELDGVIVT HSHLDHVGLV PILYKYGYRG PLYVTKPTRE LMIVMLKDLI EVSRRSGRYL
PFTEKDLTTM ILHTITVEYD EVTDVAPDIK LTMYNAGHIL GSAIVHLHVG MGLHNIVYTG
DFKYASTRLL DRANTEFPRV ETLIMESTYG SAKQQNRLEA EAELVNIVKR TVERQGIVLI
PVFAVGRGQE IILILNEAMK NGLIPKLNVY VEGLVNEVTA IHTQYPEYLS RSIREAIYRG
ENPFTADWLK ILESGVARPD IVEDRPSVII ATSGMLTGGP AVDYLKLLAS DPRNSLVFVG
YQAEGTLGRK IKDGMRELTM VVENKVEAVK IDLEVYSIDG FSGHSDQAEL VKYAQSIKPK
PRKIILNHGE PSAIDTLARL LRKALLAPGT GYTSLPEIYT PSNLDTVHLT S
//
