ID D5VSX1_METIM Unreviewed; 378 AA.
AC D5VSX1;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 58.
DE SubName: Full=Putative RNA methylase {ECO:0000313|EMBL:ADG13674.1};
GN OrderedLocusNames=Metin_1016 {ECO:0000313|EMBL:ADG13674.1};
OS Methanocaldococcus infernus (strain DSM 11812 / JCM 15783 / ME).
OC Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC Methanocaldococcaceae; Methanocaldococcus.
OX NCBI_TaxID=573063 {ECO:0000313|EMBL:ADG13674.1, ECO:0000313|Proteomes:UP000002061};
RN [1] {ECO:0000313|EMBL:ADG13674.1, ECO:0000313|Proteomes:UP000002061}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11812 / JCM 15783 / ME {ECO:0000313|Proteomes:UP000002061};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Munk A.C., Detter J.C., Han C., Tapia R., Land M., Hauser L.,
RA Kyrpides N., Mikhailova N., Sieprawska-Lupa M., Whitman W.B., Woyke T.;
RT "Complete sequence of Methanocaldococcus infernus ME.";
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP002009; ADG13674.1; -; Genomic_DNA.
DR RefSeq; WP_013100419.1; NC_014122.1.
DR AlphaFoldDB; D5VSX1; -.
DR STRING; 573063.Metin_1016; -.
DR GeneID; 9132033; -.
DR KEGG; mif:Metin_1016; -.
DR eggNOG; arCOG00048; Archaea.
DR HOGENOM; CLU_032119_0_0_2; -.
DR OrthoDB; 7080at2157; -.
DR Proteomes; UP000002061; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0006400; P:tRNA modification; IEA:UniProt.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR NCBIfam; NF040721; Trm14_Arch; 1.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF143437; THUMP domain-like; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51165; THUMP; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:ADG13674.1};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000313|EMBL:ADG13674.1}.
FT DOMAIN 44..154
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 378 AA; 43332 MW; EC4AB5958CA24E69 CRC64;
MELYSTLSPG LEKIAKEEIE SLGGKVKEIR EERGRVFFEG DLKVMAKLNY FSRTLERINI
LLYRGEVESL EDIYEVIYNL DWTFIDENKS FAIRPLRVGS HNFTSIDIGR VAGEALIKSY
LRDKNVRLKV NLDEPDVIVR VELIHNELLV GLDTTGDIAL DKRGYRVYNH LAHLNSTIAA
SLIYLGNFRE YESLLDPMCG SATILIEGAL IRRNIPPGIF RERKYGFSFL NLFGRELLED
VKREVNINYE KYLIYGIDKN PKFLEGAKRN LESAMVDDTV NLILGDATKI DKIFNEVDLV
VVNPPYGIRL GKKRLLRELY NNFLLSVKRV MHGNSRVICI TAETKLFEEA IAKADLTVKE
KFNVKFGGLS TKVYYLTL
//
