ID D5WYS3_THIK1 Unreviewed; 431 AA.
AC D5WYS3;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 66.
DE SubName: Full=DNA-directed DNA polymerase {ECO:0000313|EMBL:ADG32250.1};
DE EC=2.7.7.7 {ECO:0000313|EMBL:ADG32250.1};
GN OrderedLocusNames=Tint_2912 {ECO:0000313|EMBL:ADG32250.1};
OS Thiomonas intermedia (strain K12) (Thiobacillus intermedius).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales; Thiomonas.
OX NCBI_TaxID=75379 {ECO:0000313|EMBL:ADG32250.1};
RN [1] {ECO:0000313|EMBL:ADG32250.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 {ECO:0000313|EMBL:ADG32250.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Kyrpides N., Ovchinnikova G., Kerfeld C.A., Cannon G.C.,
RA Heinhorst S., Woyke T.;
RT "Complete sequence of Thiomonas intermedia K12.";
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC {ECO:0000256|ARBA:ARBA00010945}.
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DR EMBL; CP002021; ADG32250.1; -; Genomic_DNA.
DR AlphaFoldDB; D5WYS3; -.
DR STRING; 75379.Tint_2912; -.
DR KEGG; tin:Tint_2912; -.
DR eggNOG; COG0389; Bacteria.
DR HOGENOM; CLU_012348_3_0_4; -.
DR BioCyc; TINT75379:TINT_RS14590-MONOMER; -.
DR GO; GO:0003684; F:damaged DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR GO; GO:0009432; P:SOS response; IEA:UniProtKB-KW.
DR CDD; cd01700; PolY_Pol_V_umuC; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR025188; DUF4113.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR11076; DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; 1.
DR PANTHER; PTHR11076:SF34; PROTEIN UMUC; 1.
DR Pfam; PF13438; DUF4113; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00023199};
KW DNA-directed DNA polymerase {ECO:0000313|EMBL:ADG32250.1};
KW Nucleotidyltransferase {ECO:0000313|EMBL:ADG32250.1};
KW SOS mutagenesis {ECO:0000256|ARBA:ARBA00023199};
KW SOS response {ECO:0000256|ARBA:ARBA00023236};
KW Transferase {ECO:0000313|EMBL:ADG32250.1}.
FT DOMAIN 2..196
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
SQ SEQUENCE 431 AA; 47659 MW; 70B060EDA9641AA3 CRC64;
MFALIDGNNF YASCECVFQP ELRGKPLVVL SNNDGCAIAR SDEAKALGVK MGQPIFEVPP
AVRRQLAIRS ANFTLYGDMS ARVLAILREA APRVESYSID ESFLDLTGIL KPGSREAFCR
ELRERVHRWT GIPNCVGIGA TKTLAKLGNH VAKSAVRKPG SYPAELGRVA DLSALSPQGL
SAVLAATPVG ELWGVGRRWA AKLRSMNIET ALQLRDAPRA LILDSFGVVL SRTQRELASE
PCLALEEVEP DRQQIMVSRS FGERVEDHQS IGEAFATFAM RACEKLRARG LVASAVGIFA
NTDHFRPELH QHHPQRTTDL PRATSDSRVV LNTIRQMQRG FLKDGYAYKK AGVWLMDLSR
PDQLQPDLFS TITIGDDKLM QTLDAINRRY GRGTVGLGAT GWRERPQWGM RQATLSSRFT
TSLRDLPRAI C
//
