ID D5VR20_METIM Unreviewed; 259 AA.
AC D5VR20;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 55.
DE SubName: Full=Prephenate dehydratase {ECO:0000313|EMBL:ADG13023.1};
DE EC=4.2.1.51 {ECO:0000313|EMBL:ADG13023.1};
GN OrderedLocusNames=Metin_0353 {ECO:0000313|EMBL:ADG13023.1};
OS Methanocaldococcus infernus (strain DSM 11812 / JCM 15783 / ME).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanocaldococcaceae; Methanocaldococcus.
OX NCBI_TaxID=573063 {ECO:0000313|EMBL:ADG13023.1, ECO:0000313|Proteomes:UP000002061};
RN [1] {ECO:0000313|EMBL:ADG13023.1, ECO:0000313|Proteomes:UP000002061}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11812 / JCM 15783 / ME {ECO:0000313|Proteomes:UP000002061};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Munk A.C., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Woyke T.;
RT "Complete sequence of Methanocaldococcus infernus ME.";
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Amino-acid biosynthesis. {ECO:0000256|ARBA:ARBA00029440}.
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DR EMBL; CP002009; ADG13023.1; -; Genomic_DNA.
DR RefSeq; WP_013099769.1; NC_014122.1.
DR AlphaFoldDB; D5VR20; -.
DR STRING; 573063.Metin_0353; -.
DR GeneID; 9131355; -.
DR KEGG; mif:Metin_0353; -.
DR eggNOG; arCOG00255; Archaea.
DR HOGENOM; CLU_035008_0_2_2; -.
DR OrthoDB; 8755at2157; -.
DR Proteomes; UP000002061; Chromosome.
DR GO; GO:0004664; F:prephenate dehydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0009094; P:L-phenylalanine biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd04905; ACT_CM-PDT; 1.
DR CDD; cd13630; PBP2_PDT_1; 1.
DR Gene3D; 3.30.70.260; -; 1.
DR Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR InterPro; IPR045865; ACT-like_dom_sf.
DR InterPro; IPR002912; ACT_dom.
DR InterPro; IPR001086; Preph_deHydtase.
DR InterPro; IPR018528; Preph_deHydtase_CS.
DR PANTHER; PTHR21022; PREPHENATE DEHYDRATASE P PROTEIN; 1.
DR PANTHER; PTHR21022:SF19; PREPHENATE DEHYDRATASE-RELATED; 1.
DR Pfam; PF01842; ACT; 1.
DR Pfam; PF00800; PDT; 1.
DR SUPFAM; SSF55021; ACT-like; 1.
DR SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR PROSITE; PS51671; ACT; 1.
DR PROSITE; PS00858; PREPHENATE_DEHYDR_2; 1.
DR PROSITE; PS51171; PREPHENATE_DEHYDR_3; 1.
PE 4: Predicted;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Aromatic amino acid biosynthesis {ECO:0000256|ARBA:ARBA00023141};
KW Lyase {ECO:0000256|ARBA:ARBA00023239, ECO:0000313|EMBL:ADG13023.1};
KW Phenylalanine biosynthesis {ECO:0000256|ARBA:ARBA00023222}.
FT DOMAIN 1..170
FT /note="Prephenate dehydratase"
FT /evidence="ECO:0000259|PROSITE:PS51171"
FT DOMAIN 184..256
FT /note="ACT"
FT /evidence="ECO:0000259|PROSITE:PS51671"
SQ SEQUENCE 259 AA; 29760 MW; 8BE31B2D0B53A0E5 CRC64;
MKLYTLPKGT YTETAGKKIL KYLNAKLCYC QNIYEIFEKA KDDYGIVPIE NSIEGSVNLT
QDLLLEYDYK IVGETVLDIH HNLIGHSKEK IKIIYSHPQA LAQCRKYIKK HGWEVKAVES
TAKAVELASK NEEAGAIGSE GLAKLHGLKI LERNIEDYKN NKTRFIVIGK KEIDGNFNKY
KTSIVFELKE DKPGALYHIL KEFALREINL TRIESRPSKR MLGTYIFYID YEGLNLEVLE
SLKRYVSFLR VLGSYPILV
//
