ID D5WX29_KYRT2 Unreviewed; 1127 AA.
AC D5WX29;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE SubName: Full=Acriflavin resistance protein {ECO:0000313|EMBL:ADG07810.1};
GN OrderedLocusNames=Btus_3202 {ECO:0000313|EMBL:ADG07810.1};
OS Kyrpidia tusciae (strain DSM 2912 / NBRC 15312 / T2) (Bacillus tusciae).
OC Bacteria; Bacillota; Bacilli; Bacillales; Alicyclobacillaceae; Kyrpidia.
OX NCBI_TaxID=562970 {ECO:0000313|EMBL:ADG07810.1, ECO:0000313|Proteomes:UP000002368};
RN [1] {ECO:0000313|Proteomes:UP000002368}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2912 / NBRC 15312 / T2 {ECO:0000313|Proteomes:UP000002368};
RG US DOE Joint Genome Institute (JGI-PGF);
RA Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N.,
RA Ovchinnikova G., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F.,
RA Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T.,
RA Wu D., Pukall R., Schneider S., Wahrenburg C., Klenk H.-P., Eisen J.A.;
RT "The complete genome of Bacillus tusciae DSM 2912.";
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ADG07810.1, ECO:0000313|Proteomes:UP000002368}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 2912 / NBRC 15312 / T2 {ECO:0000313|Proteomes:UP000002368};
RX PubMed=22180816; DOI=10.4056/sigs.2144922;
RA Klenk H.P., Lapidus A., Chertkov O., Copeland A., Del Rio T.G., Nolan M.,
RA Lucas S., Chen F., Tice H., Cheng J.F., Han C., Bruce D., Goodwin L.,
RA Pitluck S., Pati A., Ivanova N., Mavromatis K., Daum C., Chen A.,
RA Palaniappan K., Chang Y.J., Land M., Hauser L., Jeffries C.D., Detter J.C.,
RA Rohde M., Abt B., Pukall R., Goker M., Bristow J., Markowitz V.,
RA Hugenholtz P., Eisen J.A.;
RT "Complete genome sequence of the thermophilic, hydrogen-oxidizing Bacillus
RT tusciae type strain (T2) and reclassification in the new genus, Kyrpidia
RT gen. nov. as Kyrpidia tusciae comb. nov. and emendation of the family
RT Alicyclobacillaceae da Costa and Rainey, 2010.";
RL Stand. Genomic Sci. 5:121-134(2011).
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DR EMBL; CP002017; ADG07810.1; -; Genomic_DNA.
DR RefSeq; WP_013077089.1; NC_014098.1.
DR AlphaFoldDB; D5WX29; -.
DR STRING; 562970.Btus_3202; -.
DR KEGG; bts:Btus_3202; -.
DR eggNOG; COG0841; Bacteria.
DR HOGENOM; CLU_002755_1_2_9; -.
DR Proteomes; UP000002368; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF16; CATION EFFLUX SYSTEM (ACRB_ACRD_ACRF FAMILY); 1.
DR Pfam; PF00873; ACR_tran; 2.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 354..373
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 380..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 456..476
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 488..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 598..616
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 958..977
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 984..1004
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1010..1031
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1059..1079
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1085..1108
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 531..574
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1127 AA; 122623 MW; AE7D5777ACB3740B CRC64;
MKIGLSGRIA KAFINSKITP LLVLAALLMG VLAVLNTPRE EEPQISVPMI DIFVPYPGAT
AKDVEDRVTK VLEKKLWKIK GVEYIYSTSQ PGQALITLRY YVGTDLNDAV VRTYNEVMSN
MDEVPPGVGQ PLVKPMTIDD VPIVSVTLWT NKLNDYDLRR ITAVVADEVN RVENVAKVQV
IGGRERQVRV EVDPTRLAAY GISPLTLERT LQSGNQSLDA GQFAEANKQF KVKAGTYLVD
PEQVKNLVVG VYDQRPVFLK DVATVTDGPS EVNRYVLFGT GPRAADKGVT EPPGRIFPAV
TISVSKKPGT NAVWVANDVI KKVDDLKGKV IPSDVQVTVT RDYGETAMEK ANELIDHLLI
ATASVILLIG VVLGIREAIV VGIAVPVTLA LALFLSYMHG YTLNRVTLFA LIFAIGILVD
DAIVVVENMH RWFRMRTLKP LDAAVRSVDE VGNPTILATF TVIAVLIPMA FVRGLMGPYM
APIPINASIA MFFSLLVAFV VTPWFGLRLL KRDEPEAAVA AAGVSGGREG TVAVGPTVTP
GDAPEAGTST GGASEDGPGA EGGRSGNGDH VGEEHGGRIS RMYAGVLMAM VHSRKKRNLF
FLAVVLMLIA SMGFFYTKAV AMKMLPFDNK SEFQVVIDMP RGTTLEQTAA ATKAIGDYLS
TVNEVTDYEM YIGTASPFNF NGLVRHYYLR QGPDVADIQV NLVAKGEREQ QSHDIAKRIR
PAVQAIGQKY GANVKVVEVP PGPPVQDTLV LEVYSNDPAD QYAAVQQAAE IFKKTPGVVD
VDTSLQAPQT QYSFTLTDQA RLNGITDQEV AQTLQVMLGG AQVGLVHPPH ELEPVKIWLQ
PPRDRRSSLD ELKSIQVPTP SGKLIPLGEV ANIQQETAEQ TLYRKNLQSV AYVFADVAGY
EESPAYDIAK MWNAVGQIHV PSGAKVEQYL THQPWLENGV KVKWDGEWQI TYEVFRDLGL
AFGVALVVMY LLVVAWFQSF ITPLVIMAPI PLTMIGVVPG HWLFGAFFTA TSMIGVIALA
GIIVRNSILL VEFAERRRKE GEDLDAAVVT AGVVRAKPIL LTAAAVVVGA FVILFDPIFQ
GLAISLMFGT IASTVLTLFV IPVLYYAVEI RRAKARMRRE AQAKANA
//
