ID D5UPJ1_TSUPD Unreviewed; 1003 AA.
AC D5UPJ1;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 60.
DE SubName: Full=Glycoside hydrolase family 38 {ECO:0000313|EMBL:ADG78747.1};
GN OrderedLocusNames=Tpau_2136 {ECO:0000313|EMBL:ADG78747.1};
OS Tsukamurella paurometabola (strain ATCC 8368 / DSM 20162 / CCUG 35730 / CIP
OS 100753 / JCM 10117 / KCTC 9821 / NBRC 16120 / NCIMB 702349 / NCTC 13040)
OS (Corynebacterium paurometabolum).
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Tsukamurellaceae;
OC Tsukamurella.
OX NCBI_TaxID=521096 {ECO:0000313|EMBL:ADG78747.1, ECO:0000313|Proteomes:UP000001213};
RN [1] {ECO:0000313|Proteomes:UP000001213}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8368 / DSM 20162 / CCUG 35730 / CIP 100753 / JCM 10117 /
RC KCTC 9821 / NBRC 16120 / NCIMB 702349 / NCTC 13040
RC {ECO:0000313|Proteomes:UP000001213};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA Mikhailova N., Munk A.C., Brettin T., Detter J.C., Tapia R., Han C.,
RA Larimer F., Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P.,
RA Woyke T., Wu D., Jando M., Brambilla E., Klenk H.-P., Eisen J.A.;
RT "The complete chromosome of Tsukamurella paurometabola DSM 20162.";
RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADG78747.1, ECO:0000313|Proteomes:UP000001213}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8368 / DSM 20162 / CCUG 35730 / CIP 100753 / JCM 10117 /
RC KCTC 9821 / NBRC 16120 / NCIMB 702349 / NCTC 13040
RC {ECO:0000313|Proteomes:UP000001213};
RX PubMed=21886861;
RA Munk A.C., Lapidus A., Lucas S., Nolan M., Tice H., Cheng J.F.,
RA Del Rio T.G., Goodwin L., Pitluck S., Liolios K., Huntemann M., Ivanova N.,
RA Mavromatis K., Mikhailova N., Pati A., Chen A., Palaniappan K., Tapia R.,
RA Han C., Land M., Hauser L., Chang Y.J., Jeffries C.D., Brettin T.,
RA Yasawong M., Brambilla E.M., Rohde M., Sikorski J., Goker M., Detter J.C.,
RA Woyke T., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P.,
RA Kyrpides N.C., Klenk H.P.;
RT "Complete genome sequence of Tsukamurella paurometabola type strain (no.
RT 33).";
RL Stand. Genomic Sci. 4:342-351(2011).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 38 family.
CC {ECO:0000256|ARBA:ARBA00009792}.
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DR EMBL; CP001966; ADG78747.1; -; Genomic_DNA.
DR RefSeq; WP_013126769.1; NC_014158.1.
DR AlphaFoldDB; D5UPJ1; -.
DR STRING; 521096.Tpau_2136; -.
DR CAZy; GH38; Glycoside Hydrolase Family 38.
DR KEGG; tpr:Tpau_2136; -.
DR eggNOG; COG0383; Bacteria.
DR HOGENOM; CLU_003442_0_1_11; -.
DR Proteomes; UP000001213; Chromosome.
DR GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR CDD; cd10789; GH38N_AMII_ER_cytosolic; 1.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR Gene3D; 1.20.1270.50; Glycoside hydrolase family 38, central domain; 1.
DR InterPro; IPR011013; Gal_mutarotase_sf_dom.
DR InterPro; IPR041147; GH38_C.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR011682; Glyco_hydro_38_C.
DR InterPro; IPR015341; Glyco_hydro_38_cen.
DR InterPro; IPR037094; Glyco_hydro_38_cen_sf.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR InterPro; IPR028995; Glyco_hydro_57/38_cen_sf.
DR PANTHER; PTHR46017; ALPHA-MANNOSIDASE 2C1; 1.
DR PANTHER; PTHR46017:SF1; ALPHA-MANNOSIDASE 2C1; 1.
DR Pfam; PF09261; Alpha-mann_mid; 1.
DR Pfam; PF17677; Glyco_hydro38C2; 1.
DR Pfam; PF07748; Glyco_hydro_38C; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR SMART; SM00872; Alpha-mann_mid; 1.
DR SUPFAM; SSF88688; Families 57/38 glycoside transferase middle domain; 1.
DR SUPFAM; SSF74650; Galactose mutarotase-like; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000313|EMBL:ADG78747.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000001213}.
FT DOMAIN 523..601
FT /note="Glycoside hydrolase family 38 central"
FT /evidence="ECO:0000259|SMART:SM00872"
SQ SEQUENCE 1003 AA; 110011 MW; A893FEF8212967F1 CRC64;
MHDETSLTIG RVNRVLGERI RPAIHSARIP LDVAANHLPG EPIPPAAGLR LDYSPFADDR
RWGPAWGTTW FRLRGDVPAE WAGKQVEALI DLGFDVNQTG FQCEGLAYRC GLDGAPVPVK
GINPRNQAVA VADRATGGEQ VELFVEAAAN PVILDYHPFL PTRQGDVLTS SPEPLYRVRA
MDLAVFEPEV FALALDVEVL LELQAELPET QPRRMRILQA LDDALDVLDL QRIVETAPAA
RAALVQVLAA PADASAHRIA AIGHSHIDSA WLWPLRETIR KVARTTASMT TLLDEQPQYS
YGMSSAQQYA WVKEHRPEVW ERIRAAVADG RFLPLGGMWV EADTVMPTGE SLARQFSYGQ
RFFEREFGIR SRGVWLPDSF GYSPALPQLM RRAGFDWFFT QKISWNQRNV FPHHTFDWEG
IDGTRVFTHF PPMDTYCSSL SGAEVARAAR QFKESRVATR SIAPVGYGDG GGGTTREMIG
KAERLANLEG SARVHWVHPD EFFDAAKAEL PDPAVWVGEL YLELHRGTLT SQHATKATHR
RCEQALLEAE LWAATAAVQQ GLAYPYGDLD ALWEQVLLHQ FHDILPGTSI AWVHREAVAV
LTDVLARARG LAADARRALA GDGGVDLVFR PVHTPVDAAG ALGAAPAAPP SGAVTLTPRA
GGYRLTNELI SVTVSKNGTI TSAIDLATGR EAIPDGRPAN LFQLHQDFPN AWDAWDIDRY
YRNRVDDLTA ATSITGDLTD GVAEVVVTRT FSESSLQQTI TLAPGSRTVM LRNRIDWHET
EKLLKLAFPL DVFARETAAE TQFGFQRRAT HVNTSWEAAK FETSMHRFVL AEEDGFGVAV
VNDSVYGYDT ARDDAQGAIT TTVRVSLLRA PRFPDPDTDH GVHEITVGLV VGADPAIATT
EGQRLNAPET VVRGAGPVAP LVTLDGEGIV ISAIKLADDR SGDVIVRLYE ALGRRARGSL
SVGFSHGGIR EVSLIEDEID DPRVGGDLDL RPFEVRTLRI SRR
//
