ID   D5VHC3_CAUST            Unreviewed;       314 AA.
AC   D5VHC3;
DT   13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT   13-JUL-2010, sequence version 1.
DT   27-MAR-2024, entry version 48.
DE   SubName: Full=Fatty acid desaturase {ECO:0000313|EMBL:ADG08781.1};
GN   OrderedLocusNames=Cseg_0261 {ECO:0000313|EMBL:ADG08781.1};
OS   Caulobacter segnis (strain ATCC 21756 / DSM 7131 / JCM 7823 / NBRC 15250 /
OS   LMG 17158 / TK0059) (Mycoplana segnis).
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Caulobacterales;
OC   Caulobacteraceae; Caulobacter.
OX   NCBI_TaxID=509190 {ECO:0000313|EMBL:ADG08781.1, ECO:0000313|Proteomes:UP000002629};
RN   [1] {ECO:0000313|Proteomes:UP000002629}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 21756 / DSM 7131 / JCM 7823 / NBRC 15250 / LMG 17158 /
RC   TK0059 {ECO:0000313|Proteomes:UP000002629};
RX   PubMed=21705585; DOI=10.1128/JB.05453-11;
RG   US DOE Joint Genome Institute;
RA   Brown P.J., Kysela D.T., Buechlein A., Hemmerich C., Brun Y.V.;
RT   "Genome sequences of eight morphologically diverse alphaproteobacteria.";
RL   J. Bacteriol. 193:4567-4568(2011).
CC   -!- SIMILARITY: Belongs to the fatty acid desaturase type 1 family.
CC       {ECO:0000256|ARBA:ARBA00009295}.
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DR   EMBL; CP002008; ADG08781.1; -; Genomic_DNA.
DR   RefSeq; WP_013077455.1; NC_014100.1.
DR   AlphaFoldDB; D5VHC3; -.
DR   STRING; 509190.Cseg_0261; -.
DR   KEGG; cse:Cseg_0261; -.
DR   eggNOG; COG3239; Bacteria.
DR   HOGENOM; CLU_052920_2_0_5; -.
DR   Proteomes; UP000002629; Chromosome.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0016717; F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water; IEA:UniProt.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProt.
DR   CDD; cd03510; Rhizobitoxine-FADS-like; 1.
DR   InterPro; IPR005804; FA_desaturase_dom.
DR   InterPro; IPR012171; Fatty_acid_desaturase.
DR   PANTHER; PTHR19353:SF19; DELTA(5) FATTY ACID DESATURASE C-RELATED; 1.
DR   PANTHER; PTHR19353; FATTY ACID DESATURASE 2; 1.
DR   Pfam; PF00487; FA_desaturase; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        56..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        186..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          52..287
FT                   /note="Fatty acid desaturase"
FT                   /evidence="ECO:0000259|Pfam:PF00487"
SQ   SEQUENCE   314 AA;  35171 MW;  CD8BA89832EF2887 CRC64;
     MAVATRVKPQ DLFTPEEWTR ISARSSWRGI ALVAHAWAVI VAAGALFVLF PNPLTYVLAV
     MLIGARQLGL AILMHEAAHG GLHPNLKVND WLGEWLCAAP IGASLERYRP YHLTHHKYAQ
     QAEDPDLVLS APFPTTRVSL RRKMVRDLTG QTFFKQRFGP LLGKAKGDTP RGAIVAGEVA
     RQAPFLLWNL GLLVVLSALG LWWAWLALWI VPMATWFPLV TRLRNIAEHA LVARDEPDPF
     RHARTTRANW VERALIAPYH VNFHAEHHMF MHTPCWNLPL AHRLLEQKGM TERMLTAPGY
     LSVLKAASSK AVAA
//