ID D5X494_THIK1 Unreviewed; 672 AA.
AC D5X494;
DT 13-JUL-2010, integrated into UniProtKB/TrEMBL.
DT 13-JUL-2010, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE RecName: Full=NADH:quinone oxidoreductase/Mrp antiporter membrane subunit domain-containing protein {ECO:0000259|Pfam:PF00361};
GN OrderedLocusNames=Tint_0283 {ECO:0000313|EMBL:ADG29695.1};
OS Thiomonas intermedia (strain K12) (Thiobacillus intermedius).
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales; Thiomonas.
OX NCBI_TaxID=75379 {ECO:0000313|EMBL:ADG29695.1};
RN [1] {ECO:0000313|EMBL:ADG29695.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 {ECO:0000313|EMBL:ADG29695.1};
RG US DOE Joint Genome Institute;
RA Lucas S., Copeland A., Lapidus A., Cheng J.-F., Bruce D., Goodwin L.,
RA Pitluck S., Davenport K., Detter J.C., Han C., Tapia R., Land M.,
RA Hauser L., Kyrpides N., Ovchinnikova G., Kerfeld C.A., Cannon G.C.,
RA Heinhorst S., Woyke T.;
RT "Complete sequence of Thiomonas intermedia K12.";
RL Submitted (APR-2010) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU000320}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU000320}.
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DR EMBL; CP002021; ADG29695.1; -; Genomic_DNA.
DR AlphaFoldDB; D5X494; -.
DR STRING; 75379.Tint_0283; -.
DR KEGG; tin:Tint_0283; -.
DR eggNOG; COG0651; Bacteria.
DR HOGENOM; CLU_007100_8_1_4; -.
DR BioCyc; TINT75379:TINT_RS01420-MONOMER; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR InterPro; IPR003918; NADH_UbQ_OxRdtase.
DR InterPro; IPR001750; ND/Mrp_mem.
DR PANTHER; PTHR42682:SF3; HYDROGENASE-4 COMPONENT B; 1.
DR PANTHER; PTHR42682; HYDROGENASE-4 COMPONENT F; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR PRINTS; PR01437; NUOXDRDTASE4.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Transmembrane {ECO:0000256|RuleBase:RU000320, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 38..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 81..105
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 117..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 140..156
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 168..189
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 209..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 246..263
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 275..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..345
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 388..413
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 433..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 480..501
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 536..557
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 652..671
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 134..416
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
SQ SEQUENCE 672 AA; 72576 MW; C0891DEE9DC6F516 CRC64;
MNASDLLPIA LGVVAAWVCM GLAGFISPRS TRWVARVIFP LGALGSLVMA AVGLLALFAA
PQSMVLPIGL PGLPLHFRLD ALSGFFLFLL GASTVGISTF ASGYFREGEG TAPGLLGMQY
HVFLAAMCMV MLAADAYSFM LSWEVMAMAS YFLVISQHRM AEIRSAGYVY LLLAHLGAIA
LLLCFGVMMQ GGIASLTFEA MRHAHLSPAW ASVAFGLAVI GFGAKAGLVP LHIWLPEAHP
AAPSPVSALM SGVMLKTALY GLLRVSFDLL HAPLWWWGVP LLALGLFGAL FGVLFAAVQT
DMKRLLAYSS IENIGIAFAA LGLALVFHGV GLAVFAALAL AAMLYHLLNH AFFKSLLFLT
TGSVLHATHQ RSLGKLGGLL RTMPWVGWTA LIGTLAIAGL PPLNGFVAEW LLLQSFLFTP
QIPEPFFNLL IPLGAAMLVL TAALAAYVMV KFYGVIFLGR AREPQLEQAH DVGWLERIGL
LWLAAGCVLL GLIPTWVLQA IDRVNLMLLG KPLAQAGDAS MGNWFWLVPL SPDRASYSPV
AILLVGLLVV GLTGLLTHRV YAGRVRRAAP WDCGAPGLTG RMQDSAEGFG QPIRRVFSPF
FLMRVELPRP DDAAPRYRVS VEDRFWPQFY TPAAQAVLWL ARQVGKIQQG RISVYLLYSF
LTLLVLLMVV LR
//
